Journal profile · Medical Laboratory Technology

CLINICAL CHEMISTRY AND LABORATORY MEDICINE

ISSN 1434-6621 · eISSN 1437-4331 · Walter de Gruyter GmbH · GERMANY · Monthly · Founded 1998

CLINICAL CHEMISTRY AND LABORATORY MEDICINE: CAS Zone 2 · Medicine (2025 upgraded edition); impact factor 4.39; hybrid open access; APC about USD 2,712; median 48 days to acceptance (139 articles, last 24 months); community-reported acceptance: about 62.5%; 453 articles in 2025; indexed in SCIE and Scopus.

Impact factor4.39Latest value listed by LetPub
CAS zoneZone 2 · Medicine2025 upgraded edition, major category · 2026 Xinrui edition Zone 3 · Medicine
Review time48 daysMedian, submission to acceptance · 139 articles, last 24 months · PubMed
APCUSD 2,712Hybrid journal: charged only for open-access articles
Acceptanceabout 62.5%Community average
Articles per year4532025 · OpenAlex count

Scope

Aims, scope and focus

CLINICAL CHEMISTRY AND LABORATORY MEDICINE is published by Walter de Gruyter GmbH and is in Zone 2 of Medicine in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Clinical Laboratory Practices and Quality Control, Metabolism and Genetic Disorders and Folate and B Vitamins Research, together about 32.6% of its articles. (generated from OpenAlex topic counts and CAS ranking data)

About this journal ObjectiveClinical Chemistry and Laboratory Medicine (CCLM) publishes articles on novel teaching and training methods applicable to laboratory medicine. It is focused on basic and applied research and cutting-edge clinical laboratory medicine. CCLM is one of the leading international journals in the field of clinical laboratory sciences and drives progress in the field. CCLM is led by a multi-institutional editorial board. CCLM is a hybrid journal published monthly in print and online. All contributions submitted for publication in JPEM are subject to single-anonymized peer review by at least two experts in the field, selected and invited by the Editor-in-Chief and a dedicated Editorial Team. CCLM publishes only English-language articles.Letters to the Editor and Congress Abstracts are published online only.CCLM is the official journal of the European Federation of Cli nical Chemistry and Laboratory Medicine (EFLM).TopicsClinical Biochemistry // Clinical Genomics and Molecular Biology // Clinical Hematology and Hemostasis // Clinical Immunology and Autoimmunity // Clinical Microbiology // Drug Monitoring and Analysis // Evaluation of Diagnostic Biomarkers // Disease-Oriented Topics (Cardiovascular Disease, Cancer Diagnostics, Diabetes) // Clinical Evaluation of New Reagents, Instrumentation and Technologies // Innovative and/or Disruptive Analytical Techniques // Reference Materials and Methods // Reference Values and Decision Limits // Candidate Reference Measurement Procedures and Materials // Quality and Safety in Laboratory Medicine // Laboratory-Related Errors and Patient Safety // Standardization/Harmonization of Laboratory Assays // Translational Laboratory Medicine // Clinical MetrologyArticle formatsResearch Articles, Reviews, Mini Reviews, Opinion Papers Point/Counterpoint Articles, Perspectives, Gu idelines and Recommendations, Letters to the Editor, EditorialsUseful linksInstructions for Authors Submission ChecklistTemplate for Ethical and Legal DeclarationsManuscript Preparation and Manuscript TemplatesEuropean Federation of Clinical Chemistry and Laboratory Medicine (EFLM) EFLM Congress Calendar Resources for Authors License to Publish Author Language Service Data Sharing Policy Rights and Permissions Open Access 2025 Reviewer AcknowledgmentsFor EFLM Academy Members To take advantage of all the opportunities offered to members of the EFLM Academy, please access y our personal area in the EFLM Academy at the link https://acad

From the journal's Aims & Scope

Research area (LetPub): Medical Laboratory Technology

Editor-in-chief Mario PlebaniPublisher website

Main research topics OpenAlex counts of recent articles; shares are approximate

  1. Clinical Laboratory Practices and Quality ControlMedicine22.3%
  2. Metabolism and Genetic DisordersBiochemistry, Genetics and Molecular Biology5.7%
  3. Folate and B Vitamins ResearchMedicine4.6%
  4. Diabetes, Cardiovascular Risks, and LipoproteinsMedicine4.4%
  5. Meta-analysis and systematic reviewsDecision Sciences4.2%
  6. Sepsis Diagnosis and TreatmentMedicine3.7%
  7. Renal function and acid-base balanceMedicine3.7%
  8. Diverse Scientific and Economic StudiesEconomics, Econometrics and Finance3.6%

Rankings & indexing

CAS ranking and database indexing

CAS Journal Ranking

CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 2
LevelCategoryZone
MajorMedicineZone 2
MinorMedical Laboratory TechnologyZone 2

Top journal: noReview journal: no

CAS Xinrui Journal Ranking (March 2026)Medicine Zone 3
LevelCategoryZone
MajorMedicineZone 3
MinorMedical Laboratory TechnologyZone 2

Top journal: noReview journal: not marked

CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 2
LevelCategoryZone
MajorMedicineZone 2
MinorMedical Laboratory TechnologyZone 2

Top journal: noReview journal: no

Database indexing

SCIEScopusLetPub

International journal early-warning lists: not listed in any editionLetPub

Indexing the journal's website claims

CASCurrent ContentsPublisher website

Other: EBSCO, ProQuest, OCLC

As the journal's website lists them, not checked against each database; for Web of Science editions the records above apply.

Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.

Metrics

Impact metrics and publication volume

Impact

Impact factor
4.39LetPub ·
Impact factor (publisher)
4.4Publisher website ·
5-year impact factor (publisher)
4Publisher website ·
CiteScore 2026-06
7LetPub ·
CiteScore (publisher)
7Publisher website ·
SJR 2026-06
1.29LetPub ·
SNIP 2026-06
1.57LetPub ·
h-index
91LetPub ·
h-index
151OpenAlex ·
i10-index
5,584OpenAlex ·
2-year mean citedness
3.25OpenAlex ·
Self-citation rate
18.2%LetPub ·
Share of gold OA articles
32.49%LetPub ·

Volume

Articles per year
259LetPub ·

Articles by year OpenAlex count · 14,862 in total · the current year is incomplete

YearArticlesOpen accessCitations
2026340114192
20254531341,066
20243361532,410
20234583084,042
20223662254,625
20213382104,365

Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.

Review & acceptance

Review time and acceptance

Review time from article dates manuscript dates registered with PubMed · to

48 daysMedian, submission to acceptance · P25–P75 27 days – 86 days

Acceptance to online
median 17 days (139 articles)
Submission to online
median 71 days
Sample
139 articles with submission and acceptance dates (901 in the window); the latest was accepted on

Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".

Other sources

Average review time (community reports)
about 1 monthLetPub ·
Average acceptance (community reports)
62.5%LetPub ·
Peer review
Single anonymous peer reviewPublisher website

Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.

Fees & open access

APC and open-access policy

Hybrid open accessLetPub

A subscription journal in which authors can pay to publish their article open access.

SourceAPCFee waiverLicenseObserved
OpenAlexEUR 2,400——

A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.

The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.

Profile

Publication details and official links

Publisher
Walter de Gruyter GmbH
Country or region
GERMANY
Language
English
Frequency
Monthly
Founded
1998
ISSN
1434-6621
Electronic ISSN
1437-4331
Society / sponsor
European Federation of Clinical Chemistry and Laboratory Medicine
Official links

FAQ

Frequently asked questions about CLINICAL CHEMISTRY AND LABORATORY MEDICINE

What CAS zone is CLINICAL CHEMISTRY AND LABORATORY MEDICINE in?

In the 2025 upgraded edition of the CAS Journal Ranking, CLINICAL CHEMISTRY AND LABORATORY MEDICINE is in Zone 2 of Medicine, and in Zone 2 of the minor category Medical Laboratory Technology. In the 2026 Xinrui edition it is in Zone 3 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.

What is the impact factor of CLINICAL CHEMISTRY AND LABORATORY MEDICINE?

The latest impact factor listed by LetPub is 4.39; CiteScore 7, h-index 151.

How long does peer review take at CLINICAL CHEMISTRY AND LABORATORY MEDICINE?

Based on the dates recorded on 139 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 48 days (interquartile range 27–86 days); authors report an average review time of about 1 month; the community-reported acceptance is “about 62.5%”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.

Which databases index CLINICAL CHEMISTRY AND LABORATORY MEDICINE?

According to LetPub and DOAJ records, CLINICAL CHEMISTRY AND LABORATORY MEDICINE is indexed in SCIE and Scopus. The journal's website also lists CAS and Current Contents; that list has not been checked against each database.

Is CLINICAL CHEMISTRY AND LABORATORY MEDICINE open access, and what is the APC?

CLINICAL CHEMISTRY AND LABORATORY MEDICINE is a hybrid journal. For open-access publication: APC about USD 2,712.

Sources and updates

The facts on this page come from LetPub, OpenAlex, Publisher website; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .