Journal profile · Biochemical Research Methods

Methods in Enzymology

ISSN 0076-6879 · eISSN 1557-7988 · Academic Press Inc. · UNITED STATES · Irregular · Founded 1955

Methods in Enzymology: impact factor 1.26; subscription journal; review 3–6 weeks (community reports); community-reported acceptance: easy; 374 articles in 2025; indexed in Scopus.

Impact factor1.26Latest value listed by LetPub
CAS zone—Not in the CAS Journal Ranking
Review time3–6 weeksCommunity average
APC—No source gives fee information
AcceptanceEasyCommunity average
Articles per year3742025 · OpenAlex count

Scope

Aims, scope and focus

Methods in Enzymology is published by Academic Press Inc.. By OpenAlex counts of its recent articles, its largest topics are RNA and protein synthesis mechanisms, Enzyme Structure and Function and Glycosylation and Glycoproteins Research, together about 22.3% of its articles. Its main subfields are Molecular Biology. (generated from OpenAlex topic counts and CAS ranking data)

The critically acclaimed laboratory standard since 1955, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Each volume is eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 650 volumes the series contains much material still relevant today and is truly an essential publication for researchers in all fields of life sciences, including microbiology, biochemistry, cancer research and genetics-just to name a few. Its readership includes Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists. Multiple Nobel Laureates have edited or contributed to volumes of MIE and each volume and chapter includes not only background knowledge but also specific research techniques, detailed experimental procedures and methods. Video elements are also present.

From the journal's Aims & Scope

Research area (LetPub): Biochemical Research Methods

Main research topics OpenAlex counts of recent articles; shares are approximate

  1. RNA and protein synthesis mechanismsBiochemistry, Genetics and Molecular Biology9.4%
  2. Enzyme Structure and FunctionMaterials Science7%
  3. Glycosylation and Glycoproteins ResearchBiochemistry, Genetics and Molecular Biology5.9%
  4. Monoclonal and Polyclonal Antibodies ResearchMedicine4.9%
  5. Metabolism and Genetic DisordersBiochemistry, Genetics and Molecular Biology4.6%
  6. Protein Structure and DynamicsBiochemistry, Genetics and Molecular Biology4.5%
  7. Photosynthetic Processes and MechanismsBiochemistry, Genetics and Molecular Biology4.2%
  8. Amino Acid Enzymes and MetabolismBiochemistry, Genetics and Molecular Biology4.2%

Rankings & indexing

CAS ranking and database indexing

CAS Journal Ranking

CAS Journal Ranking, upgraded edition (March 2025)Not covered

Not covered by this edition.

CAS Xinrui Journal Ranking (March 2026)Not covered

Not covered by this edition.

CAS Journal Ranking, previous upgraded edition (December 2023)Not covered

Not covered by this edition.

Database indexing

ScopusLetPub

International journal early-warning lists: not listed in any editionLetPub

Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.

Metrics

Impact metrics and publication volume

Impact

Impact factor
1.26LetPub ·
CiteScore 2026-06
2LetPub ·
SJR 2026-06
0.39LetPub ·
SNIP 2026-06
0.32LetPub ·
h-index
152LetPub ·
h-index
380OpenAlex ·
i10-index
15,396OpenAlex ·
2-year mean citedness
0.76OpenAlex ·
Share of gold OA articles
0%LetPub ·

Volume

Articles per year
260LetPub ·

Articles by year OpenAlex count · 30,033 in total · the current year is incomplete

YearArticlesOpen accessCitations
20262591616
202537459197
202438088553
202324246626
20224161001,987
2021310772,055

Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.

Review & acceptance

Review time and acceptance

Average review time (community reports)
3–6 weeksLetPub ·
Average acceptance (community reports)
EasyLetPub ·

Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.

Fees & open access

APC and open-access policy

Subscription journalLetPub

A subscription journal: articles are read by subscription or purchase, and authors usually pay no publication charge.

No source has fee information yet; check the journal's website.

The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.

Profile

Publication details and official links

Publisher
Academic Press Inc.
Country or region
UNITED STATES
Language
English
Frequency
Irregular
Founded
1955
ISSN
0076-6879
Electronic ISSN
1557-7988
Official links

FAQ

Frequently asked questions about Methods in Enzymology

What is the impact factor of Methods in Enzymology?

The latest impact factor listed by LetPub is 1.26; CiteScore 2, h-index 380.

How long does peer review take at Methods in Enzymology?

Authors report an average review time of 3–6 weeks; the community-reported acceptance is “Easy”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.

Which databases index Methods in Enzymology?

According to LetPub and DOAJ records, Methods in Enzymology is indexed in Scopus.

Is Methods in Enzymology open access, and what is the APC?

Methods in Enzymology is a subscription journal. Fee information is not available yet; check the journal's website.

Sources and updates

The facts on this page come from LetPub, OpenAlex, Publisher website; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .