Journal profile · Biochemical Research Methods

Methods

ISSN 1046-2023 · eISSN 1095-9130 · Academic Press Inc. · UNITED STATES · Monthly · Founded 1990

Methods: CAS Zone 3 · Biology (2025 upgraded edition); impact factor 3.39; hybrid open access; APC about USD 3,600; median 91 days to acceptance (98 articles, last 24 months); community-reported acceptance: fairly easy; 186 articles in 2025; indexed in SCIE and Scopus.

Impact factor3.39Latest value listed by LetPub
CAS zoneZone 3 · Biology2025 upgraded edition, major category · 2026 Xinrui edition Zone 3 · Biology
Review time91 daysMedian, submission to acceptance · 98 articles, last 24 months · PubMed
APCUSD 3,600Hybrid journal: charged only for open-access articles
AcceptanceFairly easyCommunity average
Articles per year1862025 · OpenAlex count

Scope

Aims, scope and focus

Methods is published by Academic Press Inc. and is in Zone 3 of Biology in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are RNA and protein synthesis mechanisms, RNA Research and Splicing and RNA modifications and cancer, together about 25.7% of its articles. Its main subfields are Molecular Biology. (generated from OpenAlex topic counts and CAS ranking data)

Methods publishes original review and research articles that cover emerging methodology in many areas of life and health sciences. The research areas covered by Methods include, but are not limited to,• Biochemistry and biophysics • Cell, molecular, and developmental biology and genetics • Computational biology and bioinformatics • Medicinal chemistry, biological chemistry, and biophysical chemistry • Microbiology, immunology, and virology • Physiology and pathology • Bioengineering, biomedical engineering, and biochemical engineering • Biomaterials, natural products, and materials science • Therapeutics and diagnostics, biosensors, and devicesMethods publishes original research on methodologies with a significant experimental component. Computational, AI, and machine learning approaches should uncover novel biological insights and must be experimentally validated. Purely theoretical studies or computational work with minimal experimental support are outside the journal’s scope. Methods remains a key resource for advancing innovative, experimentally driven scientific techniques. Review articles are also considered for publication in Methods, and all review manuscripts must accompany 1) a summary of previous reviews on relevant topics and 2) a statement of the timely needs of the review, significant contributions and new insights offered by the submission, and experts’ opinions and perspectives in a new and innovative point of view. These must be provided in the “Highlights” page as well as in the opening section of the manuscript itself. Lacking these components will lead to an administrative rejection of the submission.Methods especially welcomes contributions from Guest Editors or authors who are underrepresented in regard to gender, career stage, or geographical location and contributions focused on underrecognized areas of research.There are several types of issues published by Methods:Thematic issues are organized by a Guest Editor who is a recognized expert in the research area. The Guest Editor may have co-Guest Editors. The issues consist solely of invited review articles or original research articles of high quality by authors with expertise in the field. Issues are devoted to specific methods or a variety of methods to investigate a particular research question, with emphasis on clear descriptions of recent advances. Background information is provided in the articles to further an understanding of the principles underlying the methods. Other sections of the articles include key protocols, comparisons of alternative methods, the advantages and disadvantages of particular methods, guidance on avoiding potential pitfalls, and suggestions for troubleshooting.Geographical, institutional/organizational, and event issues publish articles that cover advances in research methods at universities, research institutes, and scientific societies in a particular geographical region, by a notable institution and society anywhere worldwide, or at a conference of significant interest. These issues are organized by a Guest Editor (sometimes with co-Guest Editors) who is a research leader in the geographical region, at the institution/society, or involved with the event. As in the thematic issues, the articles in these issues consist of concise overviews of methodology, comparisons of alternative methods with advantages and limitations, research questions to give further consideration, and perspectives.Editor's Collections publish non-solicited, high-quality review or research articles in any of the research areas that are within the scope of Methods. It is open for non-invited authors to submit directly to the journal and choose the article type “VSI: Open for all—Editors’ Collection” from the drop-down menu. Similar to the articles in thematic or geographical/institutional/organizational/event issues, these contributions will be handled by the Editor-in-Chief or an Editor, depending on the topic. Nonsolicited articles are usually publ

From the journal's Aims & Scope

Research area (LetPub): Biochemical Research Methods

Editor-in-chief Young Jik KwonPublisher website

Editorial board by country: 4 in mainland China (about 15%); most named United States 12, Mainland China 4, Australia 4, United Kingdom 2, India 1 (26 members with a country) Editorial board ↗Publisher website ·

Main research topics OpenAlex counts of recent articles; shares are approximate

  1. RNA and protein synthesis mechanismsBiochemistry, Genetics and Molecular Biology11.5%
  2. RNA Research and SplicingBiochemistry, Genetics and Molecular Biology7.1%
  3. RNA modifications and cancerBiochemistry, Genetics and Molecular Biology7.1%
  4. Diverse Scientific and Economic StudiesEconomics, Econometrics and Finance5.5%
  5. Advanced biosensing and bioanalysis techniquesBiochemistry, Genetics and Molecular Biology5.3%
  6. Human auditory perception and evaluationEngineering5.2%
  7. Genomics and Chromatin DynamicsBiochemistry, Genetics and Molecular Biology5.2%
  8. CRISPR and Genetic EngineeringBiochemistry, Genetics and Molecular Biology4.9%

Rankings & indexing

CAS ranking and database indexing

CAS Journal Ranking

CAS Journal Ranking, upgraded edition (March 2025)Biology Zone 3
LevelCategoryZone
MajorBiologyZone 3
MinorBiochemical Research MethodsZone 2
MinorBiochemistry & Molecular BiologyZone 3

Top journal: noReview journal: no

CAS Xinrui Journal Ranking (March 2026)Biology Zone 3
LevelCategoryZone
MajorBiologyZone 3
MinorBiochemical Research MethodsZone 2
MinorBiochemistry & Molecular BiologyZone 3

Top journal: noReview journal: not marked

CAS Journal Ranking, previous upgraded edition (December 2023)Biology Zone 3
LevelCategoryZone
MajorBiologyZone 3
MinorBiochemical Research MethodsZone 3
MinorBiochemistry & Molecular BiologyZone 3

Top journal: noReview journal: no

Database indexing

SCIEScopusLetPub

International journal early-warning lists: not listed in any editionLetPub

Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.

Metrics

Impact metrics and publication volume

Impact

Impact factor
3.39LetPub ·
Impact factor (publisher)
3.6Publisher website ·
CiteScore 2026-06
9.3LetPub ·
CiteScore (publisher)
9.3Publisher website ·
SJR 2026-06
0.82LetPub ·
SNIP 2026-06
0.97LetPub ·
h-index
132LetPub ·
h-index
206OpenAlex ·
i10-index
3,982OpenAlex ·
2-year mean citedness
3.84OpenAlex ·
Self-citation rate
11.1%LetPub ·
Share of gold OA articles
21.64%LetPub ·

Volume

Articles per year
160LetPub ·

Articles by year OpenAlex count · 6,114 in total · the current year is incomplete

YearArticlesOpen accessCitations
20261235048
202518662519
2024191681,352
2023135481,302
2022152502,212
2021188904,901

Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.

Review & acceptance

Review time and acceptance

Review time from article dates manuscript dates registered with PubMed · to

91 daysMedian, submission to acceptance · P25–P75 64 days – 124 days

Acceptance to online
median 2 days (98 articles)
Submission to online
median 94 days
Sample
98 articles with submission and acceptance dates (346 in the window); the latest was accepted on

Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".

Other sources

Average review time (community reports)
3–8 weeksLetPub ·
Average acceptance (community reports)
Fairly easyLetPub ·
Submission to first decision
4 daysPublisher website ·
First decision after review
45 daysPublisher website ·
Submission to acceptance
82 daysPublisher website ·
Acceptance to publication
3 daysPublisher website ·
Peer review
Single anonymous peer reviewPublisher website

Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.

Fees & open access

APC and open-access policy

Hybrid open accessLetPub

A subscription journal in which authors can pay to publish their article open access.

SourceAPCFee waiverLicenseObserved
OpenAlexUSD 3,600 / EUR 3,370 / GBP 2,880 / JPY 446,510——
Publisher websiteUSD 3,590——

A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.

The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.

Submission

Article types and submission policies (journal website)

Article types accepted5
  1. editorialFull-length research articles or reviews.Should you have a Guest Editor proposal or an idea for a thematic or geographical/institutional/event issue (see below)…Length not stated
  2. full-length research articlesFull-length research articles or reviews.Length not stated
  3. research articleFull-length research articles or reviews.Should you have a Guest Editor proposal or an idea for a thematic or geographical/institutional/event issue (see below)…Length not stated
  4. reviewFull-length research articles or reviews.Should you have a Guest Editor proposal or an idea for a thematic or geographical/institutional/event issue (see below)…Length not stated
  5. reviewsFull-length research articles or reviews.Length not stated
Publisher website
Policy excerpts from the journal's websiteAI use, Authorship, Conflicts of interest, License & copyright, Open access, Peer review, Preprints
AI use Declaration of generative AI use

Authors must declare the use of generative AI tools in the manuscript preparation process upon submission of the paper.Generative AI and AI-assisted technologies (“AI tools”) have been rapidly adopted in research and scholarly publishing, offering significant benefits while requiring clear standards for responsible and transparent use.Authors preparing a manuscript for this journal may use AI tool…

Source ↗Publisher website ·
Authorship Group authorship

Group authorship refers to the attribution of an article to a defined and named group of authors whose members have contributed to the work. Examples include research consortia, clinical trial groups, collaborative networks, task forces or working groups, expert panels or consensus groups, and participatory research groups. Group authorship must be declared on the title page at submission. When av…

Source ↗Publisher website ·
Conflicts of interest Declaration of competing interests

All authors must disclose any financial and personal relationships with other people or organizations that could inappropriately influence or bias their work. Examples of potential competing interests include:EmploymentConsultanciesStock ownershipHonorariaPaid expert testimonyPatent applications or registrationsGrants or any other fundingAffiliation with the journal as an Editor or Advisory Board …

Source ↗Publisher website ·
License & copyright License options

Authors will be offered open access user license options which will determine how you, and third parties, can reuse your open access article. We advise that you review these options and any funding body license requirements before selecting a license option.

Source ↗Publisher website ·
Open access Open access

We refer you to our open access information page to learn about open access options for this journal.

Source ↗Publisher website ·
Peer review Peer review

Single anonymized review process Model summary

This journal follows a single anonymized review process. Your submission will initially be assessed by our editors. If your submission is deemed suitable, it will typically be sent to be reviewed by a minimum of two reviewers for an independent expert assessment of the scientific quality. The decision as to whether your article is accepted or rejected for publication will be made by our editors.Re…

Source ↗Publisher website ·
Preprints Preprints

Preprint sharing allowed Model summary

Preprint sharingAuthors may share preprints in line with Elsevier's article sharing policy. Sharing preprints, such as on a preprint server, will not count as prior publication.We advise you to read our policy on multiple, redundant or concurrent publication.

Source ↗Publisher website ·

Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.

Profile

Publication details and official links

Publisher
Academic Press Inc.
Country or region
UNITED STATES
Language
English
Frequency
Monthly
Founded
1990
ISSN
1046-2023
Electronic ISSN
1095-9130
Official links

FAQ

Frequently asked questions about Methods

What CAS zone is Methods in?

In the 2025 upgraded edition of the CAS Journal Ranking, Methods is in Zone 3 of Biology, and in Zone 2 of the minor category Biochemical Research Methods / Biochemistry & Molecular Biology. In the 2026 Xinrui edition it is in Zone 3 of Biology. Zones from different editions, and from major and minor categories, are not interchangeable.

What is the impact factor of Methods?

The latest impact factor listed by LetPub is 3.39; CiteScore 9.3, h-index 206.

How long does peer review take at Methods?

Based on the dates recorded on 98 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 91 days (interquartile range 64–124 days); authors report an average review time of 3–8 weeks; the community-reported acceptance is “Fairly easy”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.

Where are the editorial board members of Methods based?

Of the 26 board members whose country the journal's board page names, 4 (about 15%) are in mainland China; the countries named most often are United States (12), Mainland China (4) and Australia (4). Counted from the institutions listed on the board page; for reference only.

Which databases index Methods?

According to LetPub and DOAJ records, Methods is indexed in SCIE and Scopus.

Is Methods open access, and what is the APC?

Methods is a hybrid journal. For open-access publication: APC about USD 3,600.

Sources and updates

The facts on this page come from LetPub, Publisher website, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-26). Last updated: .