Journal profile · TOXICOLOGY
Toxicology Mechanisms and Methods
ISSN 1537-6516 · eISSN 1537-6524 · Informa Healthcare · UNITED STATES · Founded 2002
Toxicology Mechanisms and Methods: CAS Zone 4 · Medicine (2025 upgraded edition); impact factor 2.99; hybrid open access; median 76 days to acceptance (98 articles, last 24 months); community-reported acceptance: easy; 110 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
Toxicology Mechanisms and Methods is published by Informa Healthcare and is in Zone 4 of Medicine in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Carcinogens and Genotoxicity Assessment, Pesticide Exposure and Toxicity and Heavy Metal Exposure and Toxicity, together about 26.9% of its articles. Its main subfields are Health, Toxicology and Mutagenesis. (generated from OpenAlex topic counts and CAS ranking data)
Toxicology Mechanisms and Methods is a peer-reviewed journal whose aim is twofold. Firstly, the journal contains original research on subjects dealing with the mechanisms by which foreign chemicals cause toxic tissue injury. Chemical substances of interest include industrial compounds, environmental pollutants, hazardous wastes, drugs, pesticides, and chemical warfare agents. The scope of the journal spans from molecular and cellular mechanisms of action to the consideration of mechanistic evidence in establishing regulatory policy. Secondly, the journal addresses aspects of the development, validation, and application of new and existing laboratory methods, techniques, and equipment. A variety of research methods are discussed, including: In vivo studies with standard and alternative species In vitro studies and alternative methodologies Molecular, biochemical, and cellular techniques Pharmacokinetics and pharmacodynamics Mathematical modeling and computer programs Forensic analyses Risk assessment Data collection and analysis.
Source: LetPub
Research area (LetPub): TOXICOLOGY
Main research topics OpenAlex counts of recent articles; shares are approximate
- Carcinogens and Genotoxicity AssessmentBiochemistry, Genetics and Molecular Biology10.4%
- Pesticide Exposure and ToxicityAgricultural and Biological Sciences10.2%
- Heavy Metal Exposure and ToxicityEnvironmental Science6.4%
- Environmental Toxicology and EcotoxicologyEnvironmental Science6.1%
- Effects and risks of endocrine disrupting chemicalsEnvironmental Science6.1%
- Drug-Induced Hepatotoxicity and ProtectionPharmacology, Toxicology and Pharmaceutics5.2%
- Nanoparticles: synthesis and applicationsMaterials Science4.6%
- Toxic Organic Pollutants ImpactEnvironmental Science4.4%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 4 |
| Minor | Toxicology | Zone 3 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Medicine Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 4 |
| Minor | Toxicology | Zone 3 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 4 |
| Minor | Toxicology | Zone 4 |
Top journal: noReview journal: no
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 2.99LetPub ·
- CiteScore 2026-06
- 5.2LetPub ·
- SJR 2026-06
- 0.64LetPub ·
- SNIP 2026-06
- 0.73LetPub ·
- h-index
- 35LetPub ·
- h-index
- 70OpenAlex ·
- i10-index
- 995OpenAlex ·
- 2-year mean citedness
- 3.06OpenAlex ·
- Self-citation rate
- 0%LetPub ·
- Share of gold OA articles
- 6.56%LetPub ·
Volume
- Articles per year
- 107LetPub ·
Articles by year OpenAlex count · 1,911 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 97 | 23 | 33 |
| 2025 | 110 | 21 | 311 |
| 2024 | 85 | 17 | 549 |
| 2023 | 70 | 11 | 518 |
| 2022 | 70 | 18 | 888 |
| 2021 | 86 | 13 | 1,469 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with Crossref · to
76 daysMedian, submission to acceptance · P25–P75 51 days – 110 days
- Acceptance to online
- median 16 days (98 articles)
- Submission to online
- median 97 days
- Sample
- 98 articles with submission and acceptance dates (215 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Average review time (community reports)
- 6–12 weeksLetPub ·
- Average acceptance (community reports)
- EasyLetPub ·
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Hybrid open accessLetPub
A subscription journal in which authors can pay to publish their article open access.
No source has fee information yet; check the journal's website.
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Profile
Publication details and official links
- Publisher
- Informa Healthcare
- Country or region
- UNITED STATES
- Language
- English
- Founded
- 2002
- ISSN
- 1537-6516
- Electronic ISSN
- 1537-6524
- Official links
- Journal homepage ↗OpenAlex
- Submission system ↗LetPub
FAQ
Frequently asked questions about Toxicology Mechanisms and Methods
What CAS zone is Toxicology Mechanisms and Methods in?
In the 2025 upgraded edition of the CAS Journal Ranking, Toxicology Mechanisms and Methods is in Zone 4 of Medicine, and in Zone 3 of the minor category Toxicology. In the 2026 Xinrui edition it is in Zone 4 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Toxicology Mechanisms and Methods?
The latest impact factor listed by LetPub is 2.99; CiteScore 5.2, h-index 70.
How long does peer review take at Toxicology Mechanisms and Methods?
Based on the dates recorded on 98 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 76 days (interquartile range 51–110 days); authors report an average review time of 6–12 weeks; the community-reported acceptance is “Easy”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
Which databases index Toxicology Mechanisms and Methods?
According to LetPub and DOAJ records, Toxicology Mechanisms and Methods is indexed in SCIE and Scopus.
Is Toxicology Mechanisms and Methods open access, and what is the APC?
Toxicology Mechanisms and Methods is a hybrid journal. Fee information is not available yet; check the journal's website.
Sources and updates
The facts on this page come from LetPub, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .