Journal profile · Toxicology
Archives of Toxicology
ISSN 0340-5761 · eISSN 1432-0738 · Springer Berlin Heidelberg · GERMANY · Monthly · Founded 1930
Archives of Toxicology: CAS Zone 2 · Medicine (2025 upgraded edition); impact factor 11; hybrid open access; APC about USD 5,690; median 68 days to acceptance (116 articles, last 24 months); community-reported acceptance: about 25%; 323 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
Archives of Toxicology is published by Springer Berlin Heidelberg and is in Zone 2 of Medicine in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Carcinogens and Genotoxicity Assessment, Poisoning and overdose treatments and Effects and risks of endocrine disrupting chemicals, together about 29.3% of its articles. Its main subfields are Health, Toxicology and Mutagenesis. (generated from OpenAlex topic counts and CAS ranking data)
The Archives of Toxicology aim to promote our understanding of toxic as well as pathophysiological mechanisms relevant to the mode of action of chemicals on human and mammalian cells and organisms. Particularly welcome are Short Communications, Review Articles, Original Articles, and Commentaries that focus on: molecular mechanisms of toxic substances in vitro techniques for toxicity testing and regulatory toxicology advances in "omics" techniques for identification and classification of toxic substances mechanisms and relevance of metabolic activation and inactivation Additional information Modern toxicology faces several major challenges. Firstly, the available toxicological data are insufficient for a large number of chemicals to which humans are exposed. Because our testing capacities are not sufficient to evaluate each individual compound or even mixtures of compounds in a reasonable time, new, more efficient techniques and testing strategies are required. Secondly, toxicology must keep pace with the rapidly growing knowledge about the molecular mechanisms responsible for adverse health effects because without this knowledge, toxicological risk evaluation will remain incomplete. Therefore, articles examining toxic as well as pathophysiological mechanisms relevant to the mode of action of chemicals on the human and mammalian organism will continue to be a major focus of our journal. Thirdly, advances in "omics" technologies and systems biology approaches have provided fresh insight into the complex interrelationships among the large numbers of factors involved. Therefore in future, a major challenge will be to model biological systems and quantitatively simulate perturbations by toxic substances. Finally, unrealistic expectations by parts of our society, including some politicians, represent a major challenge to toxicol ogy. One particular example is the unrealistic expectation that animal experiments can be replaced by in vitro techniques within a few years, without increasing the risk of adverse consequences for human health. The opinion that virtually all toxicity testing can be conducted in human cell lines or primary cells and the required dose-response relationships can be achieved by pharmacokinetic models is an easy one to have. Unfortunately, being able to experimentally deliver such results is extremely challenging. Authors who have achieved specific progress in this important field of research are particularly encouraged to submit their resu
From the journal's Aims & Scope
Research area (LetPub): Toxicology
Editor-in-chief Jan G. HengstlerPublisher website
Editorial board by country: 5 in mainland China (about 12%); most named Germany 16, Mainland China 5, United States 3, Japan 3, Netherlands 2 (42 members with a country) Editorial board ↗Publisher website ·
Main research topics OpenAlex counts of recent articles; shares are approximate
- Carcinogens and Genotoxicity AssessmentBiochemistry, Genetics and Molecular Biology13.1%
- Poisoning and overdose treatmentsMedicine8.7%
- Effects and risks of endocrine disrupting chemicalsEnvironmental Science7.5%
- Pesticide Exposure and ToxicityAgricultural and Biological Sciences7.3%
- Pharmacogenetics and Drug MetabolismPharmacology, Toxicology and Pharmaceutics6.6%
- Heavy Metal Exposure and ToxicityEnvironmental Science6%
- Drug-Induced Hepatotoxicity and ProtectionPharmacology, Toxicology and Pharmaceutics5.8%
- Toxic Organic Pollutants ImpactEnvironmental Science5.2%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 2 |
| Minor | Toxicology | Zone 1 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Medicine Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 2 |
| Minor | Toxicology | Zone 1 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 2 |
| Minor | Toxicology | Zone 1 |
Top journal: noReview journal: no
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Indexing the journal's website claims
MEDLINEEmbaseCASCAB AbstractsCurrent ContentsPublisher website
Other: Google Scholar, EBSCO, ProQuest, Dimensions, CNKI, Baidu, AGRICOLA, Astrophysics Data System, Naver, OCLC, Portico, CLOCKSS
As the journal's website lists them, not checked against each database; for Web of Science editions the records above apply.
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 11LetPub ·
- Impact factor (publisher) 2025
- 10.9Publisher website ·
- 5-year impact factor (publisher) 2025
- 8.4Publisher website ·
- CiteScore 2026-06
- 12.7LetPub ·
- SJR 2026-06
- 1.92LetPub ·
- SNIP 2026-06
- 2.05LetPub ·
- h-index
- 96LetPub ·
- h-index
- 184OpenAlex ·
- i10-index
- 5,480OpenAlex ·
- 2-year mean citedness
- 9.06OpenAlex ·
- Self-citation rate
- 1.8%LetPub ·
- Share of gold OA articles
- 48.75%LetPub ·
Volume
- Articles per year
- 301LetPub ·
- Downloads per year (publisher) 2025
- 2,500,000Publisher website ·
Articles by year OpenAlex count · 9,687 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 299 | 179 | 227 |
| 2025 | 323 | 183 | 2,184 |
| 2024 | 281 | 155 | 5,768 |
| 2023 | 219 | 145 | 7,502 |
| 2022 | 234 | 134 | 5,886 |
| 2021 | 241 | 162 | 6,555 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with Crossref · to
68 daysMedian, submission to acceptance · P25–P75 47 days – 100 days
- Acceptance to online
- median 18 days (116 articles)
- Submission to online
- median 94 days
- Sample
- 116 articles with submission and acceptance dates (678 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Average review time (community reports)
- about 1.5 monthsLetPub ·
- Average acceptance (community reports)
- 25%LetPub ·
- Submission to first decision
- 10 daysPublisher website ·
- Peer review
- Double anonymous peer reviewPublisher website
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Hybrid open accessLetPub
A subscription journal in which authors can pay to publish their article open access.
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| OpenAlex | USD 5,690 / EUR 4,390 / GBP 3,790 | — | — |
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
What to prepare4 items from the author guidelines
- Abstract
- 150–250 words
- Keywords
- ≥ 4
- Suggested reviewers
- Optional
- Cover letter
- Required
Article types accepted5, with length limits
- commentaryShort reports - Short reports on results that are of special interest for the community will be published directly as a Short Communications article and given p…Length not stated
- editorialShort reports - Short reports on results that are of special interest for the community will be published directly as a Short Communications article and given p…Length not stated
- letterShort reports - Short reports on results that are of special interest for the community will be published directly as a Short Communications article and given p…Length not stated
- opinionShort reports - Short reports on results that are of special interest for the community will be published directly as a Short Communications article and given p…Length not stated
- short communicationShort reports - Short reports on results that are of special interest for the community will be published directly as a Short Communications article and given p…main text ≤ 1,000 words
Policy excerpts from the journal's websiteAI use, Authorship, Conflicts of interest, Data availability, Publication ethics, License & copyright, Open access, Trial registration / reporting guidelines
- AI use Generative AI Images
Please check Springer’s policy on generative AI images and make sure your work adheres to the principles described therein. Back to top
Source ↗Publisher website ·- Authorship Authorship Policy
Authorship should incorporate and should be restricted to those who have contributed substantially to the work in one or more of the following categories: • Conceived of or designed study • Performed research • Analyzed data • Contributed new methods or models • Wrote the paper Back to top
Source ↗Publisher website ·- Conflicts of interest Conflict of interest
Authors must indicate whether or not they have a financial relationship with the organization that sponsored the research. This note should be added in a separate section before the reference list. If no conflict exists, authors should state: The authors declare that they have no conflict of interest.
Source ↗Publisher website ·- Data availability Data availability statements
All original research must include a data availability statement. This statement should explain how to access data supporting the results and analysis in the article, including links/citations to publicly archived datasets analysed or generated during the study. Please see our full policy here. If it is not possible to share research data publicly, for instance when individual privacy could be com…
Source ↗Publisher website ·- Publication ethics Ethical standards
Manuscripts submitted for publication must contain a statement to the effect that all human and animal studies have been approved by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. It should also be stated clearly in the text that all persons gave their informed conse…
Source ↗Publisher website ·- License & copyright Copyright
Open Choice articles do not require transfer of copyright as the copyright remains with the author. In opting for open access, the author(s) agree to publish the article under a Creative Commons license. Details of the OA licences offered to authors can be found on the individual journal website, in the journal's How to publish with us guide. Back to top
Source ↗Publisher website ·- Open access Open access publishing
To find out more about publishing your work Open Access in Archives of Toxicology, including information on fees, funding and licences, visit our Open access publishing page. Back to top
Source ↗Publisher website ·- Trial registration / reporting guidelines Clinical Trial Registration
The World Health Organization (WHO) definition of a clinical trial is "any research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes". The WHO defines health interventions as “A health intervention is an act performed for, with or on behalf of a person or population whose purpose is to ass…
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- Springer Berlin Heidelberg
- Country or region
- GERMANY
- Language
- English
- Frequency
- Monthly
- Founded
- 1930
- ISSN
- 0340-5761
- Electronic ISSN
- 1432-0738
- Latest issue on the website
- Volume 100, Issue 9 (September 2026)
- Official links
- Journal homepage ↗OpenAlex
- Submission system ↗Publisher website
- Author guidelines ↗LetPub
FAQ
Frequently asked questions about Archives of Toxicology
What CAS zone is Archives of Toxicology in?
In the 2025 upgraded edition of the CAS Journal Ranking, Archives of Toxicology is in Zone 2 of Medicine, and in Zone 1 of the minor category Toxicology. In the 2026 Xinrui edition it is in Zone 2 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Archives of Toxicology?
The latest impact factor listed by LetPub is 11; CiteScore 12.7, h-index 184.
How long does peer review take at Archives of Toxicology?
Based on the dates recorded on 116 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 68 days (interquartile range 47–100 days); authors report an average review time of about 1.5 months; the community-reported acceptance is “about 25%”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
What are the manuscript requirements of Archives of Toxicology?
According to the journal's author guidelines: Abstract: 150–250 words; Keywords: ≥ 4; Suggested reviewers: Optional; Cover letter: Required. A model extracted these from the author guidelines and each was checked against the text; check the latest version on the journal's website before submitting.
Where are the editorial board members of Archives of Toxicology based?
Of the 42 board members whose country the journal's board page names, 5 (about 12%) are in mainland China; the countries named most often are Germany (16), Mainland China (5) and United States (3). Counted from the institutions listed on the board page; for reference only.
Which databases index Archives of Toxicology?
According to LetPub and DOAJ records, Archives of Toxicology is indexed in SCIE and Scopus. The journal's website also lists MEDLINE, Embase, CAS, CAB Abstracts and Current Contents; that list has not been checked against each database.
Is Archives of Toxicology open access, and what is the APC?
Archives of Toxicology is a hybrid journal. For open-access publication: APC about USD 5,690.
Sources and updates
The facts on this page come from LetPub, OpenAlex, Publisher website; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .