Journal profile · Physiology

Physiological Reviews

ISSN 0031-9333 · eISSN 1522-1210 · American Physiological Society · UNITED STATES · Quarterly · Founded 1921

Physiological Reviews: CAS Zone 1 · Medicine (2025 upgraded edition, Top journal); impact factor 34.66; hybrid open access; median 227 days to acceptance (80 articles, last 24 months); community-reported acceptance: mostly invited papers; 52 articles in 2025; indexed in SCIE and Scopus.

Impact factor34.66Latest value listed by LetPub
CAS zoneZone 1 · Medicine2025 upgraded edition, major category · Top journal · 2026 Xinrui edition Zone 1 · Medicine
Review time227 daysMedian, submission to acceptance · 80 articles, last 24 months · Crossref
APC—No source gives fee information
AcceptanceMostly invited papersCommunity average
Articles per year522025 · OpenAlex count

Scope

Aims, scope and focus

Physiological Reviews is published by American Physiological Society and is in Zone 1 of Medicine in the CAS Journal Ranking (2025 upgraded edition, Top journal). By OpenAlex counts of its recent articles, its largest topics are Ion channel regulation and function, Neuroscience and Neuropharmacology Research and Adipose Tissue and Metabolism, together about 25.2% of its articles. Its main subfields are Molecular Biology and Cellular and Molecular Neuroscience. (generated from OpenAlex topic counts and CAS ranking data)

e American Physiological Society (APS) is a nonprofit devoted to fostering education, scientific research, and dissemination of information in the physiological sciences. The Society was founded in 1887 with 28 members. APS now has over 10,500 members. Most members have doctoral degrees in physiology and/or medicine (or other health professions). APS is governed by an elected Council consisting of a President, President-Elect, Past President, and nine Councillors. The National headquarters of the Society is based in Rockville, Maryland. APS is a member of the Federation of American Societies for Experimental Biology (FASEB), a coalition of 26 independent societies that plays an active role in lobbying for the interests of biomedical scientists.

Source: LetPub

Research area (LetPub): Physiology

Main research topics OpenAlex counts of recent articles; shares are approximate

  1. Ion channel regulation and functionBiochemistry, Genetics and Molecular Biology9.7%
  2. Neuroscience and Neuropharmacology ResearchNeuroscience8.6%
  3. Adipose Tissue and MetabolismMedicine6.8%
  4. Neuroscience of respiration and sleepNeuroscience5.9%
  5. Ion Transport and Channel RegulationBiochemistry, Genetics and Molecular Biology5.2%
  6. Mitochondrial Function and PathologyBiochemistry, Genetics and Molecular Biology4.6%
  7. Cardiac electrophysiology and arrhythmiasMedicine4.1%
  8. Photoreceptor and optogenetics researchNeuroscience4%

Rankings & indexing

CAS ranking and database indexing

CAS Journal Ranking

CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 1
LevelCategoryZone
MajorMedicineZone 1
MinorPhysiologyZone 1

Top journal: yesReview journal: yes

CAS Xinrui Journal Ranking (March 2026)Medicine Zone 1
LevelCategoryZone
MajorMedicineZone 1
MinorPhysiologyZone 1

Top journal: yesReview journal: not marked

CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 1
LevelCategoryZone
MajorMedicineZone 1
MinorPhysiologyZone 1

Top journal: yesReview journal: yes

Database indexing

SCIEScopusLetPub

International journal early-warning lists: not listed in any editionLetPub

Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.

Metrics

Impact metrics and publication volume

Impact

Impact factor
34.66LetPub ·
CiteScore 2026-06
55.1LetPub ·
SJR 2026-06
11.49LetPub ·
SNIP 2026-06
8.44LetPub ·
h-index
312LetPub ·
h-index
565OpenAlex ·
i10-index
2,544OpenAlex ·
2-year mean citedness
23.68OpenAlex ·
Self-citation rate
0.6%LetPub ·
Share of gold OA articles
13.71%LetPub ·

Volume

Articles per year
45LetPub ·

Articles by year OpenAlex count · 2,705 in total · the current year is incomplete

YearArticlesOpen accessCitations
2026372588
202552341,169
202431251,584
202346334,252
202249387,012
202140327,354

Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.

Review & acceptance

Review time and acceptance

Review time from article dates manuscript dates registered with Crossref · to

227 daysMedian, submission to acceptance · P25–P75 177 days – 273 days

Acceptance to online
median 62 days (80 articles)
Submission to online
median 296 days
Sample
80 articles with submission and acceptance dates (108 in the window); the latest was accepted on

Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".

Other sources

Average acceptance (community reports)
Mostly invited papersLetPub ·

Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.

Fees & open access

APC and open-access policy

Hybrid open accessLetPub

A subscription journal in which authors can pay to publish their article open access.

No source has fee information yet; check the journal's website.

A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.

The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.

Profile

Publication details and official links

Publisher
American Physiological Society
Country or region
UNITED STATES
Language
English
Frequency
Quarterly
Founded
1921
ISSN
0031-9333
Electronic ISSN
1522-1210
Official links

FAQ

Frequently asked questions about Physiological Reviews

What CAS zone is Physiological Reviews in?

In the 2025 upgraded edition of the CAS Journal Ranking, Physiological Reviews is in Zone 1 of Medicine, and in Zone 1 of the minor category Physiology; it is a Top journal. In the 2026 Xinrui edition it is in Zone 1 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.

What is the impact factor of Physiological Reviews?

The latest impact factor listed by LetPub is 34.66; CiteScore 55.1, h-index 565.

How long does peer review take at Physiological Reviews?

Based on the dates recorded on 80 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 227 days (interquartile range 177–273 days); the community-reported acceptance is “Mostly invited papers”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.

Which databases index Physiological Reviews?

According to LetPub and DOAJ records, Physiological Reviews is indexed in SCIE and Scopus.

Is Physiological Reviews open access, and what is the APC?

Physiological Reviews is a hybrid journal. Fee information is not available yet; check the journal's website.

Sources and updates

The facts on this page come from LetPub, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .