Journal profile · Biochemical Research Methods
Protein Expression and Purification
ISSN 1046-5928 · eISSN 1096-0279 · Academic Press Inc. · UNITED STATES · Monthly · Founded 1990
Protein Expression and Purification: CAS Zone 4 · Biology (2025 upgraded edition); impact factor 1.77; hybrid open access; APC about USD 3,680; median 69 days to acceptance (102 articles, last 24 months); community-reported acceptance: easy; 150 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
Protein Expression and Purification is published by Academic Press Inc. and is in Zone 4 of Biology in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Monoclonal and Polyclonal Antibodies Research, Viral Infectious Diseases and Gene Expression in Insects and Protein purification and stability, together about 25.8% of its articles. Its main subfields are Molecular Biology. (generated from OpenAlex topic counts and CAS ranking data)
Protein Expression and Purification is an international journal providing a forum for the dissemination of new information on protein expression, extraction, purification, characterization, and/or applications using conventional biochemical and/or modern molecular biological approaches and methods, which are of broad interest to the field. The journal does not typically publish repetitive examples of protein expression and purification involving standard, well-established, methods. However, exceptions might include studies on important and/or difficult to express and/or purify proteins and/or studies that include extensive protein characterization, which provide new, previously unpublished information.
From the journal's Aims & Scope
Research area (LetPub): Biochemical Research Methods
Editor-in-chief Adrian Velazquez-CampoyPublisher website
Editorial board by country: 4 in mainland China (about 8%); most named United States 23, Mainland China 4, Germany 4, United Kingdom 2, Japan 2 (48 members with a country) Editorial board ↗Publisher website ·
Main research topics OpenAlex counts of recent articles; shares are approximate
- Monoclonal and Polyclonal Antibodies ResearchMedicine10.1%
- Viral Infectious Diseases and Gene Expression in InsectsBiochemistry, Genetics and Molecular Biology8.4%
- Protein purification and stabilityBiochemistry, Genetics and Molecular Biology7.4%
- Bacterial Genetics and BiotechnologyBiochemistry, Genetics and Molecular Biology5.8%
- RNA and protein synthesis mechanismsBiochemistry, Genetics and Molecular Biology5.5%
- Glycosylation and Glycoproteins ResearchBiochemistry, Genetics and Molecular Biology5.3%
- Enzyme Production and CharacterizationBiochemistry, Genetics and Molecular Biology5.1%
- Enzyme Structure and FunctionMaterials Science5%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Biology Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 4 |
| Minor | Biochemical Research Methods | Zone 4 |
| Minor | Biochemistry & Molecular Biology | Zone 4 |
| Minor | Biotechnology & Applied Microbiology | Zone 4 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Biology Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 4 |
| Minor | Biochemical Research Methods | Zone 4 |
| Minor | Biochemistry & Molecular Biology | Zone 4 |
| Minor | Biotechnology & Applied Microbiology | Zone 4 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Biology Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 4 |
| Minor | Biochemical Research Methods | Zone 4 |
| Minor | Biochemistry & Molecular Biology | Zone 4 |
| Minor | Biotechnology & Applied Microbiology | Zone 4 |
Top journal: noReview journal: no
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 1.77LetPub ·
- Impact factor (publisher)
- 1.8Publisher website ·
- CiteScore 2026-06
- 3LetPub ·
- CiteScore (publisher)
- 3Publisher website ·
- SJR 2026-06
- 0.42LetPub ·
- SNIP 2026-06
- 0.52LetPub ·
- h-index
- 81LetPub ·
- h-index
- 112OpenAlex ·
- i10-index
- 3,789OpenAlex ·
- 2-year mean citedness
- 2.01OpenAlex ·
- Self-citation rate
- 5.6%LetPub ·
- Share of gold OA articles
- 13.24%LetPub ·
Volume
- Articles per year
- 136LetPub ·
Articles by year OpenAlex count · 6,709 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 108 | 29 | 23 |
| 2025 | 150 | 34 | 212 |
| 2024 | 144 | 41 | 572 |
| 2023 | 117 | 44 | 438 |
| 2022 | 119 | 35 | 643 |
| 2021 | 151 | 32 | 1,514 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with PubMed · to
69 daysMedian, submission to acceptance · P25–P75 52 days – 91 days
- Acceptance to online
- median 2 days (102 articles)
- Submission to online
- median 73 days
- Sample
- 102 articles with submission and acceptance dates (311 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Average review time (community reports)
- about 1 monthLetPub ·
- Average acceptance (community reports)
- EasyLetPub ·
- Submission to first decision
- 2 daysPublisher website ·
- First decision after review
- 30 daysPublisher website ·
- Submission to acceptance
- 65 daysPublisher website ·
- Acceptance to publication
- 2 daysPublisher website ·
- Peer review
- Single anonymous peer reviewPublisher website
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Hybrid open accessLetPub
A subscription journal in which authors can pay to publish their article open access.
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| OpenAlex | USD 3,680 / EUR 3,440 / GBP 2,950 / JPY 456,430 | — | — | |
| Publisher website | USD 3,610 | — | — |
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
Article types accepted5
- primary research articlesProtein Expression and Purification publishes primary research articles, short reports, and reviews.Length not stated
- registered reportThis journal supports Registered Reports as article type, allowing you to have your research reviewed and pre-registered prior to conducting your experiments. P…Length not stated
- registered reportsThis journal supports Registered Reports as article type, allowing you to have your research reviewed and pre-registered prior to conducting your experiments.Length not stated
- review articlesReview articles providing a broad coverage of important advances, emerging areas of interest, and other topics relevant to the field of protein expression and p…Length not stated
- short reportsShort reports are also published in Protein Expression and Purification.Length not stated
Policy excerpts from the journal's websiteAI use, Authorship, Conflicts of interest, License & copyright, Open access, Peer review, Preprints
- AI use Declaration of generative AI use
Authors must declare the use of generative AI tools in the manuscript preparation process upon submission of the paper.Generative AI and AI-assisted technologies (“AI tools”) have been rapidly adopted in research and scholarly publishing, offering significant benefits while requiring clear standards for responsible and transparent use.Authors preparing a manuscript for this journal may use AI tool…
Source ↗Publisher website ·- Authorship Group authorship
Group authorship refers to the attribution of an article to a defined and named group of authors whose members have contributed to the work. Examples include research consortia, clinical trial groups, collaborative networks, task forces or working groups, expert panels or consensus groups, and participatory research groups. Group authorship must be declared on the title page at submission. When av…
Source ↗Publisher website ·- Conflicts of interest Declaration of competing interests
All authors must disclose any financial and personal relationships with other people or organizations that could inappropriately influence or bias their work. Examples of potential competing interests include:EmploymentConsultanciesStock ownershipHonorariaPaid expert testimonyPatent applications or registrationsGrants or any other fundingAffiliation with the journal as an Editor or Advisory Board …
Source ↗Publisher website ·- License & copyright License options
Authors will be offered open access user license options which will determine how you, and third parties, can reuse your open access article. We advise that you review these options and any funding body license requirements before selecting a license option.
Source ↗Publisher website ·- Open access Open access
We refer you to our open access information page to learn about open access options for this journal.
Source ↗Publisher website ·- Peer review Peer review
Peer review type: single anonymized review process. Model summary
This journal follows a single anonymized review process. Your submission will initially be assessed by our editors. If your submission is deemed suitable, it will typically be sent to be reviewed by a minimum of one reviewer for an independent expert assessment of the scientific quality. The decision as to whether your article is accepted or rejected for publication will be made by our editors.Rea…
Source ↗Publisher website ·- Preprints Preprints
Preprint sharing allowed; will not count as prior publication. Model summary
Preprint sharingAuthors may share preprints in line with Elsevier's article sharing policy. Sharing preprints, such as on a preprint server, will not count as prior publication.We advise you to read our policy on multiple, redundant or concurrent publication.
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- Academic Press Inc.
- Country or region
- UNITED STATES
- Language
- English
- Frequency
- Monthly
- Founded
- 1990
- ISSN
- 1046-5928
- Electronic ISSN
- 1096-0279
- Official links
- Journal homepage ↗OpenAlex
- Submission system ↗Publisher website
- Special issues ↗Publisher website
FAQ
Frequently asked questions about Protein Expression and Purification
What CAS zone is Protein Expression and Purification in?
In the 2025 upgraded edition of the CAS Journal Ranking, Protein Expression and Purification is in Zone 4 of Biology, and in Zone 4 of the minor category Biochemical Research Methods / Biochemistry & Molecular Biology / Biotechnology & Applied Microbiology. In the 2026 Xinrui edition it is in Zone 4 of Biology. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Protein Expression and Purification?
The latest impact factor listed by LetPub is 1.77; CiteScore 3, h-index 112.
How long does peer review take at Protein Expression and Purification?
Based on the dates recorded on 102 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 69 days (interquartile range 52–91 days); authors report an average review time of about 1 month; the community-reported acceptance is “Easy”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
Where are the editorial board members of Protein Expression and Purification based?
Of the 48 board members whose country the journal's board page names, 4 (about 8%) are in mainland China; the countries named most often are United States (23), Mainland China (4) and Germany (4). Counted from the institutions listed on the board page; for reference only.
Which databases index Protein Expression and Purification?
According to LetPub and DOAJ records, Protein Expression and Purification is indexed in SCIE and Scopus.
Is Protein Expression and Purification open access, and what is the APC?
Protein Expression and Purification is a hybrid journal. For open-access publication: APC about USD 3,680.
Sources and updates
The facts on this page come from LetPub, Publisher website, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-26). Last updated: .