Journal profile · Medicine-Pathology and Forensic Medicine
Cell Systems
ISSN 2405-4712 · eISSN 2405-4720 · Cell Press · UNITED STATES
Cell Systems: CAS Zone 1 · Biology (2025 upgraded edition, Top journal); impact factor 7.56; hybrid open access; APC about USD 9,350; median 358 days to acceptance (97 articles, last 24 months); 132 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
Cell Systems is published by Cell Press and is in Zone 1 of Biology in the CAS Journal Ranking (2025 upgraded edition, Top journal). By OpenAlex counts of its recent articles, its largest topics are Gene Regulatory Network Analysis, Single-cell and spatial transcriptomics and Bioinformatics and Genomic Networks, together about 30.7% of its articles. Its main subfields are Molecular Biology. (generated from OpenAlex topic counts and CAS ranking data)
Cell Systems was established in 2015 to provide a home at Cell Press for elegant work that addresses fundamental questions in systems biology. "Systems biology," as we broadly define it, is work that develops a rigorous understanding of any biological phenomenon where one plus one does not apparently equal two. Disciplines in the physical sciences have met this challenge for a long time, and we've found that our strongest papers tend to apply quantitative, inference-based approaches taken in physics, engineering, mathematics, and computer science to salient biological questions.We believe it's our responsibility to ensure that the next generation of scientists can begin their work on solid ground. Accordingly, we focus our review process on validity and scientific acuity, rather than more subjective feelings and opinions. We also believe that scientific transparency is of paramount importance. A study's structure and presentation should be candid and forthright (e.g. it should ensure fair comparisons; it should either use non-arbitrary cut-offs or clearly explained arbitrary cut-offs that do not affect outcomes; its data visualization choices should promote objective understanding; its limitations should not be obscured). Fundamentally good scientific practice also demands that studies be repeatable. We encourage authors to make their code and data FAIR, that is findable, accessible, interoperable, and reusable, as defined by the NIH data commons. Although it is too early to formally require that all studies we publish be FAIR, we consider that requirement annually.As editors, we hold ourselves to the same standards of transparency but also recognize that living up to those standards requires constant effort. Like all journals, Cell Systems is a work in progress. A collection of editorials that document our thoughts and their evolution can be found here. We are always happy to talk to you.
From the journal's Aims & Scope
Research area (LetPub): Medicine-Pathology and Forensic Medicine
Main research topics OpenAlex counts of recent articles; shares are approximate
- Gene Regulatory Network AnalysisBiochemistry, Genetics and Molecular Biology12.3%
- Single-cell and spatial transcriptomicsBiochemistry, Genetics and Molecular Biology11%
- Bioinformatics and Genomic NetworksBiochemistry, Genetics and Molecular Biology7.4%
- RNA and protein synthesis mechanismsBiochemistry, Genetics and Molecular Biology6.8%
- Cell Image Analysis TechniquesBiochemistry, Genetics and Molecular Biology6.2%
- CRISPR and Genetic EngineeringBiochemistry, Genetics and Molecular Biology5.6%
- Genomics and Chromatin DynamicsBiochemistry, Genetics and Molecular Biology4.8%
- Microbial Metabolic Engineering and BioproductionBiochemistry, Genetics and Molecular Biology4.4%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Biology Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 1 |
| Minor | Biochemistry & Molecular Biology | Zone 1 |
| Minor | Cell Biology | Zone 2 |
Top journal: yesReview journal: no
CAS Xinrui Journal Ranking (March 2026)Biology Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 1 |
| Minor | Biochemistry & Molecular Biology | Zone 1 |
| Minor | Cell Biology | Zone 2 |
Top journal: yesReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Biology Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 1 |
| Minor | Biochemistry & Molecular Biology | Zone 1 |
| Minor | Cell Biology | Zone 2 |
Top journal: yesReview journal: no
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 7.56LetPub ·
- Impact factor (publisher)
- 7.5Publisher website ·
- CiteScore 2026-06
- 11.5LetPub ·
- CiteScore (publisher)
- 11.5Publisher website ·
- SJR 2026-06
- 4.95LetPub ·
- SNIP 2026-06
- 1.69LetPub ·
- h-index
- 30LetPub ·
- h-index
- 142OpenAlex ·
- i10-index
- 847OpenAlex ·
- 2-year mean citedness
- 6.35OpenAlex ·
- Self-citation rate
- 2.7%LetPub ·
- Share of gold OA articles
- 32.06%LetPub ·
Volume
- Articles per year
- 106LetPub ·
Articles by year OpenAlex count · 1,419 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 122 | 76 | 165 |
| 2025 | 132 | 88 | 743 |
| 2024 | 109 | 109 | 1,396 |
| 2023 | 97 | 97 | 3,160 |
| 2022 | 79 | 79 | 2,443 |
| 2021 | 109 | 109 | 6,633 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with PubMed · to
358 daysMedian, submission to acceptance · P25–P75 280 days – 481 days
- Acceptance to online
- median 30 days (91 articles)
- Submission to online
- median 393 days
- Sample
- 97 articles with submission and acceptance dates (296 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Submission to first decision
- 11 daysPublisher website ·
- First decision after review
- 83 daysPublisher website ·
- Submission to acceptance
- 274 daysPublisher website ·
- Acceptance to publication
- 27 daysPublisher website ·
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
A subscription journal in which authors can pay to publish their article open access.
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| OpenAlex | USD 9,350 / EUR 8,660 / GBP 7,490 / JPY 1,159,680 | — | — | |
| Publisher website | USD 9,350 | — | — |
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
Policy excerpts from the journal's websiteOpen access
- Open access Open Access
Article Publishing Charge (APC): USD 9,350 (excluding taxes). The amount you pay may be reduced during submission if applicable.
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- Cell Press
- Country or region
- UNITED STATES
- Language
- English
- ISSN
- 2405-4712
- Electronic ISSN
- 2405-4720
- Official links
- Journal homepage ↗OpenAlex
- Submission system ↗Publisher website
- Special issues ↗Publisher website
FAQ
Frequently asked questions about Cell Systems
What CAS zone is Cell Systems in?
In the 2025 upgraded edition of the CAS Journal Ranking, Cell Systems is in Zone 1 of Biology, and in Zone 1 of the minor category Biochemistry & Molecular Biology / Cell Biology; it is a Top journal. In the 2026 Xinrui edition it is in Zone 1 of Biology. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Cell Systems?
The latest impact factor listed by LetPub is 7.56; CiteScore 11.5, h-index 142.
How long does peer review take at Cell Systems?
Based on the dates recorded on 97 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 358 days (interquartile range 280–481 days). Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
Which databases index Cell Systems?
According to LetPub and DOAJ records, Cell Systems is indexed in SCIE and Scopus.
Is Cell Systems open access, and what is the APC?
Cell Systems is a hybrid journal. For open-access publication: APC about USD 9,350.
Sources and updates
The facts on this page come from LetPub, Publisher website, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .