Journal profile · PHYSIOLOGY
Comprehensive Physiology
ISSN 2040-4603 · Wiley-Blackwell · UNITED STATES
Comprehensive Physiology: CAS Zone 2 · Medicine (2025 upgraded edition); impact factor 5.94; hybrid open access; median 98 days to acceptance (104 articles, last 24 months); community-reported acceptance: easy; 94 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
Comprehensive Physiology is published by Wiley-Blackwell and is in Zone 2 of Medicine in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Adipose Tissue and Metabolism, Neuroscience of respiration and sleep and Pancreatic function and diabetes, together about 23.3% of its articles. Its main subfields are Physiology. (generated from OpenAlex topic counts and CAS ranking data)
Oversight of the ongoing editorial and scientific development of Comprehensive Physiology is provided by a distinguished Editorial Advisory Board (EAB) sponsored by the American Physiological Society and chaired by Editor-in-Chief Y. S. Prakash. The EAB in turn recruits a world-class team of Topic Editors who assign articles and recruit authors. For a full listing of Editors, go to the Editors page.
From the journal's Aims & Scope
Research area (LetPub): PHYSIOLOGY
Editor-in-chief Y. S. Prakash.Publisher website
Main research topics OpenAlex counts of recent articles; shares are approximate
- Adipose Tissue and MetabolismMedicine9%
- Neuroscience of respiration and sleepNeuroscience8.5%
- Pancreatic function and diabetesMedicine5.7%
- Heart Rate Variability and Autonomic ControlMedicine5.5%
- Diet and metabolism studiesMedicine5.1%
- Ion channel regulation and functionBiochemistry, Genetics and Molecular Biology4.8%
- Muscle metabolism and nutritionBiochemistry, Genetics and Molecular Biology4.6%
- Ion Transport and Channel RegulationBiochemistry, Genetics and Molecular Biology4.5%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 2 |
| Minor | Physiology | Zone 1 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Medicine Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 2 |
| Minor | Physiology | Zone 1 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 2 |
| Minor | Physiology | Zone 1 |
Top journal: noReview journal: no
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Indexing the journal's website claims
MEDLINEPubMedPublisher website
As the journal's website lists them, not checked against each database; for Web of Science editions the records above apply.
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 5.94LetPub ·
- Impact factor (publisher) 2018
- 6.25Publisher website ·
- CiteScore 2026-06
- 8.6LetPub ·
- SJR 2026-06
- 2.06LetPub ·
- SNIP 2026-06
- 1.65LetPub ·
- h-index
- 58LetPub ·
- h-index
- 187OpenAlex ·
- i10-index
- 1,566OpenAlex ·
- 2-year mean citedness
- 2.86OpenAlex ·
- Self-citation rate
- 0%LetPub ·
- Share of gold OA articles
- 31.82%LetPub ·
Volume
- Articles per year
- 78LetPub ·
Articles by year OpenAlex count · 3,897 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 190 | 92 | 159 |
| 2025 | 94 | 58 | 584 |
| 2024 | 49 | 16 | 209 |
| 2023 | 88 | 36 | 887 |
| 2022 | 86 | 20 | 1,159 |
| 2021 | 122 | 33 | 1,949 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with Crossref · to
98 daysMedian, submission to acceptance · P25–P75 61 days – 132 days
- Acceptance to online
- median 12 days (104 articles)
- Submission to online
- median 111 days
- Sample
- 104 articles with submission and acceptance dates (276 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Average review time (community reports)
- 6–12 weeksLetPub ·
- Average acceptance (community reports)
- EasyLetPub ·
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Hybrid open accessLetPub
A subscription journal in which authors can pay to publish their article open access.
No source has fee information yet; check the journal's website.
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
Article types accepted1
- overview articlesAll new and updated articles currently being commissioned for Comprehensive Physiology are defined as Overview articles.Length not stated
Policy excerpts from the journal's websitePublication ethics, Self-archiving
- Publication ethics
Adheres to COPE guidelines; publishing misconduct will result in rejection/retraction. Model summary
Comprehensive Physiology adheres strongly to the guidelines of the Committee on Publication Ethics (COPE).
Source ↗Publisher website ·- Self-archiving
NIH-funded authors may upload accepted manuscript to PubMedCentral, made public 12 months after publication. Model summary
Comprehensive Physiology authors may upload the accepted manuscript version (not the published article) to PubMedCentral (PMC) if the work described in the article was supported by NIH funding and that fact is acknowledged explicitly in the article.
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- Wiley-Blackwell
- Country or region
- UNITED STATES
- Language
- English
- ISSN
- 2040-4603
- Society / sponsor
- American Physiological Society Learn more at www
- Official links
- Journal homepage ↗OpenAlex
- Submission system ↗Publisher website
FAQ
Frequently asked questions about Comprehensive Physiology
What CAS zone is Comprehensive Physiology in?
In the 2025 upgraded edition of the CAS Journal Ranking, Comprehensive Physiology is in Zone 2 of Medicine, and in Zone 1 of the minor category Physiology. In the 2026 Xinrui edition it is in Zone 2 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Comprehensive Physiology?
The latest impact factor listed by LetPub is 5.94; CiteScore 8.6, h-index 187.
How long does peer review take at Comprehensive Physiology?
Based on the dates recorded on 104 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 98 days (interquartile range 61–132 days); authors report an average review time of 6–12 weeks; the community-reported acceptance is “Easy”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
Which databases index Comprehensive Physiology?
According to LetPub and DOAJ records, Comprehensive Physiology is indexed in SCIE and Scopus. The journal's website also lists MEDLINE and PubMed; that list has not been checked against each database.
Is Comprehensive Physiology open access, and what is the APC?
Comprehensive Physiology is a hybrid journal. Fee information is not available yet; check the journal's website.
Sources and updates
The facts on this page come from LetPub, OpenAlex, Publisher website; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .