Journal profile · Geriatrics & Gerontology

Mechanisms of Ageing and Development

ISSN 0047-6374 · eISSN 1872-6216 · Elsevier Ireland Ltd · SWITZERLAND · Monthly · Founded 1972

Mechanisms of Ageing and Development: CAS Zone 2 · Medicine (2025 upgraded edition); impact factor 6.45; hybrid open access; APC about USD 4,780; median 89 days to acceptance (103 articles, last 24 months); community-reported acceptance: moderate; 86 articles in 2025; indexed in SCIE and Scopus.

Impact factor6.45Latest value listed by LetPub
CAS zoneZone 2 · Medicine2025 upgraded edition, major category · 2026 Xinrui edition Zone 2 · Medicine
Review time89 daysMedian, submission to acceptance · 103 articles, last 24 months · PubMed
APCUSD 4,780Hybrid journal: charged only for open-access articles
AcceptanceModerateCommunity average
Articles per year862025 · OpenAlex count

Scope

Aims, scope and focus

Mechanisms of Ageing and Development is published by Elsevier Ireland Ltd and is in Zone 2 of Medicine in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Genetics, Aging, and Longevity in Model Organisms, Telomeres, Telomerase, and Senescence and Mitochondrial Function and Pathology, together about 29.9% of its articles. (generated from OpenAlex topic counts and CAS ranking data)

The Official Journal of the European Society of Preventive, Regenerative and Anti-aging Medicine (ESAAM) Mechanisms of Ageing and Development is a multidisciplinary journal aimed at revealing the molecular, biochemical and biological mechanisms that underlie the processes of ageing and development in various species as well as of age-associated diseases. Emphasis is placed on investigations that delineate the contribution of macromolecular damage and cytotoxicity, genetic programs, epigenetics and genetic instability, mitochondrial function, alterations of metabolism and innovative anti-aging approaches. For all of the mentioned studies it is necessary to address the underlying mechanisms. Purely descriptive or correlative or case studies as well as various -omics data not linked to functional analyses are not considered.Mechanisms of Ageing and Development publishes original research, review and mini-review articles. Authors should denote in the cover letter how their research is linked with previously published work. Review and mini-review articles are considered from authors having a documented experience and a strong publication record in the given field. The journal also publishes Special Issues that focus on emerging research areas. Special Issues may include all types of articles following peer review. Proposals should be sent directly to the Editor-in-Chief.

From the journal's Aims & Scope

Research area (LetPub): Geriatrics & Gerontology

Editor-in-chief Efstathios GonosPublisher website

Editorial board by country: 6 in mainland China (about 9%); most named United States 17, Germany 11, Italy 9, Mainland China 6, Greece 6 (69 members with a country) Editorial board ↗Publisher website ·

Main research topics OpenAlex counts of recent articles; shares are approximate

  1. Genetics, Aging, and Longevity in Model OrganismsBiochemistry, Genetics and Molecular Biology14.6%
  2. Telomeres, Telomerase, and SenescenceMedicine8.6%
  3. Mitochondrial Function and PathologyBiochemistry, Genetics and Molecular Biology6.8%
  4. Adipose Tissue and MetabolismMedicine6.7%
  5. DNA Repair MechanismsBiochemistry, Genetics and Molecular Biology6.1%
  6. T-cell and B-cell ImmunologyImmunology and Microbiology4.7%
  7. Immune Cell Function and InteractionImmunology and Microbiology4.4%
  8. Diverse Scientific and Economic StudiesEconomics, Econometrics and Finance3.6%

Rankings & indexing

CAS ranking and database indexing

CAS Journal Ranking

CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 2
LevelCategoryZone
MajorMedicineZone 2
MinorGeriatrics & GerontologyZone 2
MinorCell BiologyZone 3

Top journal: noReview journal: no

CAS Xinrui Journal Ranking (March 2026)Medicine Zone 2
LevelCategoryZone
MajorMedicineZone 2
MinorCell BiologyZone 2
MinorGeriatrics & GerontologyZone 2

Top journal: noReview journal: not marked

CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 3
LevelCategoryZone
MajorMedicineZone 3
MinorCell BiologyZone 3
MinorGeriatrics & GerontologyZone 3

Top journal: noReview journal: no

Database indexing

SCIEScopusLetPub

International journal early-warning lists: not listed in any editionLetPub

Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.

Metrics

Impact metrics and publication volume

Impact

Impact factor
6.45LetPub ·
Impact factor (publisher)
6.5Publisher website ·
CiteScore 2026-06
10.1LetPub ·
CiteScore (publisher)
10.1Publisher website ·
SJR 2026-06
1.9LetPub ·
SNIP 2026-06
1.31LetPub ·
h-index
107LetPub ·
h-index
173OpenAlex ·
i10-index
4,112OpenAlex ·
2-year mean citedness
4.88OpenAlex ·
Self-citation rate
1.5%LetPub ·
Share of gold OA articles
40.18%LetPub ·

Volume

Articles per year
73LetPub ·

Articles by year OpenAlex count · 6,168 in total · the current year is incomplete

YearArticlesOpen accessCitations
2026803643
20258651338
20248140824
202382441,777
202289401,931
2021131624,624

Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.

Review & acceptance

Review time and acceptance

Review time from article dates manuscript dates registered with PubMed · to

89 daysMedian, submission to acceptance · P25–P75 62 days – 123 days

Acceptance to online
median 2 days (103 articles)
Submission to online
median 91 days
Sample
103 articles with submission and acceptance dates (185 in the window); the latest was accepted on

Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".

Other sources

Average review time (community reports)
6–12 weeksLetPub ·
Average acceptance (community reports)
ModerateLetPub ·
Submission to first decision
1 daysPublisher website ·
First decision after review
41 daysPublisher website ·
Submission to acceptance
77 daysPublisher website ·
Acceptance to publication
2 daysPublisher website ·
Peer review
Single anonymous peer reviewPublisher website

Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.

Fees & open access

APC and open-access policy

Hybrid open accessLetPub

A subscription journal in which authors can pay to publish their article open access.

SourceAPCFee waiverLicenseObserved
OpenAlexUSD 4,780 / EUR 4,470 / GBP 3,830 / JPY 592,860——
Publisher websiteUSD 4,850——

A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.

The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.

Submission

Article types and submission policies (journal website)

What to prepare7 items from the author guidelines
Abstract
≤ 250 words
Keywords
1–7
Manuscript length
≤ 1,000 words
Reference style
Author–date
Highlights
Required
Graphical abstract
Optional
Cover letter
Required
Publisher website · model-extracted, each line checked against the text
Article types accepted11
  1. advances in ageingThere is also an "Advances in Ageing" section, where meeting reports, opinions or other contributions to elucidate recent developments in the field are publishe…Length not stated
  2. opinionResearch papers, including a Summary of 100-200 words, usually subdivided into sections, e.g. Introduction, Materials and Methods, Results and Discussion.Short …Length not stated
  3. opinion papersOpinion Papers are meant to stimulate discussion on selected topics that are of great interest to the science of ageing. Their format consists of a short challe…Length not stated
  4. progress papersProgress Papers illuminating a novel development with potentially high relevance to the science of ageing, are also usually solicited but can be submitted after…Length not stated
  5. regular articleResearch papers, including a Summary of 100-200 words, usually subdivided into sections, e.g. Introduction, Materials and Methods, Results and Discussion.Short …Length not stated
  6. research paperResearch papers, including a Summary of 100-200 words, usually subdivided into sections, e.g. Introduction, Materials and Methods, Results and Discussion.Short …Length not stated
  7. research papersResearch papers, including a Summary of 100-200 words, usually subdivided into sections, e.g. Introduction, Materials and Methods, Results and Discussion.Length not stated
  8. reviewResearch papers, including a Summary of 100-200 words, usually subdivided into sections, e.g. Introduction, Materials and Methods, Results and Discussion.Short …Length not stated
  9. review articleResearch papers, including a Summary of 100-200 words, usually subdivided into sections, e.g. Introduction, Materials and Methods, Results and Discussion.Short …Length not stated
  10. reviews or mini-reviewsReviews or mini-reviews on existing topics in the science of ageing are encouraged. In addition to normal submissions, the editors also commission review articl…Length not stated
  11. short communicationResearch papers, including a Summary of 100-200 words, usually subdivided into sections, e.g. Introduction, Materials and Methods, Results and Discussion.Short …Length not stated
Publisher website
Policy excerpts from the journal's websiteAI use, Authorship, Conflicts of interest, Publication ethics, License & copyright, Open access, Peer review, Preprints
AI use Declaration of generative AI use

Authors must declare the use of generative AI tools in the manuscript preparation process upon submission of the paper.Generative AI and AI-assisted technologies (“AI tools”) have been rapidly adopted in research and scholarly publishing, offering significant benefits while requiring clear standards for responsible and transparent use.Authors preparing a manuscript for this journal may use AI tool…

Source ↗Publisher website ·
Authorship Group authorship

Group authorship refers to the attribution of an article to a defined and named group of authors whose members have contributed to the work. Examples include research consortia, clinical trial groups, collaborative networks, task forces or working groups, expert panels or consensus groups, and participatory research groups. Group authorship must be declared on the title page at submission. When av…

Source ↗Publisher website ·
Conflicts of interest Declaration of competing interests

All authors must disclose any financial and personal relationships with other people or organizations that could inappropriately influence or bias their work. Examples of potential competing interests include:EmploymentConsultanciesStock ownershipHonorariaPaid expert testimonyPatent applications or registrationsGrants or any other fundingAffiliation with the journal as an Editor or Advisory Board …

Source ↗Publisher website ·
Publication ethics

Publishing ethics policy Model summary

Authors must follow ethical guidelines stated in Elsevier's Publishing Ethics Policy.

Source ↗Publisher website ·
License & copyright License options

Authors will be offered open access user license options which will determine how you, and third parties, can reuse your open access article. We advise that you review these options and any funding body license requirements before selecting a license option.

Source ↗Publisher website ·
Open access Open access

We refer you to our open access information page to learn about open access options for this journal.

Source ↗Publisher website ·
Peer review Peer review

Single anonymized review process Model summary

This journal follows a single anonymized review process. Your submission will initially be assessed by our editors. If your submission is deemed suitable, it will typically be sent to be reviewed by a minimum of two reviewers for an independent expert assessment of the scientific quality. The decision as to whether your article is accepted or rejected for publication will be made by our editors.Re…

Source ↗Publisher website ·
Preprints Preprints

Preprint sharing allowed Model summary

Preprint sharingAuthors may share preprints in line with Elsevier's article sharing policy. Sharing preprints, such as on a preprint server, will not count as prior publication.We advise you to read our policy on multiple, redundant or concurrent publication.

Source ↗Publisher website ·

Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.

Profile

Publication details and official links

Publisher
Elsevier Ireland Ltd
Country or region
SWITZERLAND
Language
English
Frequency
Monthly
Founded
1972
ISSN
0047-6374
Electronic ISSN
1872-6216
Official links

FAQ

Frequently asked questions about Mechanisms of Ageing and Development

What CAS zone is Mechanisms of Ageing and Development in?

In the 2025 upgraded edition of the CAS Journal Ranking, Mechanisms of Ageing and Development is in Zone 2 of Medicine, and in Zone 2 of the minor category Geriatrics & Gerontology / Cell Biology. In the 2026 Xinrui edition it is in Zone 2 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.

What is the impact factor of Mechanisms of Ageing and Development?

The latest impact factor listed by LetPub is 6.45; CiteScore 10.1, h-index 173.

How long does peer review take at Mechanisms of Ageing and Development?

Based on the dates recorded on 103 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 89 days (interquartile range 62–123 days); authors report an average review time of 6–12 weeks; the community-reported acceptance is “Moderate”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.

What are the manuscript requirements of Mechanisms of Ageing and Development?

According to the journal's author guidelines: Abstract: ≤ 250 words; Keywords: 1–7; Manuscript length: ≤ 1,000 words; Reference style: Author–date; Highlights: Required; Graphical abstract: Optional; Cover letter: Required. A model extracted these from the author guidelines and each was checked against the text; check the latest version on the journal's website before submitting.

Where are the editorial board members of Mechanisms of Ageing and Development based?

Of the 69 board members whose country the journal's board page names, 6 (about 9%) are in mainland China; the countries named most often are United States (17), Germany (11) and Italy (9). Counted from the institutions listed on the board page; for reference only.

Which databases index Mechanisms of Ageing and Development?

According to LetPub and DOAJ records, Mechanisms of Ageing and Development is indexed in SCIE and Scopus.

Is Mechanisms of Ageing and Development open access, and what is the APC?

Mechanisms of Ageing and Development is a hybrid journal. For open-access publication: APC about USD 4,780.

Sources and updates

The facts on this page come from LetPub, Publisher website, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-30). Last updated: .