Journal profile · MEDICINE, RESEARCH & EXPERIMENTAL
WIREs Mechanisms of Disease
ISSN 2692-9368 · Wiley-Blackwell
WIREs Mechanisms of Disease: CAS Zone 2 · Medicine (2025 upgraded edition); impact factor 5.42; hybrid open access; APC about USD 4,650; median 156 days to acceptance (11 articles, last 24 months); 16 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
WIREs Mechanisms of Disease is published by Wiley-Blackwell and is in Zone 2 of Medicine in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Diverse Scientific and Economic Studies, Human auditory perception and evaluation and Educational Robotics and Engineering, together about 30.8% of its articles. Its main subfields are Immunology. (generated from OpenAlex topic counts and CAS ranking data)
Research area (LetPub): MEDICINE, RESEARCH & EXPERIMENTAL
Main research topics OpenAlex counts of recent articles; shares are approximate
- Diverse Scientific and Economic StudiesEconomics, Econometrics and Finance10.5%
- Human auditory perception and evaluationEngineering10.5%
- Educational Robotics and EngineeringComputer Science9.9%
- Mast cells and histamineImmunology and Microbiology7.6%
- T-cell and B-cell ImmunologyImmunology and Microbiology4.1%
- Gut microbiota and healthBiochemistry, Genetics and Molecular Biology4.1%
- Neurogenesis and neuroplasticity mechanismsNeuroscience4.1%
- Immune Cell Function and InteractionImmunology and Microbiology4.1%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 2 |
| Minor | Medicine, Research & Experimental | Zone 2 |
Top journal: noReview journal: yes
CAS Xinrui Journal Ranking (March 2026)Medicine Zone 3
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 3 |
| Minor | Medicine, Research & Experimental | Zone 3 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 3
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 3 |
| Minor | Medicine, Research & Experimental | Zone 3 |
Top journal: noReview journal: yes
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 5.42LetPub ·
- CiteScore 2026-06
- 15LetPub ·
- SJR 2026-06
- 1.98LetPub ·
- SNIP 2026-06
- 1.9LetPub ·
- h-index
- 29OpenAlex ·
- i10-index
- 78OpenAlex ·
- 2-year mean citedness
- 3.72OpenAlex ·
- Self-citation rate
- 0%LetPub ·
- Share of gold OA articles
- 44.64%LetPub ·
Volume
- Articles per year
- 6LetPub ·
Articles by year OpenAlex count · 208 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 10 | 2 | 1 |
| 2025 | 16 | 7 | 30 |
| 2024 | 24 | 14 | 155 |
| 2023 | 53 | 40 | 648 |
| 2022 | 49 | 22 | 1,131 |
| 2021 | 36 | 16 | 705 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with PubMed · to
156 daysMedian, submission to acceptance · P25–P75 88 days – 227 days
- Acceptance to online
- median 38 days (1 articles)
- Submission to online
- median 428 days
- Sample
- 11 articles with submission and acceptance dates (13 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Hybrid open accessLetPub
A subscription journal in which authors can pay to publish their article open access.
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| OpenAlex | USD 4,650 / EUR 3,850 / GBP 3,170 | — | — |
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Profile
Publication details and official links
- Publisher
- Wiley-Blackwell
- ISSN
- 2692-9368
FAQ
Frequently asked questions about WIREs Mechanisms of Disease
What CAS zone is WIREs Mechanisms of Disease in?
In the 2025 upgraded edition of the CAS Journal Ranking, WIREs Mechanisms of Disease is in Zone 2 of Medicine, and in Zone 2 of the minor category Medicine, Research & Experimental. In the 2026 Xinrui edition it is in Zone 3 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of WIREs Mechanisms of Disease?
The latest impact factor listed by LetPub is 5.42; CiteScore 15, h-index 29.
How long does peer review take at WIREs Mechanisms of Disease?
Based on the dates recorded on 11 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 156 days (interquartile range 88–227 days). Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
Which databases index WIREs Mechanisms of Disease?
According to LetPub and DOAJ records, WIREs Mechanisms of Disease is indexed in SCIE and Scopus.
Is WIREs Mechanisms of Disease open access, and what is the APC?
WIREs Mechanisms of Disease is a hybrid journal. For open-access publication: APC about USD 4,650.
Sources and updates
The facts on this page come from LetPub, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-24). Last updated: .