Journal profile · MEDICINE, RESEARCH & EXPERIMENTAL

Wiley Interdisciplinary Reviews-Systems Biology and Medicine

ISSN 1939-5094 · eISSN 2692-9368 · John Wiley and Sons Inc. · UNITED STATES · Founded 2009

Wiley Interdisciplinary Reviews-Systems Biology and Medicine: impact factor 7.94; hybrid open access; APC about USD 4,000; median 156 days to acceptance (11 articles, last 24 months); acceptance rate 32% (journal website); 6 articles a year; indexed in Scopus.

Impact factor7.94Latest value listed by LetPub
CAS zone—Not in the CAS Journal Ranking
Review time156 daysMedian, submission to acceptance · 11 articles, last 24 months · PubMed
APCUSD 4,000Hybrid journal: charged only for open-access articles
Acceptance32%From the journal's website (2025)
Articles per year6LetPub annual count

Scope

Aims, scope and focus

Wiley Interdisciplinary Reviews-Systems Biology and Medicine is published by John Wiley and Sons Inc.. By OpenAlex counts of its recent articles, its largest topics are Gene Regulatory Network Analysis, Bioinformatics and Genomic Networks and Microbial Metabolic Engineering and Bioproduction, together about 27.7% of its articles. Its main subfields are Molecular Biology. (generated from OpenAlex topic counts and CAS ranking data)

The Wiley Interdisciplinary Reviews (WIREs) series combines features of encyclopedic reference works and review journals. They are designed to serve as interdisciplinary resources across health, life, physical, and social science communities. Our goal is to help researchers save valuable time and stay current in their field and complementary fields with review articles that synthesize key findings from the growing number of primary research articles published daily.

From the journal's Aims & Scope

Research area (LetPub): MEDICINE, RESEARCH & EXPERIMENTAL

Editor-in-chief Roxana DeleanuPublisher website

Editorial board by country: 1 in mainland China (about 8%); most named United States 7, Austria 2, Mainland China 1, United Kingdom 1, Spain 1 (13 members with a country) Editorial board ↗Publisher website ·

Main research topics OpenAlex counts of recent articles; shares are approximate

  1. Gene Regulatory Network AnalysisBiochemistry, Genetics and Molecular Biology13.4%
  2. Bioinformatics and Genomic NetworksBiochemistry, Genetics and Molecular Biology9.2%
  3. Microbial Metabolic Engineering and BioproductionBiochemistry, Genetics and Molecular Biology5%
  4. Cellular Mechanics and InteractionsBiochemistry, Genetics and Molecular Biology4.7%
  5. Genomics and Chromatin DynamicsBiochemistry, Genetics and Molecular Biology4.5%
  6. RNA Research and SplicingBiochemistry, Genetics and Molecular Biology4.4%
  7. Epigenetics and DNA MethylationBiochemistry, Genetics and Molecular Biology4.2%
  8. Mathematical Biology Tumor GrowthMathematics4%

Rankings & indexing

CAS ranking and database indexing

CAS Journal Ranking

CAS Journal Ranking, upgraded edition (March 2025)Not covered

Not covered by this edition.

CAS Xinrui Journal Ranking (March 2026)Not covered

Not covered by this edition.

CAS Journal Ranking, previous upgraded edition (December 2023)Not covered

Not covered by this edition.

Database indexing

ScopusLetPub

International journal early-warning lists: not listed in any editionLetPub

Indexing the journal's website claims

Web of ScienceMEDLINEPubMedCASPublisher website

As the journal's website lists them, not checked against each database; for Web of Science editions the records above apply.

Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.

Metrics

Impact metrics and publication volume

Impact

Impact factor
7.94LetPub ·
Impact factor (publisher)
5.4Publisher website ·
Impact factor (publisher) 2025
5.4Publisher website ·
CiteScore 2026-06
18.4LetPub ·
CiteScore (publisher)
15Publisher website ·
CiteScore (publisher) 2025
15Publisher website ·
SJR 2026-06
1.71LetPub ·
SNIP 2026-06
1.97LetPub ·
h-index
43LetPub ·
h-index
84OpenAlex ·
i10-index
363OpenAlex ·
2-year mean citedness
0OpenAlex ·
Share of gold OA articles
29.03%LetPub ·

Volume

Articles per year (publisher)
2,021Publisher website ·
Articles per year (publisher) 2025
6Publisher website ·
Downloads per year (publisher) 2025
162,100Publisher website ·

Articles by year OpenAlex count · 570 in total · the current year is incomplete

YearArticlesOpen accessCitations
2021100

Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.

Review & acceptance

Review time and acceptance

Review time from article dates manuscript dates registered with PubMed · to

156 daysMedian, submission to acceptance · P25–P75 88 days – 227 days

Acceptance to online
median 38 days (1 articles)
Submission to online
median 428 days
Sample
11 articles with submission and acceptance dates (13 in the window); the latest was accepted on

Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".

Other sources

Average review time (community reports)
over 12 weeksLetPub ·
Acceptance rate (publisher)
32%Publisher website ·
Acceptance rate (publisher) 2025
32%Publisher website ·
Submission to first decision
135 daysPublisher website ·
Submission to first decision 2025
135 daysPublisher website ·
Submission to acceptance 2025
192 daysPublisher website ·
Acceptance to publication 2025
19 daysPublisher website ·
Submission to publication
135 daysPublisher website ·
Peer review
Single anonymous peer reviewPublisher website

Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.

Fees & open access

APC and open-access policy

Hybrid open accessLetPub

A subscription journal in which authors can pay to publish their article open access.

SourceAPCFee waiverLicenseObserved
OpenAlexUSD 4,000 / EUR 3,300 / GBP 2,700——
Publisher websiteYes, amount not published——

A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.

Other charges and waivers (author guidelines)

Page charges
No page charges

The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.

Submission

Article types and submission policies (journal website)

What to prepare2 items from the author guidelines
Reference style
APA
Graphical abstract
Required
Publisher website · model-extracted, each line checked against the text
Article types accepted4
  1. advanced reviewADVANCED REVIEWLength not stated
  2. focus articleFOCUS ARTICLELength not stated
  3. research articleResearch ArticleLength not stated
  4. review articleReview ArticleLength not stated
Publisher website
Policy excerpts from the journal's websiteAI use, Authorship, Data availability, Publication ethics, License & copyright, Open access, Peer review, Self-archiving
AI use

AI tools cannot be authors; use must be described in Methods or Acknowledgements. Model summary

Artificial Intelligence Generated Content (AIGC) tools—such as ChatGPT and others based on large language models (LLMs)—cannot be considered capable of initiating an original piece of research without direction by human authors.

Source ↗Publisher website ·
Authorship

No page charges, color charges, or publication fees for a standard article. Model summary

There are no page charges, color charges, or publication fees for a standard article.

Source ↗Publisher website ·
Data availability

Data sharing: FORCE11 Data Citation Principles endorsed; data availability statement required. Model summary

WIREs has endorsed the FORCE11 Data Citation Principles and is implementing an Expects Data Sharing policy. We require a data availability statement for each article

Source ↗Publisher website ·
Publication ethics Publication Ethics and Malpractice Statement

The WIREs adhere strongly to the Core Practices of the Committee on Publication Ethics (COPE). All instances of publishing misconduct, including, but not limited to, plagiarism, data fabrication, image/data manipulation to falsify/enhance results, etc. will result in rejection/retraction of the manuscript in question.

Source ↗Publisher website ·
License & copyright Open Access Licensing and Copyright

Open Access articles are published under the terms of the Creative Commons Attribution License. The CC-BY license permits commercial and non-commercial re-use of an open access article, as long as the author is properly attributed. WIREs journals offer CC BY, CC BY-NC, and CC BY-NC-ND licensing options.

Source ↗Publisher website ·
Open access Gold Open Access

Open access licensing options: CC BY, CC BY-NC, CC BY-NC-ND. Model summary

WIREs journals offer authors the chance to publish their articles open access: immediately freely available to read, download, and share. Read More Article Publication Charges For article publication charges (APCs) please see the 'Open Access' section in the 'About' tab of each individual journal. Authors who receive funding from an agency or institution with a Wiley Open Access Account do not pay…

Source ↗Publisher website ·
Peer review Peer Review

Peer review: single anonymized, two reviewers per manuscript plus editorial review. Model summary

WIREs is participating in a pilot of the NISO Working Group on Peer Review Terminology. Standardizing the terminology across journals and publishers used to describe peer review practices helps make the peer review process for articles and journals more transparent, and it will enable the community to better assess and compare peer review practices between different journals. More Information Taxo…

Source ↗Publisher website ·
Self-archiving Green Open Access

PubMed Central For authors who are funded by the NIH or a PMC/Europe PMC partner and have indicated so during submission, Wiley will deposit the manuscript to the NIH Manuscript System upon publication. Authors should receive an email from NIHMS with instructions on completing the system checks before the article is assigned a PMCID. (If not, authors can email the production editor to obtain the N…

Source ↗Publisher website ·

Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.

Profile

Publication details and official links

Publisher
John Wiley and Sons Inc.
Country or region
UNITED STATES
Language
English
Founded
2009
ISSN
1939-5094
Print ISSN
2692-9368
Electronic ISSN
2692-9368
Latest issue on the website
Volume 18, Issue 4 (August 2026)
Official links

FAQ

Frequently asked questions about Wiley Interdisciplinary Reviews-Systems Biology and Medicine

What is the impact factor of Wiley Interdisciplinary Reviews-Systems Biology and Medicine?

The latest impact factor listed by LetPub is 7.94; CiteScore 18.4, h-index 84.

How long does peer review take at Wiley Interdisciplinary Reviews-Systems Biology and Medicine?

Based on the dates recorded on 11 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 156 days (interquartile range 88–227 days); authors report an average review time of over 12 weeks; the journal's website gives an acceptance rate of 32% (2025). Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.

What are the manuscript requirements of Wiley Interdisciplinary Reviews-Systems Biology and Medicine?

According to the journal's author guidelines: Reference style: APA; Graphical abstract: Required. A model extracted these from the author guidelines and each was checked against the text; check the latest version on the journal's website before submitting.

Where are the editorial board members of Wiley Interdisciplinary Reviews-Systems Biology and Medicine based?

Of the 13 board members whose country the journal's board page names, 1 (about 8%) are in mainland China; the countries named most often are United States (7), Austria (2) and Mainland China (1). Counted from the institutions listed on the board page; for reference only.

Which databases index Wiley Interdisciplinary Reviews-Systems Biology and Medicine?

According to LetPub and DOAJ records, Wiley Interdisciplinary Reviews-Systems Biology and Medicine is indexed in Scopus. The journal's website also lists Web of Science, MEDLINE, PubMed and CAS; that list has not been checked against each database.

Is Wiley Interdisciplinary Reviews-Systems Biology and Medicine open access, and what is the APC?

Wiley Interdisciplinary Reviews-Systems Biology and Medicine is a hybrid journal. For open-access publication: APC about USD 4,000.

Sources and updates

The facts on this page come from LetPub, Publisher website, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .