Journal profile · Genetics & Heredity
Human Mutation
ISSN 1059-7794 · eISSN 1098-1004 · Wiley-Liss Inc. · UNITED STATES · Monthly · Founded 1992
Human Mutation: CAS Zone 2 · Medicine (2025 upgraded edition); impact factor 1.81; fully open access; APC about USD 2,740; median 150 days to acceptance (122 articles, last 24 months); community-reported acceptance: about 50%; 99 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
Human Mutation is published by Wiley-Liss Inc. and is in Zone 2 of Medicine in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Genomics and Rare Diseases, Genomic variations and chromosomal abnormalities and Metabolism and Genetic Disorders, together about 23.5% of its articles. Its main subfields are Genetics and Molecular Biology. (generated from OpenAlex topic counts and CAS ranking data)
Human Mutation is a peer-reviewed journal that offers publication of original research & reviews on broad aspects of mutation research in humans. Reports of novel DNA variations and their phenotypic consequences, reports of SNPs demonstrated as valuable for genomic analysis, descriptions of new molecular detection methods, and novel approaches to clinical diagnosis are welcomed. Novel reports of gene organization at the genomic level, reported in the context of mutation investigation, may be considered. The journal provides a unique forum for the exchange of ideas, methods, and applications of interest to molecular, human, and medical geneticists in academic, industrial, and clinical research settings worldwide. Sections include: Methodology Gene function Databases and bioinformatic tools Gene and phenotype Diagnostics
From the journal's Aims & Scope
Research area (LetPub): Genetics & Heredity
Editor-in-chief Miklos Sahin-TothPublisher website
Editorial board by country: 2 in mainland China (about 13%); most named United States 3, Mainland China 2, India 2, France 2, Taiwan, China 1 (16 members with a country) Editorial board ↗Publisher website ·
Main research topics OpenAlex counts of recent articles; shares are approximate
- Genomics and Rare DiseasesBiochemistry, Genetics and Molecular Biology10.1%
- Genomic variations and chromosomal abnormalitiesBiochemistry, Genetics and Molecular Biology7%
- Metabolism and Genetic DisordersBiochemistry, Genetics and Molecular Biology6.3%
- Cancer Genomics and DiagnosticsBiochemistry, Genetics and Molecular Biology6%
- RNA modifications and cancerBiochemistry, Genetics and Molecular Biology5.9%
- RNA and protein synthesis mechanismsBiochemistry, Genetics and Molecular Biology5.2%
- Genetic factors in colorectal cancerMedicine4.8%
- RNA Research and SplicingBiochemistry, Genetics and Molecular Biology4.7%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 2 |
| Minor | Genetics & Heredity | Zone 2 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Medicine Zone 3
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 3 |
| Minor | Genetics & Heredity | Zone 2 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 2 |
| Minor | Genetics & Heredity | Zone 2 |
Top journal: noReview journal: no
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Indexing the journal's website claims
ESCIMEDLINEPubMedEmbaseCASPublisher website
Other: ProQuest
As the journal's website lists them, not checked against each database; for Web of Science editions the records above apply.
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 1.81LetPub ·
- Impact factor (publisher)
- 1.8Publisher website ·
- Impact factor (publisher) 2025
- 1.8Publisher website ·
- CiteScore 2026-06
- 8.7LetPub ·
- CiteScore (publisher)
- 8.7Publisher website ·
- CiteScore (publisher) 2025
- 8.7Publisher website ·
- SJR 2026-06
- 1.97LetPub ·
- SNIP 2026-06
- 1.56LetPub ·
- h-index
- 146LetPub ·
- h-index
- 220OpenAlex ·
- i10-index
- 5,247OpenAlex ·
- 2-year mean citedness
- 0.91OpenAlex ·
- Self-citation rate
- 0%LetPub ·
- Share of gold OA articles
- 99.4%LetPub ·
Volume
- Articles per year
- 94LetPub ·
- Articles per year (publisher) 2025
- 94Publisher website ·
- Downloads per year (publisher) 2025
- 774,038Publisher website ·
Articles by year OpenAlex count · 8,142 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 279 | 278 | 51 |
| 2025 | 99 | 98 | 166 |
| 2024 | 39 | 38 | 162 |
| 2023 | 34 | 34 | 216 |
| 2022 | 184 | 143 | 3,147 |
| 2021 | 173 | 127 | 3,490 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with Crossref · to
150 daysMedian, submission to acceptance · P25–P75 99 days – 256 days
- Acceptance to online
- median 27 days (122 articles)
- Submission to online
- median 178 days
- Sample
- 122 articles with submission and acceptance dates (368 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Average review time (community reports)
- about 3 monthsLetPub ·
- Average acceptance (community reports)
- 50%LetPub ·
- Acceptance rate (publisher)
- 23%Publisher website ·
- Acceptance rate (publisher) 2025
- 23%Publisher website ·
- Submission to first decision
- 29 daysPublisher website ·
- Submission to first decision 2025
- 29 daysPublisher website ·
- Submission to acceptance 2025
- 118 daysPublisher website ·
- Acceptance to publication 2025
- 31 daysPublisher website ·
- Peer review
- Single anonymous peer reviewPublisher website
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Fully open accessLetPub
Every article is open access; authors usually pay an article processing charge (APC).
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| OpenAlex | USD 2,740 / EUR 2,380 / GBP 2,010 | — | — | |
| Publisher website | Yes, amount not published | — | — |
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
What to prepare2 items from the author guidelines
- Reference style
- Chicago
- Not considered
- Case Report
Article types accepted17, with length limits
- case reportThe journal will consider the following article types: Research articles Research articles should present the results of an original research study. These manus…Length not stated
- commentaryThe journal will consider the following article types: Research articles Research articles should present the results of an original research study. These manus…Length not stated
- editorialThe journal will consider the following article types: Research articles Research articles should present the results of an original research study. These manus…Length not stated
- letterThe journal will consider the following article types: Research articles Research articles should present the results of an original research study. These manus…Length not stated
- letter to the editorThe journal will consider the following article types: Research articles Research articles should present the results of an original research study. These manus…main text ≤ 600 words
- letters to the editorThe journal will consider the following article types: Research articles Research articles should present the results of an original research study. These manus…Length not stated
- meta-analysisThe journal will consider the following article types: Research articles Research articles should present the results of an original research study. These manus…Length not stated
- original researchThe journal will consider the following article types: Research articles Research articles should present the results of an original research study. These manus…Length not stated
- perspectiveThe journal will consider the following article types: Research articles Research articles should present the results of an original research study. These manus…Length not stated
- research articleThe journal will consider the following article types: Research articles Research articles should present the results of an original research study. These manus…Length not stated
- research articlesResearch articles should present the results of an original research study. These manuscripts should describe how the research project was conducted and provide…Length not stated
- research letterAbstracts are limited to 100 words. The main text should not exceed 1,000 words and should not include subheadings. A maximum of 2 figures or tables (combined) …Length not stated
- reviewThe journal will consider the following article types: Research articles Research articles should present the results of an original research study. These manus…Length not stated
- review articleThe journal will consider the following article types: Research articles Research articles should present the results of an original research study. These manus…Length not stated
- reviewsA review article provides an overview of the published literature in a particular subject area.Length not stated
- systematic reviewThe journal will consider the following article types: Research articles Research articles should present the results of an original research study. These manus…Length not stated
- systematic review and meta-analysisSubmissions should generally include original data analyzed in the context of the published literature. If no original data are included, authors are advised to…Length not stated
Policy excerpts from the journal's websiteAI use, Authorship, Conflicts of interest, Data availability, License & copyright, Peer review, Plagiarism, Preprints, Trial registration / reporting guidelines
- AI use
Human Mutation provides a unique forum for the exchange of ideas, methods, and applications of interest to molecular, human, and medical geneticists in academic, industrial, and clinical research settings worldwide. Model summary
Human Mutation provides a unique forum for the exchange of ideas, methods, and applications of interest to molecular, human, and medical geneticists in academic, industrial, and clinical research settings worldwide.
Source ↗Publisher website ·- Authorship Title and authorship information
The following information should be included: Manuscript title Full author names Full institutional mailing addresses Email addresses Affiliations. The publisher remains neutral with regard to jurisdictional claims in institutional affiliations. Responsibility for affiliations ultimately rests with the author, although the publisher may request changes be made to countries listed in affiliations t…
Source ↗Publisher website ·- Conflicts of interest Conflicts of interest
Concurrent submissions Model summary
Authors must declare all relevant interests that could be perceived as conflicting. Authors should explain why each interest may represent a conflict. If no conflicts exist, the authors should state this. Submitting authors are responsible for co-authors declaring their interests. Conflicts of interest (COIs, also known as 'competing interests') occur when issues outside research could be reasonab…
Source ↗Publisher website ·- Data availability Data availability
Data availability statement Model summary
Authors must include a data availability statement with their submission. When submitting a manuscript, submitting authors will be asked to select from several pre-written statements or use the text editor to tell us about data availability with regard to their submission. Review our Data Sharing Policy to understand which data availability statement is right for your submission.
Source ↗Publisher website ·- License & copyright Copyright and permissions
Copyright policy Model summary
Authors retain the copyright of their manuscripts, and all open access articles are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited. The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not speci…
Source ↗Publisher website ·- Peer review Peer review
Peer review model Model summary
The journal follows a single-anonymized peer review model, for applicable article types. Information on the Peer Review model can be found here. Wiley's policy on the confidentiality of the review process is available here. All submitted articles are subject to assessment and peer review to ensure editorial appropriateness and technical correctness. Research published in the journal must be: Scien…
Source ↗Publisher website ·- Plagiarism
Plagiarism detection Model summary
This journal uses iThenticate’s CrossCheck software to detect instances of overlapping and similar text in submitted manuscripts.
Source ↗Publisher website ·- Preprints Preprints
Preprint policy Model summary
The journal accepts articles previously published on preprint servers, and does not consider this to compromise the novelty of the results. Articles based on content previously made public only on a preprint server, institutional repository, or in a thesis will be considered. The preprint should be cited.
Source ↗Publisher website ·- Trial registration / reporting guidelines Reporting guidelines
Authors are strongly encouraged to use appropriate reporting guidelines when preparing and submitting manuscripts, to maximize transparency and reproducibility. Our editors and reviewers are also encouraged to use them in the review process. Completed checklists should be provided in the supplementary files on submission. We particularly encourage the use of: CONSORT for randomized controlled tria…
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- Wiley-Liss Inc.
- Country or region
- UNITED STATES
- Language
- English
- Frequency
- Monthly
- Founded
- 1992
- ISSN
- 1059-7794
- Electronic ISSN
- 1098-1004
- Official links
- Journal homepage ↗OpenAlex
- Submission system ↗LetPub
- Author guidelines ↗LetPub
- Special issues ↗Publisher website
FAQ
Frequently asked questions about Human Mutation
What CAS zone is Human Mutation in?
In the 2025 upgraded edition of the CAS Journal Ranking, Human Mutation is in Zone 2 of Medicine, and in Zone 2 of the minor category Genetics & Heredity. In the 2026 Xinrui edition it is in Zone 3 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Human Mutation?
The latest impact factor listed by LetPub is 1.81; CiteScore 8.7, h-index 220.
How long does peer review take at Human Mutation?
Based on the dates recorded on 122 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 150 days (interquartile range 99–256 days); authors report an average review time of about 3 months; the community-reported acceptance is “about 50%”; the journal's website gives an acceptance rate of 23% (2025). Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
Where are the editorial board members of Human Mutation based?
Of the 16 board members whose country the journal's board page names, 2 (about 13%) are in mainland China; the countries named most often are United States (3), Mainland China (2) and India (2). Counted from the institutions listed on the board page; for reference only.
Which databases index Human Mutation?
According to LetPub and DOAJ records, Human Mutation is indexed in SCIE and Scopus. The journal's website also lists ESCI, MEDLINE, PubMed, Embase and CAS; that list has not been checked against each database.
Is Human Mutation open access, and what is the APC?
Human Mutation is a fully open-access journal. APC about USD 2,740.
Sources and updates
The facts on this page come from LetPub, Publisher website, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .