Journal profile · Medicine, Research & Experimental
Clinical and Experimental Medicine
ISSN 1591-8890 · eISSN 1591-9528 · Springer International Publishing · ITALY · Quarterly · Founded 2001
Clinical and Experimental Medicine: CAS Zone 4 · Medicine (2025 upgraded edition); impact factor 4.5; hybrid open access; APC about USD 4,790; median 65 days to acceptance (111 articles, last 24 months); community-reported acceptance: about 77.5%; 437 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
Clinical and Experimental Medicine is published by Springer International Publishing and is in Zone 4 of Medicine in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Biomedical and Chemical Research, Ferroptosis and cancer prognosis and Immune Cell Function and Interaction, together about 24.5% of its articles. (generated from OpenAlex topic counts and CAS ranking data)
Clinical and Experimental Medicine (CLEM) is a multidisciplinary journal that aims to be a forum of scientific excellence and information exchange in relation to the basic and clinical features of the following fields: hematology, onco-hematology, oncology, virology, immunology, and rheumatology. The journal publishes reviews and editorials, experimental and preclinical studies, translational research, prospectively designed clinical trials, and epidemiological studies. Papers containing new clinical or experimental data that are likely to contribute to changes in clinical practice or the way in which a disease is thought about will be given priority due to their immediate importance. Case reports will be accepted on an exceptional basis only, and their submission is discouraged. The major criteria for publication are clarity, scientific soundness, and advances in knowledge. Following submission via the Springer Nature Article Processing Platform (SNAPP), articles are peer-reviewed (under single blind peer review process) and, if accepted, are rapidly published, resulting in immediate international exposure through PubMed/MEDLINE indexing. This journal also publishes special/guest-edited issues. The peer review process for these articles is the same as the peer review process of the journal in general. Additionally, if the guest editor(s) authors an article in their special issue, they will not handle the peer review process.
From the journal's Aims & Scope
Research area (LetPub): Medicine, Research & Experimental
Editor-in-chief Franco DammaccoPublisher website
Editorial board by country: 2 in mainland China (about 4%); most named Italy 20, United States 12, United Kingdom 4, Japan 3, Mainland China 2 (56 members with a country) Editorial board ↗Publisher website ·
Main research topics OpenAlex counts of recent articles; shares are approximate
- Biomedical and Chemical ResearchMedicine12.9%
- Ferroptosis and cancer prognosisMedicine6.1%
- Immune Cell Function and InteractionImmunology and Microbiology5.6%
- Cancer Immunotherapy and BiomarkersMedicine5.4%
- Liver Disease Diagnosis and TreatmentMedicine5.2%
- Systemic Lupus Erythematosus ResearchMedicine4.7%
- Cancer-related molecular mechanisms researchBiochemistry, Genetics and Molecular Biology4.6%
- Metabolism and Genetic DisordersBiochemistry, Genetics and Molecular Biology4.4%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 4 |
| Minor | Medicine, Research & Experimental | Zone 4 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Medicine Zone 3
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 3 |
| Minor | Medicine, Research & Experimental | Zone 3 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 4 |
| Minor | Medicine, Research & Experimental | Zone 4 |
Top journal: noReview journal: no
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Indexing the journal's website claims
MEDLINEEmbaseCASCAB AbstractsPublisher website
Other: Google Scholar, EBSCO, ProQuest, Dimensions, CNKI, Baidu, Naver, OCLC, Portico, CLOCKSS, Semantic Scholar
As the journal's website lists them, not checked against each database; for Web of Science editions the records above apply.
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 4.5LetPub ·
- Impact factor (publisher) 2025
- 4.5Publisher website ·
- 5-year impact factor (publisher) 2025
- 4.4Publisher website ·
- CiteScore 2026-06
- 6.7LetPub ·
- SJR 2026-06
- 1.18LetPub ·
- SNIP 2026-06
- 1.14LetPub ·
- h-index
- 39LetPub ·
- h-index
- 76OpenAlex ·
- i10-index
- 1,461OpenAlex ·
- 2-year mean citedness
- 5.47OpenAlex ·
- Self-citation rate
- 0%LetPub ·
- Share of gold OA articles
- 80.45%LetPub ·
Volume
- Articles per year
- 419LetPub ·
- Downloads per year (publisher) 2025
- 1,400,000Publisher website ·
Articles by year OpenAlex count · 4,473 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 315 | 315 | 183 |
| 2025 | 437 | 437 | 2,302 |
| 2024 | 276 | 276 | 3,143 |
| 2023 | 275 | 112 | 2,977 |
| 2022 | 198 | 86 | 3,257 |
| 2021 | 102 | 41 | 2,424 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with Crossref · to
65 daysMedian, submission to acceptance · P25–P75 47 days – 107 days
- Acceptance to online
- median 24 days (111 articles)
- Submission to online
- median 109 days
- Sample
- 111 articles with submission and acceptance dates (798 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Average review time (community reports)
- about 2.5 monthsLetPub ·
- Average acceptance (community reports)
- 77.5%LetPub ·
- Submission to first decision
- 3 daysPublisher website ·
- Peer review
- Double anonymous peer reviewPublisher website
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Hybrid open accessLetPub
A subscription journal in which authors can pay to publish their article open access.
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| OpenAlex | USD 4,790 / EUR 3,590 / GBP 2,990 | — | — |
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
Other charges and waivers (author guidelines)
- Other fees
- No other fees
- Page charges
- Charged; see the journal's website for the amount
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
Open calls for papers3, by deadline
Publisher websiteWhat to prepare5 items from the author guidelines
- Abstract
- 150–250 words
- Keywords
- ≥ 4
- Manuscript length
- ≤ 3,000 words
- Reference style
- Numbered, in order of citation
- Suggested reviewers
- Optional
Article types accepted6, with length limits
- correspondenceThe journal Clinical and Experimental Medicine publishes reports of clinical and experimental work concerned with the following fields: clinical chemistry, hema…Length not stated
- original articleThe journal Clinical and Experimental Medicine publishes reports of clinical and experimental work concerned with the following fields: clinical chemistry, hema…Length not stated
- original paperThe journal Clinical and Experimental Medicine publishes reports of clinical and experimental work concerned with the following fields: clinical chemistry, hema…Length not stated
- research articleThe journal Clinical and Experimental Medicine publishes reports of clinical and experimental work concerned with the following fields: clinical chemistry, hema…main text ≤ 3,000 words
- reviewThe journal Clinical and Experimental Medicine publishes reports of clinical and experimental work concerned with the following fields: clinical chemistry, hema…Length not stated
- review articleThe journal Clinical and Experimental Medicine publishes reports of clinical and experimental work concerned with the following fields: clinical chemistry, hema…main text ≤ 5,000 words · figures and tables ≤ 6 · references ≤ 80
Policy excerpts from the journal's websiteAI use, Authorship, Conflicts of interest, Data availability, Publication ethics, License & copyright, Open access, Peer review, Trial registration / reporting guidelines
- AI use Generative AI Images
LLMs do not satisfy authorship criteria; LLM use must be documented in Methods; AI-assisted copy editing need not be declared. Model summary
Please check Springer’s policy on generative AI images and make sure your work adheres to the principles described therein. Back to top
Source ↗Publisher website ·- Authorship Authorship principles
These guidelines describe authorship principles and good authorship practices to which prospective authors should adhere to. Authorship clarified The Journal and Publisher assume all authors agreed with the content and that all gave explicit consent to submit and that they obtained consent from the responsible authorities at the institute/organization where the work has been carried out, before th…
Source ↗Publisher website ·- Conflicts of interest Disclosures and declarations
All authors are requested to include information regarding sources of funding, financial or non-financial interests, study-specific approval by the appropriate ethics committee for research involving humans and/or animals, informed consent if the research involved human participants, and a statement on welfare of animals if the research involved animals (as appropriate). The decision whether such …
Source ↗Publisher website ·- Data availability Data availability statements
Data transparency: all data, materials, software or custom code supporting published claims; individual data sharing policies. Model summary
All original research must include a data availability statement. This statement should explain how to access data supporting the results and analysis in the article, including links/citations to publicly archived datasets analysed or generated during the study. Please see our full policy here. If it is not possible to share research data publicly, for instance when individual privacy could be com…
Source ↗Publisher website ·- Publication ethics Compliance with Ethical Standards
COPE member; follows COPE guidelines on misconduct. Model summary
To ensure objectivity and transparency in research and to ensure that accepted principles of ethical and professional conduct have been followed, authors should include information regarding sources of funding, potential conflicts of interest (financial or non-financial), informed consent if the research involved human participants, and a statement on welfare of animals if the research involved an…
Source ↗Publisher website ·- License & copyright Copyright
Articles in Springer Nature open access journals do not require transfer of copyright as the copyright remains with the author. Details of the OA licences offered to authors can be found on the individual journal website, in the journal's How to publish with us guide. Back to top
Source ↗Publisher website ·- Open access Open access publishing
To find out more about publishing your work Open Access in Clinical and Experimental Medicine, including information on fees, funding and licences, visit our Open access publishing page. Back to top
Source ↗Publisher website ·- Peer review
Authors may suggest or exclude reviewers; suggested reviewers must be independent and provide institutional email or identity verification. Model summary
Authors are welcome to suggest suitable reviewers and/or request the exclusion of certain individuals when they submit their manuscripts.
Source ↗Publisher website ·- Trial registration / reporting guidelines Clinical Trial Registration
The World Health Organization (WHO) definition of a clinical trial is "any research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes". The WHO defines health interventions as “A health intervention is an act performed for, with or on behalf of a person or population whose purpose is to ass…
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- Springer International Publishing
- Country or region
- ITALY
- Language
- English
- Frequency
- Quarterly
- Founded
- 2001
- ISSN
- 1591-8890
- Electronic ISSN
- 1591-9528
- Official links
- Journal homepage ↗OpenAlex
- Submission system ↗Publisher website
- Author guidelines ↗LetPub
- Special issues ↗Publisher website
FAQ
Frequently asked questions about Clinical and Experimental Medicine
What CAS zone is Clinical and Experimental Medicine in?
In the 2025 upgraded edition of the CAS Journal Ranking, Clinical and Experimental Medicine is in Zone 4 of Medicine, and in Zone 4 of the minor category Medicine, Research & Experimental. In the 2026 Xinrui edition it is in Zone 3 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Clinical and Experimental Medicine?
The latest impact factor listed by LetPub is 4.5; CiteScore 6.7, h-index 76.
How long does peer review take at Clinical and Experimental Medicine?
Based on the dates recorded on 111 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 65 days (interquartile range 47–107 days); authors report an average review time of about 2.5 months; the community-reported acceptance is “about 77.5%”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
What are the manuscript requirements of Clinical and Experimental Medicine?
According to the journal's author guidelines: Abstract: 150–250 words; Keywords: ≥ 4; Manuscript length: ≤ 3,000 words; Reference style: Numbered, in order of citation; Suggested reviewers: Optional. A model extracted these from the author guidelines and each was checked against the text; check the latest version on the journal's website before submitting.
Where are the editorial board members of Clinical and Experimental Medicine based?
Of the 56 board members whose country the journal's board page names, 2 (about 4%) are in mainland China; the countries named most often are Italy (20), United States (12) and United Kingdom (4). Counted from the institutions listed on the board page; for reference only.
Which databases index Clinical and Experimental Medicine?
According to LetPub and DOAJ records, Clinical and Experimental Medicine is indexed in SCIE and Scopus. The journal's website also lists MEDLINE, Embase, CAS and CAB Abstracts; that list has not been checked against each database.
Is Clinical and Experimental Medicine open access, and what is the APC?
Clinical and Experimental Medicine is a hybrid journal. For open-access publication: APC about USD 4,790.
Sources and updates
The facts on this page come from LetPub, OpenAlex, Publisher website; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-26). Last updated: .