Journal profile · BIOCHEMISTRY & MOLECULAR BIOLOGY-CELL BIOLOGY
Science Signaling
ISSN 1945-0877 · eISSN 1937-9145 · American Association for the Advancement of Science · UNITED STATES
Science Signaling: CAS Zone 1 · Biology (2025 upgraded edition, Top journal); impact factor 6.89; subscription journal; 135 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
Science Signaling is published by American Association for the Advancement of Science and is in Zone 1 of Biology in the CAS Journal Ranking (2025 upgraded edition, Top journal). By OpenAlex counts of its recent articles, its largest topics are Immune Cell Function and Interaction, Receptor Mechanisms and Signaling and T-cell and B-cell Immunology, together about 19.4% of its articles. Its main subfields are Immunology and Molecular Biology. (generated from OpenAlex topic counts and CAS ranking data)
Uncovering mechanisms in biology, gaining insights into physiology and disease Science Signaling is a weekly, online multidisciplinary journal for the life sciences. The aim of the journal editors is to publish studies that uncover the basic mechanisms that underlie biological processes across all organisms. Particular emphasis is placed on studies that provide new insights into physiology; delineate aberrant mechanisms that cause disease; identify new potential therapeutic targets and strategies; and characterize the effects of drugs in vitro and in vivo.
Source: LetPub
Research area (LetPub): BIOCHEMISTRY & MOLECULAR BIOLOGY-CELL BIOLOGY
Main research topics OpenAlex counts of recent articles; shares are approximate
- Immune Cell Function and InteractionImmunology and Microbiology7%
- Receptor Mechanisms and SignalingBiochemistry, Genetics and Molecular Biology7%
- T-cell and B-cell ImmunologyImmunology and Microbiology5.4%
- Neuroscience and Neuropharmacology ResearchNeuroscience5.3%
- Protein Kinase Regulation and GTPase SignalingBiochemistry, Genetics and Molecular Biology5.3%
- Ubiquitin and proteasome pathwaysBiochemistry, Genetics and Molecular Biology5.2%
- Immune Response and InflammationImmunology and Microbiology4.7%
- interferon and immune responsesImmunology and Microbiology4.3%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Biology Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 1 |
| Minor | Biochemistry & Molecular Biology | Zone 2 |
| Minor | Cell Biology | Zone 2 |
Top journal: yesReview journal: no
CAS Xinrui Journal Ranking (March 2026)Biology Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 1 |
| Minor | Biochemistry & Molecular Biology | Zone 1 |
| Minor | Cell Biology | Zone 2 |
Top journal: yesReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Biology Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 1 |
| Minor | Biochemistry & Molecular Biology | Zone 2 |
| Minor | Cell Biology | Zone 2 |
Top journal: yesReview journal: no
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 6.89LetPub ·
- CiteScore 2026-06
- 7.8LetPub ·
- SJR 2026-06
- 2.05LetPub ·
- SNIP 2026-06
- 1.38LetPub ·
- h-index
- 128LetPub ·
- h-index
- 197OpenAlex ·
- i10-index
- 2,453OpenAlex ·
- 2-year mean citedness
- 5.83OpenAlex ·
- Self-citation rate
- 0%LetPub ·
- Share of gold OA articles
- 3.48%LetPub ·
Volume
- Articles per year
- 96LetPub ·
Articles by year OpenAlex count · 9,461 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 102 | 22 | 81 |
| 2025 | 135 | 64 | 677 |
| 2024 | 145 | 49 | 1,470 |
| 2023 | 165 | 72 | 2,531 |
| 2022 | 161 | 64 | 3,540 |
| 2021 | 172 | 85 | 5,035 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with Crossref
Not usableThis publisher's "received" date is mostly when the revised manuscript arrived (26% of articles were "accepted" within 3 days), so it cannot measure review time
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Subscription journalLetPub
A subscription journal: articles are read by subscription or purchase, and authors usually pay no publication charge.
No source has fee information yet; check the journal's website.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Profile
Publication details and official links
- Publisher
- American Association for the Advancement of Science
- Country or region
- UNITED STATES
- Language
- English
- ISSN
- 1945-0877
- Electronic ISSN
- 1937-9145
- Official links
- Journal homepage ↗OpenAlex
- Submission system ↗LetPub
FAQ
Frequently asked questions about Science Signaling
What CAS zone is Science Signaling in?
In the 2025 upgraded edition of the CAS Journal Ranking, Science Signaling is in Zone 1 of Biology, and in Zone 2 of the minor category Biochemistry & Molecular Biology / Cell Biology; it is a Top journal. In the 2026 Xinrui edition it is in Zone 1 of Biology. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Science Signaling?
The latest impact factor listed by LetPub is 6.89; CiteScore 7.8, h-index 197.
Which databases index Science Signaling?
According to LetPub and DOAJ records, Science Signaling is indexed in SCIE and Scopus.
Is Science Signaling open access, and what is the APC?
Science Signaling is a subscription journal. Fee information is not available yet; check the journal's website.
Sources and updates
The facts on this page come from LetPub, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .