Journal profile · Medical Laboratory Technology

Clinical Chemistry

ISSN 0009-9147 · eISSN 1530-8561 · American Association for Clinical Chemistry Inc. · UNITED STATES · Monthly · Founded 1955

Clinical Chemistry: CAS Zone 2 · Medicine (2025 upgraded edition); impact factor 7.85; hybrid open access; APC about USD 4,636; median 81 days to acceptance (97 articles, last 24 months); community-reported acceptance: fairly hard; 899 articles in 2025; indexed in SCIE and Scopus.

Impact factor7.85Latest value listed by LetPub
CAS zoneZone 2 · Medicine2025 upgraded edition, major category · 2026 Xinrui edition Zone 2 · Medicine
Review time81 daysMedian, submission to acceptance · 97 articles, last 24 months · PubMed
APCUSD 4,636Hybrid journal: charged only for open-access articles
AcceptanceFairly hardCommunity average
Articles per year8992025 · OpenAlex count

Scope

Aims, scope and focus

Clinical Chemistry is published by American Association for Clinical Chemistry Inc. and is in Zone 2 of Medicine in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Metabolism and Genetic Disorders, Clinical Laboratory Practices and Quality Control and Metabolomics and Mass Spectrometry Studies, together about 26.7% of its articles. (generated from OpenAlex topic counts and CAS ranking data)

Clinical Chemistry is a high-impact peer-reviewed publication, ranked as the most cited journal in the fields of clinical chemistry, clinical or anatomic

From the journal's Aims & Scope

Research area (LetPub): Medical Laboratory Technology

Editor-in-chief Jason Y. ParkPublisher website

Main research topics OpenAlex counts of recent articles; shares are approximate

  1. Metabolism and Genetic DisordersBiochemistry, Genetics and Molecular Biology10.5%
  2. Clinical Laboratory Practices and Quality ControlMedicine10.2%
  3. Metabolomics and Mass Spectrometry StudiesBiochemistry, Genetics and Molecular Biology6%
  4. Renal function and acid-base balanceMedicine5.5%
  5. Analytical Chemistry and ChromatographyChemistry4.4%
  6. Neonatal Health and BiochemistryMedicine4.4%
  7. Diabetes, Cardiovascular Risks, and LipoproteinsMedicine4.3%
  8. Monoclonal and Polyclonal Antibodies ResearchMedicine4.2%

Rankings & indexing

CAS ranking and database indexing

CAS Journal Ranking

CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 2
LevelCategoryZone
MajorMedicineZone 2
MinorMedical Laboratory TechnologyZone 1

Top journal: noReview journal: no

CAS Xinrui Journal Ranking (March 2026)Medicine Zone 2
LevelCategoryZone
MajorMedicineZone 2
MinorMedical Laboratory TechnologyZone 1

Top journal: noReview journal: not marked

CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 2
LevelCategoryZone
MajorMedicineZone 2
MinorMedical Laboratory TechnologyZone 1

Top journal: noReview journal: no

Database indexing

SCIEScopusLetPub

International journal early-warning lists: not listed in any editionLetPub

Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.

Metrics

Impact metrics and publication volume

Impact

Impact factor
7.85LetPub ·
Impact factor (publisher) 2025
2Publisher website ·
CiteScore 2026-06
9.8LetPub ·
SJR 2026-06
1.72LetPub ·
SNIP 2026-06
1.64LetPub ·
h-index
201LetPub ·
h-index
326OpenAlex ·
i10-index
14,920OpenAlex ·
2-year mean citedness
1.29OpenAlex ·
Self-citation rate
2.4%LetPub ·
Share of gold OA articles
32.5%LetPub ·

Volume

Articles per year
84LetPub ·

Articles by year OpenAlex count · 31,027 in total · the current year is incomplete

YearArticlesOpen accessCitations
20261013841
2025899708837
20248634681,518
20238407862,970
20222031832,551
20212821984,768

Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.

Review & acceptance

Review time and acceptance

Review time from article dates manuscript dates registered with PubMed · to

81 daysMedian, submission to acceptance · P25–P75 30 days – 118 days

Acceptance to online
median 42 days (32 articles)
Submission to online
median 145 days
Sample
97 articles with submission and acceptance dates (405 in the window); the latest was accepted on

Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".

Other sources

Average review time (community reports)
about 2 monthsLetPub ·
Average acceptance (community reports)
Fairly hardLetPub ·

Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.

Fees & open access

APC and open-access policy

Hybrid open accessLetPub

A subscription journal in which authors can pay to publish their article open access.

SourceAPCFee waiverLicenseObserved
OpenAlexUSD 4,636——

A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.

The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.

Submission

Article types and submission policies (journal website)

Policy excerpts from the journal's websiteOpen access
Open access Latest Open Access Article

Plasma Cell Leukemia with A “Missing” Monoclonal Protein on Immunofixation Jack L Wu and others Clinical Chemistry, Volume 72, Issue 9, September 2026, Pages 920–923, https://doi.org/10.1093/clinchem/hvag064 A 64-year-old male presented with weight loss, fatigue, and abdominal pain. Imaging demonstrated multifocal abdominal and retroperitoneal lymphadenopathy. Laboratory evaluation revealed signif…

Source ↗Publisher website ·

Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.

Profile

Publication details and official links

Publisher
American Association for Clinical Chemistry Inc.
Country or region
UNITED STATES
Language
English
Frequency
Monthly
Founded
1955
ISSN
0009-9147
Electronic ISSN
1530-8561
Latest issue on the website
Volume 72, Issue 9 (September 2026)
Official links

FAQ

Frequently asked questions about Clinical Chemistry

What CAS zone is Clinical Chemistry in?

In the 2025 upgraded edition of the CAS Journal Ranking, Clinical Chemistry is in Zone 2 of Medicine, and in Zone 1 of the minor category Medical Laboratory Technology. In the 2026 Xinrui edition it is in Zone 2 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.

What is the impact factor of Clinical Chemistry?

The latest impact factor listed by LetPub is 7.85; CiteScore 9.8, h-index 326.

How long does peer review take at Clinical Chemistry?

Based on the dates recorded on 97 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 81 days (interquartile range 30–118 days); authors report an average review time of about 2 months; the community-reported acceptance is “Fairly hard”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.

Which databases index Clinical Chemistry?

According to LetPub and DOAJ records, Clinical Chemistry is indexed in SCIE and Scopus.

Is Clinical Chemistry open access, and what is the APC?

Clinical Chemistry is a hybrid journal. For open-access publication: APC about USD 4,636.

Sources and updates

The facts on this page come from LetPub, OpenAlex, Publisher website; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .