Journal profile · Biochemistry & Molecular Biology

Protein and Peptide Letters

ISSN 0929-8665 · eISSN 1875-5305 · Bentham Science Publishers B.V. · NETHERLANDS · Bimonthly · Founded 1994

Protein and Peptide Letters: CAS Zone 4 · Biology (2025 upgraded edition); impact factor 2.49; hybrid open access; median 84 days to acceptance (71 articles, last 24 months); community-reported acceptance: easy; 58 articles in 2025; indexed in SCIE and Scopus.

Impact factor2.49Latest value listed by LetPub
CAS zoneZone 4 · Biology2025 upgraded edition, major category · 2026 Xinrui edition Zone 4 · Biology
Review time84 daysMedian, submission to acceptance · 71 articles, last 24 months · Crossref
APC—No source gives fee information
AcceptanceEasyCommunity average
Articles per year582025 · OpenAlex count

Scope

Aims, scope and focus

Protein and Peptide Letters is published by Bentham Science Publishers B.V. and is in Zone 4 of Biology in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Protein Structure and Dynamics, Chemical Synthesis and Analysis and Enzyme Structure and Function, together about 23.2% of its articles. Its main subfields are Molecular Biology. (generated from OpenAlex topic counts and CAS ranking data)

Protein & Peptide Letters publishes letters, original research papers, mini-reviews and guest edited issues in all important aspects of protein and peptide research, including structural studies, advances in recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, and drug design. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallization and preliminary structure determination of biologically important proteins are considered only if they include significant new approaches or deal with proteins of immediate importance, and preliminary structure determinations of biologically important proteins. Purely theoretical/review papers should provide new insight into the principles of protein/peptide structure and function. Manuscripts describing computational work should include some experimental data to provide confirmation of the results of calculations. Protein & Peptide Letters focuses on: Structure Studies Advances in Recombinant Expression Drug Design Chemical Synthesis Function Pharmacology Enzymology Conformational Analysis Immunology Biotechnology Protein Engineering Protein Folding Sequencing Molecular Recognition Purification and Analysis

Source: LetPub

Research area (LetPub): Biochemistry & Molecular Biology

Main research topics OpenAlex counts of recent articles; shares are approximate

  1. Protein Structure and DynamicsBiochemistry, Genetics and Molecular Biology9%
  2. Chemical Synthesis and AnalysisBiochemistry, Genetics and Molecular Biology7.3%
  3. Enzyme Structure and FunctionMaterials Science6.9%
  4. Machine Learning in BioinformaticsBiochemistry, Genetics and Molecular Biology6.8%
  5. Antimicrobial Peptides and ActivitiesImmunology and Microbiology6.6%
  6. Enzyme Production and CharacterizationBiochemistry, Genetics and Molecular Biology5.6%
  7. Glycosylation and Glycoproteins ResearchBiochemistry, Genetics and Molecular Biology5.2%
  8. Monoclonal and Polyclonal Antibodies ResearchMedicine5.1%

Rankings & indexing

CAS ranking and database indexing

CAS Journal Ranking

CAS Journal Ranking, upgraded edition (March 2025)Biology Zone 4
LevelCategoryZone
MajorBiologyZone 4
MinorBiochemistry & Molecular BiologyZone 4

Top journal: noReview journal: no

CAS Xinrui Journal Ranking (March 2026)Biology Zone 4
LevelCategoryZone
MajorBiologyZone 4
MinorBiochemistry & Molecular BiologyZone 4

Top journal: noReview journal: not marked

CAS Journal Ranking, previous upgraded edition (December 2023)Biology Zone 4
LevelCategoryZone
MajorBiologyZone 4
MinorBiochemistry & Molecular BiologyZone 4

Top journal: noReview journal: no

Database indexing

SCIEScopusLetPub

International journal early-warning lists: not listed in any editionLetPub

Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.

Metrics

Impact metrics and publication volume

Impact

Impact factor
2.49LetPub ·
CiteScore 2026-06
2.8LetPub ·
SJR 2026-06
0.47LetPub ·
SNIP 2026-06
0.43LetPub ·
h-index
50LetPub ·
h-index
75OpenAlex ·
i10-index
1,292OpenAlex ·
2-year mean citedness
4.35OpenAlex ·
Self-citation rate
4%LetPub ·
Share of gold OA articles
5.79%LetPub ·

Volume

Articles per year
68LetPub ·

Articles by year OpenAlex count · 3,881 in total · the current year is incomplete

YearArticlesOpen accessCitations
2026471117
2025584235
2024735522
20231029565
20221139610
202110412725

Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.

Review & acceptance

Review time and acceptance

Review time from article dates manuscript dates registered with Crossref · to

84 daysMedian, submission to acceptance · P25–P75 67 days – 108 days

Acceptance to online
median 154 days (71 articles)
Submission to online
median 241 days
Sample
71 articles with submission and acceptance dates (134 in the window); the latest was accepted on

Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".

Other sources

Average review time (community reports)
about 2 monthsLetPub ·
Average acceptance (community reports)
EasyLetPub ·

Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.

Fees & open access

APC and open-access policy

Hybrid open accessLetPub

A subscription journal in which authors can pay to publish their article open access.

No source has fee information yet; check the journal's website.

A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.

The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.

Profile

Publication details and official links

Publisher
Bentham Science Publishers B.V.
Country or region
NETHERLANDS
Language
English
Frequency
Bimonthly
Founded
1994
ISSN
0929-8665
Electronic ISSN
1875-5305
Official links

FAQ

Frequently asked questions about Protein and Peptide Letters

What CAS zone is Protein and Peptide Letters in?

In the 2025 upgraded edition of the CAS Journal Ranking, Protein and Peptide Letters is in Zone 4 of Biology, and in Zone 4 of the minor category Biochemistry & Molecular Biology. In the 2026 Xinrui edition it is in Zone 4 of Biology. Zones from different editions, and from major and minor categories, are not interchangeable.

What is the impact factor of Protein and Peptide Letters?

The latest impact factor listed by LetPub is 2.49; CiteScore 2.8, h-index 75.

How long does peer review take at Protein and Peptide Letters?

Based on the dates recorded on 71 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 84 days (interquartile range 67–108 days); authors report an average review time of about 2 months; the community-reported acceptance is “Easy”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.

Which databases index Protein and Peptide Letters?

According to LetPub and DOAJ records, Protein and Peptide Letters is indexed in SCIE and Scopus.

Is Protein and Peptide Letters open access, and what is the APC?

Protein and Peptide Letters is a hybrid journal. Fee information is not available yet; check the journal's website.

Sources and updates

The facts on this page come from LetPub, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-26). Last updated: .