Journal profile · Immunology
Journal of Clinical Immunology
ISSN 0271-9142 · eISSN 1573-2592 · Springer US · UNITED STATES · Bimonthly · Founded 1981
Journal of Clinical Immunology: CAS Zone 2 · Medicine (2025 upgraded edition); impact factor 4.11; hybrid open access; APC about USD 4,990; median 211 days to acceptance (78 articles, last 24 months); community-reported acceptance: about 50%; 120 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
Journal of Clinical Immunology is published by Springer US and is in Zone 2 of Medicine in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Immunodeficiency and Autoimmune Disorders, Immune Cell Function and Interaction and T-cell and B-cell Immunology, together about 44.4% of its articles. Its main subfields are Immunology. (generated from OpenAlex topic counts and CAS ranking data)
The Journal of Clinical Immunology publishes high impact papers in the area of human immunology that explore the diagnosis, pathogenesis, prognosis, or treatment of human diseases. The Journal is particularly focused on primary immunodeficiencies and related diseases. These include inborn errors of immunity, in the broad sense of the term, their underlying genotypes and their diverse phenotypes, including infection, malignancy, allergy, auto-inflammation, and autoimmunity. We consider a wide range of studies in this area, ranging from genetic discovery, clinical description, immunologic assessment, diagnostic approach, prognosis evaluation, and treatment intervention. Case reports are considered if they are truly original and are accompanied by a succinct review of the relevant medical literature and how the novel case study advances the field. The four categories of papers are detailed in the instructions to authors.
From the journal's Aims & Scope
Research area (LetPub): Immunology
Editor-in-chief Vincent BonaguraPublisher website
Editorial board by country: 2 in mainland China (about 2%); most named United States 21, Spain 6, United Kingdom 5, India 4, France 4 (90 members with a country) Editorial board ↗Publisher website ·
Main research topics OpenAlex counts of recent articles; shares are approximate
- Immunodeficiency and Autoimmune DisordersImmunology and Microbiology24.9%
- Immune Cell Function and InteractionImmunology and Microbiology10.2%
- T-cell and B-cell ImmunologyImmunology and Microbiology9.3%
- Blood disorders and treatmentsBiochemistry, Genetics and Molecular Biology6.1%
- Monoclonal and Polyclonal Antibodies ResearchMedicine4.1%
- Platelet Disorders and TreatmentsMedicine3.7%
- Immune Response and InflammationImmunology and Microbiology3.2%
- Immunotherapy and Immune ResponsesImmunology and Microbiology3%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 2 |
| Minor | Immunology | Zone 2 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Medicine Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 2 |
| Minor | Immunology | Zone 2 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 2 |
| Minor | Immunology | Zone 2 |
Top journal: noReview journal: no
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Indexing the journal's website claims
MEDLINEPubMedEmbaseCASCAB AbstractsCurrent ContentsPublisher website
Other: Google Scholar, EBSCO, ProQuest, Dimensions, CNKI, Baidu, AGRICOLA, Naver, OCLC, Portico, CLOCKSS
As the journal's website lists them, not checked against each database; for Web of Science editions the records above apply.
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 4.11LetPub ·
- Impact factor (publisher) 2025
- 4.1Publisher website ·
- 5-year impact factor (publisher) 2025
- 5.1Publisher website ·
- CiteScore 2026-06
- 10.1LetPub ·
- SJR 2026-06
- 1.8LetPub ·
- SNIP 2026-06
- 1.76LetPub ·
- h-index
- 87LetPub ·
- h-index
- 147OpenAlex ·
- i10-index
- 2,898OpenAlex ·
- 2-year mean citedness
- 3.89OpenAlex ·
- Self-citation rate
- 4.9%LetPub ·
- Share of gold OA articles
- 62.47%LetPub ·
Volume
- Articles per year
- 92LetPub ·
- Downloads per year (publisher) 2025
- 1,100,000Publisher website ·
Articles by year OpenAlex count · 4,666 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 100 | 100 | 33 |
| 2025 | 120 | 120 | 304 |
| 2024 | 212 | 143 | 1,345 |
| 2023 | 219 | 139 | 2,087 |
| 2022 | 236 | 139 | 4,719 |
| 2021 | 263 | 169 | 5,440 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with Crossref · to
211 daysMedian, submission to acceptance · P25–P75 128 days – 275 days
- Acceptance to online
- median 25 days (78 articles)
- Submission to online
- median 240 days
- Sample
- 78 articles with submission and acceptance dates (161 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Average review time (community reports)
- about 2 monthsLetPub ·
- Average acceptance (community reports)
- 50%LetPub ·
- Submission to first decision
- 17 daysPublisher website ·
- Peer review
- Single anonymous peer review, Double anonymous peer reviewPublisher website
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Hybrid open accessLetPub
A subscription journal in which authors can pay to publish their article open access.
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| OpenAlex | USD 4,990 / EUR 3,890 / GBP 3,390 | — | — | |
| Publisher website | Yes, amount not published | — | — |
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
What to prepare6 items from the author guidelines
- Abstract
- 150–250 words
- Keywords
- ≥ 4
- Manuscript length
- ≤ 1,200 words
- Reference style
- Numbered, in order of citation
- Suggested reviewers
- Optional
- Cover letter
- Required
Article types accepted12, with length limits
- case reportThe Journal of Clinical Immunology publishes the following types of articles: 1. Letters to the Editor 2. Original Articles 3. CME Review Articles 4. “How I Man…Length not stated
- cme review articles3. CME Review ArticlesLength not stated
- commentaryThe Journal of Clinical Immunology publishes the following types of articles: 1. Letters to the Editor 2. Original Articles 3. CME Review Articles 4. “How I Man…Length not stated
- editorialThe Journal of Clinical Immunology publishes the following types of articles: 1. Letters to the Editor 2. Original Articles 3. CME Review Articles 4. “How I Man…Length not stated
- letterThe Journal of Clinical Immunology publishes the following types of articles: 1. Letters to the Editor 2. Original Articles 3. CME Review Articles 4. “How I Man…main text ≤ 1,200 words
- letter to the editorThe Journal of Clinical Immunology publishes the following types of articles: 1. Letters to the Editor 2. Original Articles 3. CME Review Articles 4. “How I Man…Length not stated
- letters to the editorThe Journal of Clinical Immunology publishes the following types of articles: 1. Letters to the Editor 2. Original Articles 3. CME Review Articles 4. “How I Man…Length not stated
- original articleThe Journal of Clinical Immunology publishes the following types of articles: 1. Letters to the Editor 2. Original Articles 3. CME Review Articles 4. “How I Man…Length not stated
- original articles2. Original ArticlesLength not stated
- regular articleends • Figures The maximum length for a Regular Article is 4,000 words of text - not including the abstract, tables, figure legendmain text ≤ 4,000 words
- review articleThe Journal of Clinical Immunology publishes the following types of articles: 1. Letters to the Editor 2. Original Articles 3. CME Review Articles 4. “How I Man…Length not stated
- “how i manage” articles4. “How I Manage” ArticlesLength not stated
Policy excerpts from the journal's websiteAI use, Authorship, Conflicts of interest, Data availability, Publication ethics, License & copyright, Open access, Peer review, Trial registration / reporting guidelines
- AI use Generative AI Images
Please check Springer’s policy on generative AI images and make sure your work adheres to the principles described therein. Back to top
Source ↗Publisher website ·- Authorship Authorship principles
Manuscript submission requirements Model summary
These guidelines describe authorship principles and good authorship practices to which prospective authors should adhere to. Authorship clarified The Journal and Publisher assume all authors agreed with the content and that all gave explicit consent to submit and that they obtained consent from the responsible authorities at the institute/organization where the work has been carried out, before th…
Source ↗Publisher website ·- Conflicts of interest Disclosures and declarations
All authors are requested to include information regarding sources of funding, financial or non-financial interests, study-specific approval by the appropriate ethics committee for research involving humans and/or animals, informed consent if the research involved human participants, and a statement on welfare of animals if the research involved animals (as appropriate). The decision whether such …
Source ↗Publisher website ·- Data availability Data Availability
Data availability statement Model summary
This journal encourages authors to provide an optional statement of data availability in their article. Data Availability Statements should include information on where data supporting the results reported in the article can be found, including, where applicable, hyperlinks to publicly archived datasets analysed or generated during the study. Data availability statements can also indicate whether …
Source ↗Publisher website ·- Publication ethics Compliance with Ethical Standards
Ethics approval Model summary
To ensure objectivity and transparency in research and to ensure that accepted principles of ethical and professional conduct have been followed, authors should include information regarding sources of funding, potential conflicts of interest (financial or non-financial), informed consent if the research involved human participants, and a statement on welfare of animals if the research involved an…
Source ↗Publisher website ·- License & copyright
Permissions Model summary
Authors wishing to include figures, tables, or text passages that have already been published elsewhere are required to obtain permission from the copyright owner(s) for both the print and online format and to include evidence that such permission has been granted when submitting their papers.
Source ↗Publisher website ·- Open access Open access publishing
To find out more about publishing your work Open Access in Journal of Clinical Immunology, including information on fees, funding and licences, visit our Open access publishing page. Back to top
Source ↗Publisher website ·- Peer review Single-blind peer review
Single-blind peer review Model summary
This journal follows a single-blind reviewing procedure. This journal also publishes special/guest-edited issues. The peer review process for these articles is the same as the peer review process of the journal in general. Additionally, if a guest editor authors an article in their issue/collection, they will not handle the peer review process.
Source ↗Publisher website ·- Trial registration / reporting guidelines Clinical Trial Registration
The World Health Organization (WHO) definition of a clinical trial is "any research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes". The WHO defines health interventions as “A health intervention is an act performed for, with or on behalf of a person or population whose purpose is to ass…
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- Springer US
- Country or region
- UNITED STATES
- Language
- English
- Frequency
- Bimonthly
- Founded
- 1981
- ISSN
- 0271-9142
- Electronic ISSN
- 1573-2592
- Official links
- Journal homepage ↗OpenAlex
- Submission system ↗Publisher website
- Author guidelines ↗LetPub
FAQ
Frequently asked questions about Journal of Clinical Immunology
What CAS zone is Journal of Clinical Immunology in?
In the 2025 upgraded edition of the CAS Journal Ranking, Journal of Clinical Immunology is in Zone 2 of Medicine, and in Zone 2 of the minor category Immunology. In the 2026 Xinrui edition it is in Zone 2 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Journal of Clinical Immunology?
The latest impact factor listed by LetPub is 4.11; CiteScore 10.1, h-index 147.
How long does peer review take at Journal of Clinical Immunology?
Based on the dates recorded on 78 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 211 days (interquartile range 128–275 days); authors report an average review time of about 2 months; the community-reported acceptance is “about 50%”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
What are the manuscript requirements of Journal of Clinical Immunology?
According to the journal's author guidelines: Abstract: 150–250 words; Keywords: ≥ 4; Manuscript length: ≤ 1,200 words; Reference style: Numbered, in order of citation; Suggested reviewers: Optional; Cover letter: Required. A model extracted these from the author guidelines and each was checked against the text; check the latest version on the journal's website before submitting.
Where are the editorial board members of Journal of Clinical Immunology based?
Of the 90 board members whose country the journal's board page names, 2 (about 2%) are in mainland China; the countries named most often are United States (21), Spain (6) and United Kingdom (5). Counted from the institutions listed on the board page; for reference only.
Which databases index Journal of Clinical Immunology?
According to LetPub and DOAJ records, Journal of Clinical Immunology is indexed in SCIE and Scopus. The journal's website also lists MEDLINE, PubMed, Embase, CAS, CAB Abstracts and Current Contents; that list has not been checked against each database.
Is Journal of Clinical Immunology open access, and what is the APC?
Journal of Clinical Immunology is a hybrid journal. For open-access publication: APC about USD 4,990.
Sources and updates
The facts on this page come from LetPub, OpenAlex, Publisher website; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-24). Last updated: .