Journal profile · Medicine-General Medicine
JCI Insight
ISSN 2379-3708 · The American Society for Clinical Investigation · United States
JCI Insight: CAS Zone 1 · Medicine (2025 upgraded edition, Top journal); impact factor 6.72; fully open access; APC about USD 5,000; median 242 days to acceptance (65 articles, last 24 months); 545 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
JCI Insight is published by The American Society for Clinical Investigation and is in Zone 1 of Medicine in the CAS Journal Ranking (2025 upgraded edition, Top journal). By OpenAlex counts of its recent articles, its largest topics are Immune Cell Function and Interaction, T-cell and B-cell Immunology and Immunotherapy and Immune Responses, together about 27.7% of its articles. Its main subfields are Immunology. (generated from OpenAlex topic counts and CAS ranking data)
JCI Insight is a peer-reviewed journal dedicated to biomedical research, ranging from preclinical to clinical studies. JCI Insight is a Gold Open Access journal that has a 2025 Impact Factor of 6.8. See journal metrics here. The Journal publishes well-executed, high-quality studies that provide meaningful contributions to the understanding of the biology and/or treatment of disease, with an emphasis on clinically relevant basic and translational research. Submissions are welcome from all biomedical specialties, including autoimmunity, gastroenterology, immunology, metabolism, nephrology, neuroscience, oncology, pulmonology, vascular biology, and many others. JCI Insight is self-published by the American Society for Clinical Investigation (ASCI), a nonprofit honor organization of physician-scientists established in 1908. JCI Insight serves to fulfill the ASCI’s objective to advance medical science through the publication of clinically relevant research reports.
From the journal's Aims & Scope
Research area (LetPub): Medicine-General Medicine
Editor-in-chief Oliver EickelbergPublisher website
Main research topics OpenAlex counts of recent articles; shares are approximate
- Immune Cell Function and InteractionImmunology and Microbiology13.2%
- T-cell and B-cell ImmunologyImmunology and Microbiology8.7%
- Immunotherapy and Immune ResponsesImmunology and Microbiology5.8%
- Immune cells in cancerImmunology and Microbiology5.7%
- Pancreatic function and diabetesMedicine4.6%
- Cancer Immunotherapy and BiomarkersMedicine4.6%
- CAR-T cell therapy researchMedicine3.9%
- SARS-CoV-2 and COVID-19 ResearchMedicine3.8%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 1 |
| Minor | Medicine, Research & Experimental | Zone 1 |
Top journal: yesReview journal: no
CAS Xinrui Journal Ranking (March 2026)Medicine Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 1 |
| Minor | Medicine, Research & Experimental | Zone 2 |
Top journal: yesReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 1 |
| Minor | Medicine, Research & Experimental | Zone 1 |
Top journal: yesReview journal: no
Database indexing
SCIEScopusDOAJLetPub
International journal early-warning lists: not listed in any editionLetPub
Indexing the journal's website claims
Web of ScienceMEDLINEPMCEmbaseCASPublisher website
Other: Google Scholar, ProQuest, Crossref, Sherpa Romeo, ProQuest Biological Science Collection
As the journal's website lists them, not checked against each database; for Web of Science editions the records above apply.
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 6.72LetPub ·
- Impact factor (publisher) 2025
- 6.8Publisher website ·
- CiteScore 2026-06
- 10.8LetPub ·
- SJR 2026-06
- 2.83LetPub ·
- SNIP 2026-06
- 1.49LetPub ·
- h-index
- 175OpenAlex ·
- i10-index
- 4,016OpenAlex ·
- 2-year mean citedness
- 6.39OpenAlex ·
- Self-citation rate
- 0%LetPub ·
- Share of gold OA articles
- 99.54%LetPub ·
Volume
- Articles per year
- 520LetPub ·
Articles by year OpenAlex count · 5,448 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 489 | 489 | 293 |
| 2025 | 545 | 545 | 2,811 |
| 2024 | 532 | 532 | 6,902 |
| 2023 | 500 | 500 | 11,448 |
| 2022 | 557 | 557 | 17,858 |
| 2021 | 575 | 575 | 23,398 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with PubMed · to
242 daysMedian, submission to acceptance · P25–P75 177 days – 333 days
- Acceptance to online
- median 14 days (65 articles)
- Submission to online
- median 280 days
- Sample
- 65 articles with submission and acceptance dates (1,191 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Average review time (community reports)
- about 6 weeksLetPub ·
- Submission to publication (journal-reported)
- about 6 weeksDOAJ ·
- Peer review
- Single anonymous peer reviewDOAJ
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Fully open accessDOAJ
Every article is open access; authors usually pay an article processing charge (APC).
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| DOAJ | USD 5,000 | Yes | CC BY | |
| OpenAlex | USD 4,100 | — | — | |
| Publisher website | USD 5,000 / USD 4,800 / USD 4,500 / USD 2,500 / USD 2,400 / USD 2,250 | — | — |
Other charges and waivers (author guidelines)
- Submission fee
- USD 2,250
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
Article types accepted7
- clinical research and public healthClinical Research and Public Health manuscripts report findings derived from human participants, ranging from studies with a small number of patients to large-c…Length not stated
- editorial[Top of page] Submissions Dual-Journal Submission Prior publication Review of manuscripts Tranfers of reviews from other journals Guaranteed reviews and rewards…Length not stated
- physician-scientist developmentPhysician-Scientist Development manuscripts focus on studies aimed to improve physician-scientist education, training, retention, and career development.Length not stated
- researchResearch manuscripts report new insights into biology and disease using preclinical models as well as materials and data derived from humans.Length not stated
- research letterResearch Letter manuscripts are focused reports of an original preclinical or clinical research finding of exceptional interest to the JCI Insight readership.Length not stated
- resource and technical advanceResource and Technical Advance manuscripts introduce major databases and/or describe new research tools.Length not stated
- review[Top of page] | [Editorial policies and practices] The Science Editors assign manuscripts to appropriate Associate Editors. Papers may be rejected without exter…Length not stated
Policy excerpts from the journal's websiteAuthorship, Conflicts of interest, Data availability, Publication ethics, License & copyright, Open access, Preprints, Self-archiving
- Authorship Authorship agreement
[Top of page] | [Editorial policies and practices] For revised manuscript submissions, all authors listed on the submission site must approve the submission before the revised version can be sent to the Editorial Board for review. Each listed author will receive an electronic notification, at the email addresses provided at the time of submission, requesting approval. Any changes in authorship ord…
Source ↗Publisher website ·- Conflicts of interest Conflicts of interest
[Top of page] | [Editorial policies and practices] Editors Authors Reviewers Misconduct allegations JCI Insight and the American Society for Clinical Investigation (ASCI) are dedicated to upholding the highest standards of integrity and ethical conduct in research, and in its evaluation and related communication. It is important that the Editors, authors, and referees conduct themselves in accorda…
Source ↗Publisher website ·- Data availability Data availability
[Top of page] | [Editorial policies and practices] The Methods section must include a paragraph titled “Data availability” detailing how underlying data and supporting analytic code can be accessed by providing, as applicable: a callout to the Supporting Data Values file, which includes values underlying graphed data and reported means presented in both the main text and supplemental material for …
Source ↗Publisher website ·- Publication ethics Misconduct allegations
[Top of page] | [Conflicts of interest] Allegations of scientific misconduct in the JCI family of publications are taken very seriously and carefully reviewed by the Editors. The Journal holds high standards regarding transparency in conflicts of interest for individuals alleging misconduct just as we do for our Editors, Authors, and Reviewers. Individuals alleging misconduct may still opt to rema…
Source ↗Publisher website ·- License & copyright Copyright
[Top of page] Authors retain copyright on all articles, which are published with a Creative Commons Attribution License (CC BY 4.0). See Open access for detailed information.
Source ↗Publisher website ·- Open access
cOAlition S compliant; fully compliant with HHMI, Wellcome, and UKRI open access policies Model summary
JCI Insight meets cOAlition S requirements for authors who receive funding support from Plan S signatories and is fully compliant with Howard Hughes Medical Institute (HHMI), Wellcome, and UK Research and Innovation (UKRI) open access policies.
Source ↗Publisher website ·- Preprints
Dual-Journal Submission option with JCI Model summary
Dual-Journal Submission gives you the option to submit your work for consideration by both the JCI and JCI Insight.
Source ↗Publisher website ·- Self-archiving
Deposits all content in PubMed Central, satisfying NIH Public Access Policy Model summary
The Journal deposits all content in PubMed Central, which satisfies the NIH Public Access Policy and other similar funding agency requirements.
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- The American Society for Clinical Investigation
- Country or region
- United States
- Language
- English
- ISSN
- 2379-3708
- Official links
FAQ
Frequently asked questions about JCI Insight
What CAS zone is JCI Insight in?
In the 2025 upgraded edition of the CAS Journal Ranking, JCI Insight is in Zone 1 of Medicine, and in Zone 1 of the minor category Medicine, Research & Experimental; it is a Top journal. In the 2026 Xinrui edition it is in Zone 1 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of JCI Insight?
The latest impact factor listed by LetPub is 6.72; CiteScore 10.8, h-index 175.
How long does peer review take at JCI Insight?
Based on the dates recorded on 65 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 242 days (interquartile range 177–333 days); authors report an average review time of about 6 weeks. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
Which databases index JCI Insight?
According to LetPub and DOAJ records, JCI Insight is indexed in SCIE, Scopus and DOAJ. The journal's website also lists Web of Science, MEDLINE, PMC, Embase and CAS; that list has not been checked against each database.
Is JCI Insight open access, and what is the APC?
JCI Insight is a fully open-access journal. APC about USD 5,000.
Sources and updates
The facts on this page come from LetPub, OpenAlex, DOAJ, Publisher website; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .