Journal profile · Biochemistry & Molecular Biology

Nature Medicine

ISSN 1078-8956 · eISSN 1546-170X · Springer Nature · UNITED STATES · Monthly · Founded 1995

Nature Medicine: CAS Zone 1 · Medicine (2025 upgraded edition, Top journal); impact factor 52.24; hybrid open access; APC about USD 12,690; median 165 days to acceptance (69 articles, last 24 months); community-reported acceptance: about 15%; 748 articles in 2025; indexed in SCIE and Scopus.

Impact factor52.24Latest value listed by LetPub
CAS zoneZone 1 · Medicine2025 upgraded edition, major category · Top journal · 2026 Xinrui edition Zone 1 · Medicine
Review time165 daysMedian, submission to acceptance · 69 articles, last 24 months · Crossref
APCUSD 12,690Hybrid journal: charged only for open-access articles
Acceptanceabout 15%Community average
Articles per year7482025 · OpenAlex count

Scope

Aims, scope and focus

Nature Medicine is published by Springer Nature and is in Zone 1 of Medicine in the CAS Journal Ranking (2025 upgraded edition, Top journal). By OpenAlex counts of its recent articles, its largest topics are Science, Research, and Medicine, Immune Cell Function and Interaction and Immunotherapy and Immune Responses, together about 23.5% of its articles. Its main subfields are Immunology. (generated from OpenAlex topic counts and CAS ranking data)

Nature Medicine is a monthly journal publishing original peer-reviewed research in all areas of medicine on the basis of its originality, timeliness, interdisciplinary interest and impact on improving human health. Nature Medicine also publishes commissioned content, including News, Reviews and Perspectives, aimed at contextualizing the latest advances in translational and clinical research to reach a wide audience of M.D. and Ph.D. readers. All editorial decisions are made by a team of full-time professional editors.

From the journal's Aims & Scope

Research area (LetPub): Biochemistry & Molecular Biology

Editorial board by country: 1 in mainland China (about 8%); most named United States 5, United Kingdom 2, Germany 2, Mainland China 1, Italy 1 (12 members with a country) Editorial board ↗Publisher website ·

Main research topics OpenAlex counts of recent articles; shares are approximate

  1. Science, Research, and MedicineMedicine9.7%
  2. Immune Cell Function and InteractionImmunology and Microbiology7.5%
  3. Immunotherapy and Immune ResponsesImmunology and Microbiology6.3%
  4. Biotechnology and Related FieldsMedicine5.5%
  5. HIV Research and TreatmentImmunology and Microbiology5.4%
  6. Biomedical Ethics and RegulationMedicine5.4%
  7. T-cell and B-cell ImmunologyImmunology and Microbiology5%
  8. Health and Medical Research ImpactsMedicine4.8%

Rankings & indexing

CAS ranking and database indexing

CAS Journal Ranking

CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 1
LevelCategoryZone
MajorMedicineZone 1
MinorBiochemistry & Molecular BiologyZone 1
MinorCell BiologyZone 1
MinorMedicine, Research & ExperimentalZone 1

Top journal: yesReview journal: no

CAS Xinrui Journal Ranking (March 2026)Medicine Zone 1
LevelCategoryZone
MajorMedicineZone 1
MinorBiochemistry & Molecular BiologyZone 1
MinorCell BiologyZone 1
MinorMedicine, Research & ExperimentalZone 1

Top journal: yesReview journal: not marked

CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 1
LevelCategoryZone
MajorMedicineZone 1
MinorBiochemistry & Molecular BiologyZone 1
MinorCell BiologyZone 1
MinorMedicine, Research & ExperimentalZone 1

Top journal: yesReview journal: no

Database indexing

SCIEScopusLetPub

International journal early-warning lists: not listed in any editionLetPub

Indexing the journal's website claims

Web of SciencePublisher website

As the journal's website lists them, not checked against each database; for Web of Science editions the records above apply.

Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.

Metrics

Impact metrics and publication volume

Impact

Impact factor
52.24LetPub ·
Impact factor (publisher) 2025
52.5Publisher website ·
5-year impact factor (publisher) 2025
52.5Publisher website ·
CiteScore 2026-06
73.9LetPub ·
SJR 2026-06
17.5LetPub ·
SNIP 2026-06
9.84LetPub ·
h-index
497LetPub ·
h-index
773OpenAlex ·
i10-index
8,798OpenAlex ·
2-year mean citedness
32.32OpenAlex ·
Self-citation rate
1.1%LetPub ·
Share of gold OA articles
61.4%LetPub ·

Volume

Articles per year
364LetPub ·
Downloads per year (publisher) 2025
25,697,615Publisher website ·

Articles by year OpenAlex count · 16,790 in total · the current year is incomplete

YearArticlesOpen accessCitations
20266293092,755
202574840923,636
202471439241,189
202364335051,559
202257232572,057
202150829389,389

Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.

Review & acceptance

Review time and acceptance

Review time from article dates manuscript dates registered with Crossref · to

165 daysMedian, submission to acceptance · P25–P75 127 days – 239 days

Acceptance to online
median 39 days (69 articles)
Submission to online
median 217 days
Sample
69 articles with submission and acceptance dates (1,473 in the window); the latest was accepted on

Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".

Other sources

Average review time (community reports)
about 1 monthLetPub ·
Average acceptance (community reports)
15%LetPub ·
Peer review
Double anonymous peer reviewPublisher website

Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.

Fees & open access

APC and open-access policy

Hybrid open accessLetPub

A subscription journal in which authors can pay to publish their article open access.

SourceAPCFee waiverLicenseObserved
OpenAlexUSD 12,690 / EUR 10,690 / GBP 9,190——

A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.

The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.

Submission

Article types and submission policies (journal website)

Policy excerpts from the journal's websitePeer review, Preprints
Peer review 3 – Editorial Process, Peer Review, Appeals & Transfers

Once you have submitted your manuscript, it goes through our editorial process. If your manuscript is sent out for peer review, you will receive an email asking you to read and sign our Editorial Policies. To appeal against a decision, or transfer your submission to another journal – Appeals and Transfers. ____________________________________________________________________________________________…

Source ↗Publisher website ·
Preprints

Editorial policies Model summary

Read and understand our policies – Editorial policies

Source ↗Publisher website ·

Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.

Profile

Publication details and official links

Publisher
Springer Nature
Country or region
UNITED STATES
Language
English
Frequency
Monthly
Founded
1995
ISSN
1078-8956
Electronic ISSN
1546-170X
Official links

FAQ

Frequently asked questions about Nature Medicine

What CAS zone is Nature Medicine in?

In the 2025 upgraded edition of the CAS Journal Ranking, Nature Medicine is in Zone 1 of Medicine, and in Zone 1 of the minor category Biochemistry & Molecular Biology / Cell Biology / Medicine, Research & Experimental; it is a Top journal. In the 2026 Xinrui edition it is in Zone 1 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.

What is the impact factor of Nature Medicine?

The latest impact factor listed by LetPub is 52.24; CiteScore 73.9, h-index 773.

How long does peer review take at Nature Medicine?

Based on the dates recorded on 69 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 165 days (interquartile range 127–239 days); authors report an average review time of about 1 month; the community-reported acceptance is “about 15%”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.

Where are the editorial board members of Nature Medicine based?

Of the 12 board members whose country the journal's board page names, 1 (about 8%) are in mainland China; the countries named most often are United States (5), United Kingdom (2) and Germany (2). Counted from the institutions listed on the board page; for reference only.

Which databases index Nature Medicine?

According to LetPub and DOAJ records, Nature Medicine is indexed in SCIE and Scopus. The journal's website also lists Web of Science; that list has not been checked against each database.

Is Nature Medicine open access, and what is the APC?

Nature Medicine is a hybrid journal. For open-access publication: APC about USD 12,690.

Sources and updates

The facts on this page come from LetPub, OpenAlex, Publisher website; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-26). Last updated: .