Journal profile · Biochemistry, Genetics and Molecular Biology-Endocrinology
Molecular Genetics and Metabolism Reports
ISSN 2214-4269 · Elsevier · Netherlands
Molecular Genetics and Metabolism Reports: CAS Zone 4 · Medicine (2025 upgraded edition); impact factor 1.75; fully open access; APC about USD 2,620; median 94 days to acceptance (107 articles, last 24 months); 98 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
Molecular Genetics and Metabolism Reports is published by Elsevier and is in Zone 4 of Medicine in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Metabolism and Genetic Disorders, Lysosomal Storage Disorders Research and Mitochondrial Function and Pathology, together about 43% of its articles. (generated from OpenAlex topic counts and CAS ranking data)
Molecular Genetics and Metabolism Reports is a peer-reviewed Gold Open Access journal dedicated to advancing the understanding of inborn metabolic diseases and metabolic dysfunction in Mendelian conditions through innovative research in molecular genetics and metabolic pathways. As its companion title Molecular Genetics and Metabolism, the journal is committed to publishing high-quality research.The journal welcomes original full-length research articles, short communication (single point, single figure article), case reports of significant interest, case series (several cases with the same diagnosis), reviews, and letters to the editor. Submissions may involve human patients, animal models, cellular systems, and computational frameworks.The journal mainly considers articles on translational and clinical investigations, including:Advances in metabolic engineering, gene therapy, and personalized medicine, including novel therapeutic approaches.Evaluation of drug delivery systems and gene editing technologies.Long-term follow-up studies on the efficacy and safety of gene and enzyme replacement therapies.Clinical trials and longitudinal studies assessing early interventions and treatment strategies.Comparative effectiveness research of existing therapies and interventions.Patient-centered research focused on management, quality of life, and healthcare needs.Clinical guidelines and treatment protocols for inherited metabolic diseases.Development and validation of novel methods in newborn screening and diagnostic approaches.Discovery and validation of biochemical markers for early diagnosis and prognosis of inherited metabolic diseases.Characterization of new phenotypes and novel genetic disorders.Research on epigenetic influences, microbiome interactions, and nutritional genomics.Integration of multi-omics data for comprehensive disease modeling and therapy development.Implementation of pharmacogenomics and precision medicine for optimizing treatments.Advances in telemedicine and digital health for managing inherited metabolic diseases.Assessment of mental health and cognitive outcomes in patients with inherited metabolic disorders.Ethical, legal, and social implications (ELSI) of genetic testing and interventions.While the journal primarily focuses on translational and clinical research, basic research articles may be considered in some instances.Studies primarily focused on acquired metabolic conditions, such as metabolic syndrome, obesity, lifestyle-associated metabolic disorders, non-inherited cancers, or other multifactorial metabolic diseases, are outside the scope of the journal.Authors are also encouraged to submit to the journal’s companion title, Molecular Genetics and Metabolism, which welcomes high-quality studies on the fundamental mechanisms of inherited metabolic diseases in addition to translational studies.
From the journal's Aims & Scope
Research area (LetPub): Biochemistry, Genetics and Molecular Biology-Endocrinology
Editor-in-chief Kimberly ChapmanPublisher website
Editorial board by country: none in mainland China; most named United States 23, Canada 5, Japan 4, Taiwan, China 2, Spain 2 (43 members with a country) Editorial board ↗Publisher website ·
Main research topics OpenAlex counts of recent articles; shares are approximate
- Metabolism and Genetic DisordersBiochemistry, Genetics and Molecular Biology18.9%
- Lysosomal Storage Disorders ResearchMedicine16.1%
- Mitochondrial Function and PathologyBiochemistry, Genetics and Molecular Biology8%
- Glycogen Storage Diseases and MyoclonusMedicine7.7%
- Trypanosoma species research and implicationsMedicine4.8%
- Folate and B Vitamins ResearchMedicine4.6%
- Genomics and Rare DiseasesBiochemistry, Genetics and Molecular Biology4.4%
- Carbohydrate Chemistry and SynthesisChemistry3.8%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 4 |
| Minor | Genetics & Heredity | Zone 3 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Medicine Zone 3
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 3 |
| Minor | Genetics & Heredity | Zone 3 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 4 |
| Minor | Genetics & Heredity | Zone 4 |
Top journal: noReview journal: no
Database indexing
SCIEScopusDOAJLetPub
International journal early-warning lists: not listed in any editionLetPub
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 1.75LetPub ·
- Impact factor (publisher)
- 1.8Publisher website ·
- CiteScore 2026-06
- 3.1LetPub ·
- CiteScore (publisher)
- 3.1Publisher website ·
- SJR 2026-06
- 0.61LetPub ·
- SNIP 2026-06
- 0.89LetPub ·
- h-index
- 41OpenAlex ·
- i10-index
- 481OpenAlex ·
- 2-year mean citedness
- 1.25OpenAlex ·
- Self-citation rate
- 5.6%LetPub ·
- Share of gold OA articles
- 100%LetPub ·
Volume
- Articles per year
- 94LetPub ·
Articles by year OpenAlex count · 1,362 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 80 | 80 | 6 |
| 2025 | 98 | 98 | 76 |
| 2024 | 136 | 136 | 311 |
| 2023 | 94 | 94 | 449 |
| 2022 | 106 | 106 | 801 |
| 2021 | 138 | 138 | 1,338 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with PubMed · to
94 daysMedian, submission to acceptance · P25–P75 65 days – 133 days
- Acceptance to online
- median 7 days (107 articles)
- Submission to online
- median 102 days
- Sample
- 107 articles with submission and acceptance dates (229 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Average review time (community reports)
- about 8 weeksLetPub ·
- Submission to first decision
- 3 daysPublisher website ·
- First decision after review
- 57 daysPublisher website ·
- Submission to acceptance
- 95 daysPublisher website ·
- Acceptance to publication
- 7 daysPublisher website ·
- Submission to publication (journal-reported)
- about 15 weeksDOAJ ·
- Peer review
- Single anonymous peer reviewDOAJ
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Fully open accessDOAJ
Every article is open access; authors usually pay an article processing charge (APC).
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| DOAJ | USD 2,620 | Yes | CC BY, CC BY-NC, CC BY-NC-ND | |
| OpenAlex | USD 2,400 / EUR 2,250 / GBP 1,920 / JPY 297,670 | — | — | |
| LetPub | USD 2,410 | Yes | — | |
| Publisher website | USD 2,820 | — | — |
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
What to prepare4 items from the author guidelines
- Abstract
- ≤ 250 words
- Keywords
- 1–7
- Reference style
- Numbered, in order of citation
- Highlights
- Optional
Article types accepted12
- brief communicationIn addition to original research articles, occasional minireviews reporting timely advances as well as brief communications and letters to the editor are consid…Length not stated
- brief reportIn addition to original research articles, occasional minireviews reporting timely advances as well as brief communications and letters to the editor are consid…Length not stated
- brief reportsBrief Reports are communications considered for publication with an expedited review. These short manuscripts should be no more than 5 manuscript pages (approxi…Length not stated
- commentaryIn addition to original research articles, occasional minireviews reporting timely advances as well as brief communications and letters to the editor are consid…Length not stated
- editorialIn addition to original research articles, occasional minireviews reporting timely advances as well as brief communications and letters to the editor are consid…Length not stated
- letters to the editorIn addition to original research articles, occasional minireviews reporting timely advances as well as brief communications and letters to the editor are consid…Length not stated
- minireviewsMinireviews will describe timely advances within the scope of the journal, emphasizing emerging topical areas and/or critically analyzing existing data.Length not stated
- original articleIn addition to original research articles, occasional minireviews reporting timely advances as well as brief communications and letters to the editor are consid…Length not stated
- original research articleIn addition to original research articles, occasional minireviews reporting timely advances as well as brief communications and letters to the editor are consid…Length not stated
- original research articlesMolecular and Metabolic Reports are original research articles that will be considered on the basis of the originality and quality of the work, the clarity of t…Length not stated
- reviewIn addition to original research articles, occasional minireviews reporting timely advances as well as brief communications and letters to the editor are consid…Length not stated
- sequence reportsSequence Reports are detailed descriptions of sequencing observations without functional data.Length not stated
Policy excerpts from the journal's websiteAI use, Authorship, Conflicts of interest, Data availability, Publication ethics, License & copyright, Open access, Peer review, Preprints
- AI use Declaration of generative AI use
Authors must declare the use of generative AI tools in the manuscript preparation process upon submission of the paper.Generative AI and AI-assisted technologies (“AI tools”) have been rapidly adopted in research and scholarly publishing, offering significant benefits while requiring clear standards for responsible and transparent use.Authors preparing a manuscript for this journal may use AI tool…
Source ↗Publisher website ·- Authorship Group authorship
1 to 7 keywords required Model summary
Group authorship refers to the attribution of an article to a defined and named group of authors whose members have contributed to the work. Examples include research consortia, clinical trial groups, collaborative networks, task forces or working groups, expert panels or consensus groups, and participatory research groups. Group authorship must be declared on the title page at submission. When av…
Source ↗Publisher website ·- Conflicts of interest Declaration of competing interests
All authors must disclose any financial and personal relationships with other people or organizations that could inappropriately influence or bias their work. Examples of potential competing interests include:EmploymentConsultanciesStock ownershipHonorariaPaid expert testimonyPatent applications or registrationsGrants or any other fundingAffiliation with the journal as an Editor or Advisory Board …
Source ↗Publisher website ·- Data availability
Data statement required Model summary
To foster transparency, you are required to state the availability of any data at submission.
Source ↗Publisher website ·- Publication ethics
Publishing ethics policy Model summary
Authors must follow ethical guidelines stated in Elsevier's Publishing Ethics Policy.
Source ↗Publisher website ·- License & copyright License options
Authors will be offered open access user license options which will determine how you, and third parties, can reuse your open access article. We advise that you review these options and any funding body license requirements before selecting a license option.
Source ↗Publisher website ·- Open access Open access
We refer you to our open access information page to learn about open access options for this journal.
Source ↗Publisher website ·- Peer review Peer review
Single anonymized review process Model summary
This journal follows a single anonymized review process. Your submission will initially be assessed by our editors. If your submission is deemed suitable, it will typically be sent to be reviewed by a minimum of two reviewers for an independent expert assessment of the scientific quality. The decision as to whether your article is accepted or rejected for publication will be made by our editors.Re…
Source ↗Publisher website ·- Preprints Preprints
Preprint sharing allowed Model summary
Preprint sharingAuthors may share preprints in line with Elsevier's article sharing policy. Sharing preprints, such as on a preprint server, will not count as prior publication.We advise you to read our policy on multiple, redundant or concurrent publication. In support of Open Science, this journal offers its authors a free preprint posting service on SSRN, Elsevier’s preprint and early research …
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- Elsevier
- Country or region
- Netherlands
- Language
- English
- ISSN
- 2214-4269
- Society / sponsor
- Society for Inherited Metabolic Disorders
- Official links
- Journal homepage ↗DOAJ
- Submission system ↗Publisher website
- Author guidelines ↗DOAJ
- Aims & Scope ↗DOAJ
- Special issues ↗Publisher website
- APC information ↗DOAJ
- Fee waivers ↗DOAJ
- Open access statement ↗DOAJ
- License & copyright ↗DOAJ
- Peer review process ↗DOAJ
- Editorial board ↗DOAJ
- Plagiarism policy ↗DOAJ
FAQ
Frequently asked questions about Molecular Genetics and Metabolism Reports
What CAS zone is Molecular Genetics and Metabolism Reports in?
In the 2025 upgraded edition of the CAS Journal Ranking, Molecular Genetics and Metabolism Reports is in Zone 4 of Medicine, and in Zone 3 of the minor category Genetics & Heredity. In the 2026 Xinrui edition it is in Zone 3 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Molecular Genetics and Metabolism Reports?
The latest impact factor listed by LetPub is 1.75; CiteScore 3.1, h-index 41.
How long does peer review take at Molecular Genetics and Metabolism Reports?
Based on the dates recorded on 107 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 94 days (interquartile range 65–133 days); authors report an average review time of about 8 weeks. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
What are the manuscript requirements of Molecular Genetics and Metabolism Reports?
According to the journal's author guidelines: Abstract: ≤ 250 words; Keywords: 1–7; Reference style: Numbered, in order of citation; Highlights: Optional. A model extracted these from the author guidelines and each was checked against the text; check the latest version on the journal's website before submitting.
Where are the editorial board members of Molecular Genetics and Metabolism Reports based?
Of the 43 board members whose country the journal's board page names, none are in mainland China; the countries named most often are United States (23), Canada (5) and Japan (4). Counted from the institutions listed on the board page; for reference only.
Which databases index Molecular Genetics and Metabolism Reports?
According to LetPub and DOAJ records, Molecular Genetics and Metabolism Reports is indexed in SCIE, Scopus and DOAJ.
Is Molecular Genetics and Metabolism Reports open access, and what is the APC?
Molecular Genetics and Metabolism Reports is a fully open-access journal. APC about USD 2,620.
Sources and updates
The facts on this page come from LetPub, Publisher website, OpenAlex, DOAJ; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-26). Last updated: .