Journal profile · Toxicology
Human & Experimental Toxicology
ISSN 0960-3271 · eISSN 1477-0903 · SAGE Publications Inc. · ENGLAND · Monthly · Founded 1990
Human & Experimental Toxicology: CAS Zone 4 · Medicine (2025 upgraded edition); impact factor 3.56; fully open access; APC about USD 2,800; review about 2.3 months (community reports); community-reported acceptance: about 51.66%; 71 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
Human & Experimental Toxicology is published by SAGE Publications Inc. and is in Zone 4 of Medicine in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Pesticide Exposure and Toxicity, Carcinogens and Genotoxicity Assessment and Poisoning and overdose treatments, together about 30.9% of its articles. Its main subfields are Health, Toxicology and Mutagenesis. (generated from OpenAlex topic counts and CAS ranking data)
Human and Experimental Toxicology (HET), an international, peer-reviewed, open access journal, is dedicated to publishing nonclinical and clinical original research papers and in-depth reviews that comprehensively cover functional, biochemical, and structural disorders in toxicology. The principal aim of HET is to publish timely high impact hypothesis driven scholarly work with an international scope.The journal publishes on:Structural, functional, biochemical, and molecular effects of toxic agentsStudies that address mechanisms/modes of toxicitySafety evaluation of novel chemical, biotechnologically-derived products, and nanomaterials for human health assessment including statistical and mechanism-based approachesNovel methods or approaches to research on animal and human tissues (medical and veterinary patients) investigating the functional, biochemical, and structural disorderIn vitro techniques, particularly those supporting alternative methodsNovel approaches exploring e.g. adverse outcome pathways, also in the context of risk assessment of chemicalsPapers will be judged based on scientific originality and contribution to the field and quality and subject matter. Papers describing effects on humans or experimental animals only of local interests; it is important that the results can be generalized to wider audiences and applications. Authors must clearly identify chemically the material tested and briefly explain what novel toxic effect (s) or toxic mechanism (s) of the chemical is being reported and what their significance is.HET does not accept case reports and case studies. HET does not accept papers on herbal or other extracts unless sufficient chemical characterization of the material under investigation is supplied. HET does not publish routine toxicological studies without an aim to define novel mechanisms of toxicity. The same applies to studies that utilize excessive doses of chemicals/toxicants without any relevance with the human situation. Open access informationFrom January 2022, HET will become a fully open access journal. All articles that are accepted for publication will be subject to an open access article processing charge (APC) of $3200 and will be published with a Creative Commons license.The APC is payable when a manuscript is accepted after peer review, before it is published. The APC is subject to taxes where applicable. Please see further details here.Submit your manuscript today at https://mc.manuscriptcentral.com/het.
From the journal's Aims & Scope
Research area (LetPub): Toxicology
Editor-in-chief Catherine MaryPublisher website
Editorial board by country: 2 in mainland China (about 5%); most named United States 15, India 5, Türkiye 3, Malaysia 3, Mainland China 2 (43 members with a country) Editorial board ↗Publisher website ·
Main research topics OpenAlex counts of recent articles; shares are approximate
- Pesticide Exposure and ToxicityAgricultural and Biological Sciences10.8%
- Carcinogens and Genotoxicity AssessmentBiochemistry, Genetics and Molecular Biology10.4%
- Poisoning and overdose treatmentsMedicine9.7%
- Heavy Metal Exposure and ToxicityEnvironmental Science7.4%
- Drug-Induced Hepatotoxicity and ProtectionPharmacology, Toxicology and Pharmaceutics6.8%
- Effects and risks of endocrine disrupting chemicalsEnvironmental Science5.5%
- Animal testing and alternativesVeterinary4.1%
- Toxic Organic Pollutants ImpactEnvironmental Science3.5%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 4 |
| Minor | Toxicology | Zone 4 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Medicine Zone 3
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 3 |
| Minor | Toxicology | Zone 3 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 4 |
| Minor | Toxicology | Zone 4 |
Top journal: noReview journal: no
Database indexing
SCIEScopusDOAJLetPub
International journal early-warning lists: not listed in any editionLetPub
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 3.56LetPub ·
- Impact factor (publisher)
- 3.5Publisher website ·
- 5-year impact factor (publisher)
- 3.2Publisher website ·
- CiteScore 2026-06
- 7.1LetPub ·
- SJR 2026-06
- 0.81LetPub ·
- SNIP 2026-06
- 0.87LetPub ·
- h-index
- 71LetPub ·
- h-index
- 113OpenAlex ·
- i10-index
- 2,892OpenAlex ·
- 2-year mean citedness
- 3.58OpenAlex ·
- Self-citation rate
- 2.9%LetPub ·
- Share of gold OA articles
- 100%LetPub ·
Volume
- Articles per year
- 58LetPub ·
Articles by year OpenAlex count · 4,782 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 25 | 25 | 9 |
| 2025 | 71 | 71 | 150 |
| 2024 | 67 | 67 | 425 |
| 2023 | 113 | 113 | 1,134 |
| 2022 | 153 | 153 | 1,961 |
| 2021 | 175 | 53 | 2,687 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
- Average review time (community reports)
- about 2.3 monthsLetPub ·
- Average acceptance (community reports)
- 51.66%LetPub ·
- Acceptance rate (publisher)
- 10.2%Publisher website ·
- Submission to first decision
- 3 daysPublisher website ·
- Acceptance to publication
- 30 daysPublisher website ·
- Submission to publication (journal-reported)
- about 13 weeksDOAJ ·
- Peer review
- Double anonymous peer reviewDOAJ
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Fully open accessDOAJ
Every article is open access; authors usually pay an article processing charge (APC).
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| DOAJ | USD 2,800 | Yes | CC BY, CC BY-NC | |
| OpenAlex | USD 2,800 | — | — | |
| Publisher website | USD 3,200 | — | — |
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
What to prepare8 items from the author guidelines
- Abstract
- ≤ 200 words
- Reference style
- Vancouver
- First submission
- Free format: the journal's layout is not required
- Suggested reviewers
- Optional
- Highlights
- Required
- Graphical abstract
- Optional
- Cover letter
- Required
- Not considered
- case studies/reports
Article types accepted6
- case studyView our Special Collections currently accepting submissions: https://journals.sagepub.com/page/het/call-for-papers/index. Please visit the Sage Journal Author …Length not stated
- mini-reviewsThe journal will publish both mini-reviews (abouLength not stated
- original researchView our Special Collections currently accepting submissions: https://journals.sagepub.com/page/het/call-for-papers/index. Please visit the Sage Journal Author …Length not stated
- reviewView our Special Collections currently accepting submissions: https://journals.sagepub.com/page/het/call-for-papers/index. Please visit the Sage Journal Author …Length not stated
- review articleView our Special Collections currently accepting submissions: https://journals.sagepub.com/page/het/call-for-papers/index. Please visit the Sage Journal Author …Length not stated
- review articlesReview articles The editors invite review articles on relevant and current topics in toxicology.Length not stated
Policy excerpts from the journal's websiteAuthorship, Data availability, Publication ethics, Open access, Peer review, Plagiarism, Preprints, Trial registration / reporting guidelines
- Authorship Author contributions
You will be asked to list the contribution of each author as part of the submission process. Please include the Author Contributions heading within your submission after the Acknowledgements section. The information you give on submission will then show under the Author Contributions heading later at the proofing stage.
Source ↗Publisher website ·- Data availability Data availability
The Journal is committed to facilitating openness, transparency and reproducibility of research, and has the following research data sharing policy. For more information, including FAQs please visit the Sage Research Data policy pages. As a condition of publication authors are required to: Share your research data in a relevant public data repository Include a data availability statement. This sho…
Source ↗Publisher website ·- Publication ethics Ethical considerations
Member of Committee on Publication Ethics Model summary
Please include your ethics approval statements under this heading, even if you have already included ethics approval information in your methods section. If ethical approval was not required, you need to explicitly state this. All papers reporting studies involving human participants, human data or human tissue must state that the relevant Ethics Committee or Institutional Review Board approved th…
Source ↗Publisher website ·- Open access Publishing fees and open access
Human & Experimental Toxicology is an open access, peer-reviewed journal. All accepted articles are made freely available online immediately upon publication, are published under a Creative Commons license, and hosted online in perpetuity. If, after peer review, your manuscript is accepted for publication, a one-time article processing charge (APC) is payable to cover the cost of publishing, paid …
Source ↗Publisher website ·- Peer review Peer review policy
Single anonymized peer review Model summary
The following summary describes the peer review process for this journal: Identity transparency: Single-anonymized Reviewer interacts with: Editor Review information published: None Your manuscript will undergo an initial evaluation. If it does not conform to the requirements laid out in these guidelines, it will be returned to you for amendments prior to peer review. Manuscripts may be desk rejec…
Source ↗Publisher website ·- Plagiarism Plagiarism
The journal and Sage take issues of copyright infringement, plagiarism or other breaches of best practice in publication very seriously. Please read Sage's complete policy on plagiarism and the actions we may take.
Source ↗Publisher website ·- Preprints Preprints
The journal will consider submissions of manuscripts that have been posted on preprint servers. Please enter the preprint DOI in the designated field when submitting your manuscript. We advise that you inform the Journal Editorial office about your posted preprint at submission. Note that you should not post an updated version of your manuscript on a preprint server while it is being peer reviewed…
Source ↗Publisher website ·- Trial registration / reporting guidelines Clinical trial registration
The journal conforms to the ICMJE requirement that clinical trials are registered in a WHO-approved public trials registry at or before the time of first participant enrollment as a condition of consideration for publication. The trial registry name and URL, and registration number must be included at the end of the abstract.
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- SAGE Publications Inc.
- Country or region
- ENGLAND
- Language
- English
- Frequency
- Monthly
- Founded
- 1990
- ISSN
- 0960-3271
- Electronic ISSN
- 1477-0903
- Official links
- Journal homepage ↗DOAJ
- Submission system ↗Publisher website
- Author guidelines ↗DOAJ
- Aims & Scope ↗DOAJ
- Special issues ↗Publisher website
- APC information ↗DOAJ
- Fee waivers ↗DOAJ
- Open access statement ↗DOAJ
- License & copyright ↗DOAJ
- Peer review process ↗DOAJ
- Editorial board ↗DOAJ
- Plagiarism policy ↗DOAJ
FAQ
Frequently asked questions about Human & Experimental Toxicology
What CAS zone is Human & Experimental Toxicology in?
In the 2025 upgraded edition of the CAS Journal Ranking, Human & Experimental Toxicology is in Zone 4 of Medicine, and in Zone 4 of the minor category Toxicology. In the 2026 Xinrui edition it is in Zone 3 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Human & Experimental Toxicology?
The latest impact factor listed by LetPub is 3.56; CiteScore 7.1, h-index 113.
How long does peer review take at Human & Experimental Toxicology?
Authors report an average review time of about 2.3 months; the community-reported acceptance is “about 51.66%”; the journal's website gives an acceptance rate of 10.2%. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
What are the manuscript requirements of Human & Experimental Toxicology?
According to the journal's author guidelines: Abstract: ≤ 200 words; Reference style: Vancouver; First submission: Free format: the journal's layout is not required; Suggested reviewers: Optional; Highlights: Required; Graphical abstract: Optional; Cover letter: Required. A model extracted these from the author guidelines and each was checked against the text; check the latest version on the journal's website before submitting.
Where are the editorial board members of Human & Experimental Toxicology based?
Of the 43 board members whose country the journal's board page names, 2 (about 5%) are in mainland China; the countries named most often are United States (15), India (5) and Türkiye (3). Counted from the institutions listed on the board page; for reference only.
Which databases index Human & Experimental Toxicology?
According to LetPub and DOAJ records, Human & Experimental Toxicology is indexed in SCIE, Scopus and DOAJ.
Is Human & Experimental Toxicology open access, and what is the APC?
Human & Experimental Toxicology is a fully open-access journal. APC about USD 2,800.
Sources and updates
The facts on this page come from LetPub, Publisher website, OpenAlex, DOAJ; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-28). Last updated: .