Journal profile · Medicine-Pathology and Forensic Medicine

Cell Systems

ISSN 2405-4712 · eISSN 2405-4720 · Cell Press · UNITED STATES

Cell Systems: CAS Zone 1 · Biology (2025 upgraded edition, Top journal); impact factor 7.56; hybrid open access; APC about USD 9,350; median 358 days to acceptance (97 articles, last 24 months); 132 articles in 2025; indexed in SCIE and Scopus.

Impact factor7.56Latest value listed by LetPub
CAS zoneZone 1 · Biology2025 upgraded edition, major category · Top journal · 2026 Xinrui edition Zone 1 · Biology
Review time358 daysMedian, submission to acceptance · 97 articles, last 24 months · PubMed
APCUSD 9,350Hybrid journal: charged only for open-access articles
Acceptance—No reports yet
Articles per year1322025 · OpenAlex count

Scope

Aims, scope and focus

Cell Systems is published by Cell Press and is in Zone 1 of Biology in the CAS Journal Ranking (2025 upgraded edition, Top journal). By OpenAlex counts of its recent articles, its largest topics are Gene Regulatory Network Analysis, Single-cell and spatial transcriptomics and Bioinformatics and Genomic Networks, together about 30.7% of its articles. Its main subfields are Molecular Biology. (generated from OpenAlex topic counts and CAS ranking data)

Cell Systems was established in 2015 to provide a home at Cell Press for elegant work that addresses fundamental questions in systems biology. "Systems biology," as we broadly define it, is work that develops a rigorous understanding of any biological phenomenon where one plus one does not apparently equal two. Disciplines in the physical sciences have met this challenge for a long time, and we've found that our strongest papers tend to apply quantitative, inference-based approaches taken in physics, engineering, mathematics, and computer science to salient biological questions.We believe it's our responsibility to ensure that the next generation of scientists can begin their work on solid ground. Accordingly, we focus our review process on validity and scientific acuity, rather than more subjective feelings and opinions. We also believe that scientific transparency is of paramount importance. A study's structure and presentation should be candid and forthright (e.g. it should ensure fair comparisons; it should either use non-arbitrary cut-offs or clearly explained arbitrary cut-offs that do not affect outcomes; its data visualization choices should promote objective understanding; its limitations should not be obscured). Fundamentally good scientific practice also demands that studies be repeatable. We encourage authors to make their code and data FAIR, that is findable, accessible, interoperable, and reusable, as defined by the NIH data commons. Although it is too early to formally require that all studies we publish be FAIR, we consider that requirement annually.As editors, we hold ourselves to the same standards of transparency but also recognize that living up to those standards requires constant effort. Like all journals, Cell Systems is a work in progress. A collection of editorials that document our thoughts and their evolution can be found here. We are always happy to talk to you.

From the journal's Aims & Scope

Research area (LetPub): Medicine-Pathology and Forensic Medicine

Main research topics OpenAlex counts of recent articles; shares are approximate

  1. Gene Regulatory Network AnalysisBiochemistry, Genetics and Molecular Biology12.3%
  2. Single-cell and spatial transcriptomicsBiochemistry, Genetics and Molecular Biology11%
  3. Bioinformatics and Genomic NetworksBiochemistry, Genetics and Molecular Biology7.4%
  4. RNA and protein synthesis mechanismsBiochemistry, Genetics and Molecular Biology6.8%
  5. Cell Image Analysis TechniquesBiochemistry, Genetics and Molecular Biology6.2%
  6. CRISPR and Genetic EngineeringBiochemistry, Genetics and Molecular Biology5.6%
  7. Genomics and Chromatin DynamicsBiochemistry, Genetics and Molecular Biology4.8%
  8. Microbial Metabolic Engineering and BioproductionBiochemistry, Genetics and Molecular Biology4.4%

Rankings & indexing

CAS ranking and database indexing

CAS Journal Ranking

CAS Journal Ranking, upgraded edition (March 2025)Biology Zone 1
LevelCategoryZone
MajorBiologyZone 1
MinorBiochemistry & Molecular BiologyZone 1
MinorCell BiologyZone 2

Top journal: yesReview journal: no

CAS Xinrui Journal Ranking (March 2026)Biology Zone 1
LevelCategoryZone
MajorBiologyZone 1
MinorBiochemistry & Molecular BiologyZone 1
MinorCell BiologyZone 2

Top journal: yesReview journal: not marked

CAS Journal Ranking, previous upgraded edition (December 2023)Biology Zone 1
LevelCategoryZone
MajorBiologyZone 1
MinorBiochemistry & Molecular BiologyZone 1
MinorCell BiologyZone 2

Top journal: yesReview journal: no

Database indexing

SCIEScopusLetPub

International journal early-warning lists: not listed in any editionLetPub

Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.

Metrics

Impact metrics and publication volume

Impact

Impact factor
7.56LetPub ·
Impact factor (publisher)
7.5Publisher website ·
CiteScore 2026-06
11.5LetPub ·
CiteScore (publisher)
11.5Publisher website ·
SJR 2026-06
4.95LetPub ·
SNIP 2026-06
1.69LetPub ·
h-index
30LetPub ·
h-index
142OpenAlex ·
i10-index
847OpenAlex ·
2-year mean citedness
6.35OpenAlex ·
Self-citation rate
2.7%LetPub ·
Share of gold OA articles
32.06%LetPub ·

Volume

Articles per year
106LetPub ·

Articles by year OpenAlex count · 1,419 in total · the current year is incomplete

YearArticlesOpen accessCitations
202612276165
202513288743
20241091091,396
202397973,160
202279792,443
20211091096,633

Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.

Review & acceptance

Review time and acceptance

Review time from article dates manuscript dates registered with PubMed · to

358 daysMedian, submission to acceptance · P25–P75 280 days – 481 days

Acceptance to online
median 30 days (91 articles)
Submission to online
median 393 days
Sample
97 articles with submission and acceptance dates (296 in the window); the latest was accepted on

Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".

Other sources

Submission to first decision
11 daysPublisher website ·
First decision after review
83 daysPublisher website ·
Submission to acceptance
274 daysPublisher website ·
Acceptance to publication
27 daysPublisher website ·

Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.

Fees & open access

APC and open-access policy

Hybrid open accessLetPub

A subscription journal in which authors can pay to publish their article open access.

SourceAPCFee waiverLicenseObserved
OpenAlexUSD 9,350 / EUR 8,660 / GBP 7,490 / JPY 1,159,680——
Publisher websiteUSD 9,350——

A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.

The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.

Submission

Article types and submission policies (journal website)

Policy excerpts from the journal's websiteOpen access
Open access Open Access

Article Publishing Charge (APC): USD 9,350 (excluding taxes). The amount you pay may be reduced during submission if applicable.

Source ↗Publisher website ·

Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.

Profile

Publication details and official links

Publisher
Cell Press
Country or region
UNITED STATES
Language
English
ISSN
2405-4712
Electronic ISSN
2405-4720
Official links

FAQ

Frequently asked questions about Cell Systems

What CAS zone is Cell Systems in?

In the 2025 upgraded edition of the CAS Journal Ranking, Cell Systems is in Zone 1 of Biology, and in Zone 1 of the minor category Biochemistry & Molecular Biology / Cell Biology; it is a Top journal. In the 2026 Xinrui edition it is in Zone 1 of Biology. Zones from different editions, and from major and minor categories, are not interchangeable.

What is the impact factor of Cell Systems?

The latest impact factor listed by LetPub is 7.56; CiteScore 11.5, h-index 142.

How long does peer review take at Cell Systems?

Based on the dates recorded on 97 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 358 days (interquartile range 280–481 days). Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.

Which databases index Cell Systems?

According to LetPub and DOAJ records, Cell Systems is indexed in SCIE and Scopus.

Is Cell Systems open access, and what is the APC?

Cell Systems is a hybrid journal. For open-access publication: APC about USD 9,350.

Sources and updates

The facts on this page come from LetPub, Publisher website, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .