Journal profile · Biochemistry & Molecular Biology

Current Opinion in Structural Biology

ISSN 0959-440X · eISSN 1879-033X · Elsevier Ltd · ENGLAND · Bimonthly · Founded 1991

Current Opinion in Structural Biology: CAS Zone 2 · Biology (2025 upgraded edition, Top journal); impact factor 7.69; hybrid open access; APC about USD 4,360; median 90 days to acceptance (108 articles, last 24 months); community-reported acceptance: fairly hard; 193 articles in 2025; indexed in SCIE and Scopus.

Impact factor7.69Latest value listed by LetPub
CAS zoneZone 2 · Biology2025 upgraded edition, major category · Top journal · 2026 Xinrui edition Zone 2 · Biology
Review time90 daysMedian, submission to acceptance · 108 articles, last 24 months · PubMed
APCUSD 4,360Hybrid journal: charged only for open-access articles
AcceptanceFairly hardCommunity average
Articles per year1932025 · OpenAlex count

Scope

Aims, scope and focus

Current Opinion in Structural Biology is published by Elsevier Ltd and is in Zone 2 of Biology in the CAS Journal Ranking (2025 upgraded edition, Top journal). By OpenAlex counts of its recent articles, its largest topics are Protein Structure and Dynamics, RNA and protein synthesis mechanisms and Enzyme Structure and Function, together about 39.1% of its articles. Its main subfields are Molecular Biology. (generated from OpenAlex topic counts and CAS ranking data)

Current Opinion in Structural Biology aims to stimulate scientifically grounded, interdisciplinary, multi-scale debate and exchange of ideas. It contains polished, concise and timely reviews and opinions, with particular emphasis on those articles published in the past two years. In addition to describing recent trends, the authors are encouraged to give their subjective opinion of the topics discussed.In COSB, we help the reader by providing in a systematic manner:1. The views of experts on current advances in their field in a clear and readable form. 2. Evaluations of the most interesting papers, annotated by experts, from the great wealth of original publications.COSB will serve as an invaluable source of information for researchers, lecturers, teachers, professionals, policy makers and students.Division of the subject into sectionsThe subject of Structural Biology is divided into thirteen themed sections, each of which is reviewed once a year. Folding, Binding, and Protein Design AI Methodologies in Structural Biology Theory and Simulation/Computational Methods Macromolecular Assemblies New Concepts in Drug Discovery Single Molecule and Macromolecular Dynamics 3D Genome and Subcellular Organization Membranes and Membrane Proteins Cryo-EM Biophysical Methods Protein-Nucleic Acid Interactions Catalysis and Regulation Single Cell and Cell-Cell Interactions Selection of topics to be reviewedGuest Editors, who are major authorities in the field, are appointed by the Editors of the journal. They divide their section into a number of topics, ensuring that the field is comprehensively covered and that all issues of current importance are emphasised. Guest Editors commission reviews from authorities on each topic that they have selected. The Editorial Board provides support to the Editors and the Guest Editors with their comments and suggestions on names and topics.Review articles in COSB are by invitation only. The journal does not accept manuscripts other from those invited by guest editors, appointed by Editors-in-Chief.Review ArticlesThe Current Opinion journals were developed out of the recognition that it is increasingly difficult for specialists to keep up to date with the expanding volume of information published in their subject. In the Current Opinion journals, we help the reader by providing in a systematic manner: (1) The views of experts on current advances in the field in a clear and readable form. (2) Evaluations of the most interesting papers, annotated by experts, from the great wealth of original publications. The aim of the manuscript is to review recent articles, with particular emphasis on those articles published in the past two years. In addition to describing recent trends, you are encouraged to give your subjective opinion of the topics discussed, although you should not concentrate unduly on your own research. Your review should be approximately 2000 words (not including references or reference notes), with approximately 50 references and, as such, the review is intended to be a concise view of the field as it is at the moment, rather than a comprehensive overview. Our audience ranges from student to professor, so articles must be accessible to a wide readership. Please avoid jargon, but do not oversimplify: be accurate and precise throughout. Occasionally, unpublished data can be referred to, but only when essential and should never be used to substantiate any significant point. Editorial OverviewSection Editors write a short overview at the beginning of the section to introduce the reviews and to draw the reader's attention to any particularly interesting developments. This successful format has made COSB one of the most highly regarded review journals in the field.Please see further information under writing and formatting – additional information.

From the journal's Aims & Scope

Research area (LetPub): Biochemistry & Molecular Biology

Editor-in-chief Ruth NussinovPublisher website

Editorial board by country: 3 in mainland China (about 6%); most named United Kingdom 13, United States 12, Germany 5, Mainland China 3, Switzerland 3 (49 members with a country) Editorial board ↗Publisher website ·

Main research topics OpenAlex counts of recent articles; shares are approximate

  1. Protein Structure and DynamicsBiochemistry, Genetics and Molecular Biology15.5%
  2. RNA and protein synthesis mechanismsBiochemistry, Genetics and Molecular Biology13.6%
  3. Enzyme Structure and FunctionMaterials Science10.1%
  4. Glycosylation and Glycoproteins ResearchBiochemistry, Genetics and Molecular Biology4.6%
  5. RNA Research and SplicingBiochemistry, Genetics and Molecular Biology4.5%
  6. RNA modifications and cancerBiochemistry, Genetics and Molecular Biology4.4%
  7. DNA and Nucleic Acid ChemistryBiochemistry, Genetics and Molecular Biology3.7%
  8. Photosynthetic Processes and MechanismsBiochemistry, Genetics and Molecular Biology3.3%

Rankings & indexing

CAS ranking and database indexing

CAS Journal Ranking

CAS Journal Ranking, upgraded edition (March 2025)Biology Zone 2
LevelCategoryZone
MajorBiologyZone 2
MinorBiochemistry & Molecular BiologyZone 2
MinorCell BiologyZone 2

Top journal: yesReview journal: yes

CAS Xinrui Journal Ranking (March 2026)Biology Zone 2
LevelCategoryZone
MajorBiologyZone 2
MinorBiochemistry & Molecular BiologyZone 2
MinorCell BiologyZone 2

Top journal: yesReview journal: not marked

CAS Journal Ranking, previous upgraded edition (December 2023)Biology Zone 2
LevelCategoryZone
MajorBiologyZone 2
MinorBiochemistry & Molecular BiologyZone 2
MinorCell BiologyZone 2

Top journal: yesReview journal: yes

Database indexing

SCIEScopusLetPub

International journal early-warning lists: not listed in any editionLetPub

Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.

Metrics

Impact metrics and publication volume

Impact

Impact factor
7.69LetPub ·
Impact factor (publisher)
7.8Publisher website ·
CiteScore 2026-06
13.7LetPub ·
CiteScore (publisher)
13.7Publisher website ·
SJR 2026-06
2.96LetPub ·
SNIP 2026-06
1.61LetPub ·
h-index
190LetPub ·
h-index
255OpenAlex ·
i10-index
3,531OpenAlex ·
2-year mean citedness
8.36OpenAlex ·
Self-citation rate
3.8%LetPub ·
Share of gold OA articles
55.11%LetPub ·

Volume

Articles per year
162LetPub ·

Articles by year OpenAlex count · 5,123 in total · the current year is incomplete

YearArticlesOpen accessCitations
2026160114137
20251931431,641
20241691302,588
20231951355,427
20221661204,836
2021140915,332

Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.

Review & acceptance

Review time and acceptance

Review time from article dates manuscript dates registered with PubMed · to

90 daysMedian, submission to acceptance · P25–P75 63 days – 123 days

Acceptance to online
median 26 days (108 articles)
Submission to online
median 113 days
Sample
108 articles with submission and acceptance dates (365 in the window); the latest was accepted on

Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".

Other sources

Average review time (community reports)
6–12 weeksLetPub ·
Average acceptance (community reports)
Fairly hardLetPub ·
Submission to first decision
8 daysPublisher website ·
First decision after review
50 daysPublisher website ·
Submission to acceptance
91 daysPublisher website ·
Acceptance to publication
26 daysPublisher website ·
Peer review
Single anonymous peer reviewPublisher website

Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.

Fees & open access

APC and open-access policy

Hybrid open accessLetPub

A subscription journal in which authors can pay to publish their article open access.

SourceAPCFee waiverLicenseObserved
OpenAlexUSD 4,360 / EUR 4,080 / GBP 3,490 / JPY 540,770——
Publisher websiteUSD 4,170——

A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.

The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.

Submission

Article types and submission policies (journal website)

What to prepare5 items from the author guidelines
Abstract
≤ 120 words
Keywords
≥ 1
Reference style
Numbered, in order of citation
Highlights
Optional
Graphical abstract
Optional
Publisher website · model-extracted, each line checked against the text
Article types accepted4, with length limits
  1. opinione into account when preparing a Current Opinion paper: 2000 word limit (excluding abstract, references and figure captions)main text ≤ 2,000 words
  2. reviewtrate unduly on your own research. Your review should be approximately 2000 words (not including references or reference notes), with approximain text ≤ 2,000 words
  3. review articleThe Current Opinion journals were developed out of the recognition that it is increasingly difficult for specialists to keep up to date with the expanding volum…main text ≤ 2,000 words · references ≤ 50
  4. review articlesReview articles in COSB are by invitation only. The journal does not accept manuscripts other from those invited by guest editors, appointed by Editors-in-Chief…Length not stated
Publisher website
Policy excerpts from the journal's websiteAI use, Authorship, Conflicts of interest, License & copyright, Open access, Peer review, Preprints
AI use Declaration of generative AI use

Authors must declare the use of generative AI tools in the manuscript preparation process upon submission of the paper.Generative AI and AI-assisted technologies (“AI tools”) have been rapidly adopted in research and scholarly publishing, offering significant benefits while requiring clear standards for responsible and transparent use.Authors preparing a manuscript for this journal may use AI tool…

Source ↗Publisher website ·
Authorship Group authorship

Group authorship refers to the attribution of an article to a defined and named group of authors whose members have contributed to the work. Examples include research consortia, clinical trial groups, collaborative networks, task forces or working groups, expert panels or consensus groups, and participatory research groups. Group authorship must be declared on the title page at submission. When av…

Source ↗Publisher website ·
Conflicts of interest Declaration of competing interests

All authors must disclose any financial and personal relationships with other people or organizations that could inappropriately influence or bias their work. Examples of potential competing interests include:EmploymentConsultanciesStock ownershipHonorariaPaid expert testimonyPatent applications or registrationsGrants or any other fundingAffiliation with the journal as an Editor or Advisory Board …

Source ↗Publisher website ·
License & copyright License options

Authors will be offered open access user license options which will determine how you, and third parties, can reuse your open access article. We advise that you review these options and any funding body license requirements before selecting a license option.

Source ↗Publisher website ·
Open access Open access

Submission by invitation only. Model summary

We refer you to our open access information page to learn about open access options for this journal.

Source ↗Publisher website ·
Peer review Peer review

This journal follows a single anonymized review process. Your submission will initially be assessed by our editors. If your submission is deemed suitable, it will typically be sent to be reviewed by a minimum of one reviewer for an independent expert assessment of the scientific quality. The decision as to whether your article is accepted or rejected for publication will be made by our editors.Rea…

Source ↗Publisher website ·
Preprints Preprints

Preprint sharingAuthors may share preprints in line with Elsevier's article sharing policy. Sharing preprints, such as on a preprint server, will not count as prior publication.We advise you to read our policy on multiple, redundant or concurrent publication.

Source ↗Publisher website ·

Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.

Profile

Publication details and official links

Publisher
Elsevier Ltd
Country or region
ENGLAND
Language
English
Frequency
Bimonthly
Founded
1991
ISSN
0959-440X
Electronic ISSN
1879-033X
Official links

FAQ

Frequently asked questions about Current Opinion in Structural Biology

What CAS zone is Current Opinion in Structural Biology in?

In the 2025 upgraded edition of the CAS Journal Ranking, Current Opinion in Structural Biology is in Zone 2 of Biology, and in Zone 2 of the minor category Biochemistry & Molecular Biology / Cell Biology; it is a Top journal. In the 2026 Xinrui edition it is in Zone 2 of Biology. Zones from different editions, and from major and minor categories, are not interchangeable.

What is the impact factor of Current Opinion in Structural Biology?

The latest impact factor listed by LetPub is 7.69; CiteScore 13.7, h-index 255.

How long does peer review take at Current Opinion in Structural Biology?

Based on the dates recorded on 108 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 90 days (interquartile range 63–123 days); authors report an average review time of 6–12 weeks; the community-reported acceptance is “Fairly hard”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.

What are the manuscript requirements of Current Opinion in Structural Biology?

According to the journal's author guidelines: Abstract: ≤ 120 words; Keywords: ≥ 1; Reference style: Numbered, in order of citation; Highlights: Optional; Graphical abstract: Optional. A model extracted these from the author guidelines and each was checked against the text; check the latest version on the journal's website before submitting.

Where are the editorial board members of Current Opinion in Structural Biology based?

Of the 49 board members whose country the journal's board page names, 3 (about 6%) are in mainland China; the countries named most often are United Kingdom (13), United States (12) and Germany (5). Counted from the institutions listed on the board page; for reference only.

Which databases index Current Opinion in Structural Biology?

According to LetPub and DOAJ records, Current Opinion in Structural Biology is indexed in SCIE and Scopus.

Is Current Opinion in Structural Biology open access, and what is the APC?

Current Opinion in Structural Biology is a hybrid journal. For open-access publication: APC about USD 4,360.

Sources and updates

The facts on this page come from LetPub, Publisher website, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-26). Last updated: .