Journal profile · Toxicology
Annual Review of Pharmacology and Toxicology
ISSN 0362-1642 · eISSN 1545-4304 · Annual Reviews Inc. · UNITED STATES · Annual · Founded 1976
Annual Review of Pharmacology and Toxicology: CAS Zone 1 · Medicine (2025 upgraded edition, Top journal); impact factor 18.78; subscription journal; community-reported acceptance: mostly invited papers; 33 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
Annual Review of Pharmacology and Toxicology is published by Annual Reviews Inc. and is in Zone 1 of Medicine in the CAS Journal Ranking (2025 upgraded edition, Top journal). By OpenAlex counts of its recent articles, its largest topics are Receptor Mechanisms and Signaling, Computational Drug Discovery Methods and Pharmacogenetics and Drug Metabolism, together about 35.2% of its articles. Its main subfields are Molecular Biology. (generated from OpenAlex topic counts and CAS ranking data)
AIMS AND SCOPE OF JOURNAL: The Annual Review of Pharmacology and Toxicology covers the significant developments in the fields of pharmacology and toxicology, including receptors, transporters, enzymes, and chemical agents; drug development science; systems such as the immune system, central and autonomic nervous systems, gastrointestinal system, cardiovascular system, endocrine system, and pulmonary system; and special topics.  
From the journal's Aims & Scope
Research area (LetPub): Toxicology
Main research topics OpenAlex counts of recent articles; shares are approximate
- Receptor Mechanisms and SignalingBiochemistry, Genetics and Molecular Biology13.6%
- Computational Drug Discovery MethodsComputer Science11.9%
- Pharmacogenetics and Drug MetabolismPharmacology, Toxicology and Pharmaceutics9.7%
- Neuroscience and Neuropharmacology ResearchNeuroscience7.3%
- Neuropeptides and Animal PhysiologyNeuroscience5.8%
- Eicosanoids and Hypertension PharmacologyBiochemistry, Genetics and Molecular Biology4.9%
- Heme Oxygenase-1 and Carbon MonoxideBiochemistry, Genetics and Molecular Biology4.8%
- Drug Transport and Resistance MechanismsMedicine3.9%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 1 |
| Minor | Pharmacology & Pharmacy | Zone 1 |
| Minor | Toxicology | Zone 1 |
Top journal: yesReview journal: yes
CAS Xinrui Journal Ranking (March 2026)Medicine Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 1 |
| Minor | Pharmacology & Pharmacy | Zone 1 |
| Minor | Toxicology | Zone 1 |
Top journal: yesReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 1 |
| Minor | Pharmacology & Pharmacy | Zone 1 |
| Minor | Toxicology | Zone 1 |
Top journal: noReview journal: yes
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 18.78LetPub ·
- Impact factor (publisher)
- 19Publisher website ·
- CiteScore 2026-06
- 29.5LetPub ·
- SJR 2026-06
- 4.93LetPub ·
- SNIP 2026-06
- 3.95LetPub ·
- h-index
- 193LetPub ·
- h-index
- 298OpenAlex ·
- i10-index
- 1,317OpenAlex ·
- 2-year mean citedness
- 10.61OpenAlex ·
- Self-citation rate
- 0.5%LetPub ·
- Share of gold OA articles
- 100%LetPub ·
Volume
- Articles per year
- 29LetPub ·
Articles by year OpenAlex count · 1,713 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 18 | 4 | 15 |
| 2025 | 33 | 32 | 181 |
| 2024 | 24 | 24 | 600 |
| 2023 | 36 | 35 | 1,884 |
| 2022 | 30 | 29 | 1,727 |
| 2021 | 35 | 19 | 2,159 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
- Average acceptance (community reports)
- Mostly invited papersLetPub ·
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Subscription journalLetPub
A subscription journal: articles are read by subscription or purchase, and authors usually pay no publication charge.
No source has fee information yet; check the journal's website.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Profile
Publication details and official links
- Publisher
- Annual Reviews Inc.
- Country or region
- UNITED STATES
- Language
- English
- Frequency
- Annual
- Founded
- 1976
- ISSN
- 0362-1642
- Electronic ISSN
- 1545-4304
- Official links
- Journal homepage ↗LetPub
- Special issues ↗Publisher website
FAQ
Frequently asked questions about Annual Review of Pharmacology and Toxicology
What CAS zone is Annual Review of Pharmacology and Toxicology in?
In the 2025 upgraded edition of the CAS Journal Ranking, Annual Review of Pharmacology and Toxicology is in Zone 1 of Medicine, and in Zone 1 of the minor category Pharmacology & Pharmacy / Toxicology; it is a Top journal. In the 2026 Xinrui edition it is in Zone 1 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Annual Review of Pharmacology and Toxicology?
The latest impact factor listed by LetPub is 18.78; CiteScore 29.5, h-index 298.
Which databases index Annual Review of Pharmacology and Toxicology?
According to LetPub and DOAJ records, Annual Review of Pharmacology and Toxicology is indexed in SCIE and Scopus.
Is Annual Review of Pharmacology and Toxicology open access, and what is the APC?
Annual Review of Pharmacology and Toxicology is a subscription journal. Fee information is not available yet; check the journal's website.
Sources and updates
The facts on this page come from LetPub, OpenAlex, Publisher website; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .