Journal profile · Toxicology
International Journal of Toxicology
ISSN 1091-5818 · eISSN 1092-874X · SAGE Publications Inc. · UNITED STATES · Bimonthly · Founded 1997
International Journal of Toxicology: CAS Zone 4 · Medicine (2025 upgraded edition); impact factor 1.31; hybrid open access; APC about USD 4,150; review about 59 days (submission to acceptance, publisher); community-reported acceptance: about 25%; 75 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
International Journal of Toxicology is published by SAGE Publications Inc. and is in Zone 4 of Medicine in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Effects and risks of endocrine disrupting chemicals, Carcinogens and Genotoxicity Assessment and Animal testing and alternatives, together about 40.3% of its articles. (generated from OpenAlex topic counts and CAS ranking data)
International Journal of Toxicology (IJT) offers academic, industry, and regulatory toxicologists, as well as toxicology consultants, timely, peer-reviewed, multidisciplinary articles and incisive reviews on contemporary issues in toxicology, plus safety assessments, novel approaches to toxicological testing, mechanisms of toxicity, biomarkers, and risk assessment. Each issue of IJT provides an important forum for articles that promote basic toxicology research, as well as those that facilitate and improve toxicology practice.We are currently seeking manuscript submissions in these (and related) areas:• Advances in drug development• Safety assessments• New therapeutic targets• Alternatives/refinement to use of animals in toxicology• Target organ toxicology• Immunotoxicology testing advances/challenges• Regulatory issues• New approaches to toxicological testingand data interpretation• Risk assessment advances• Biomarkers of toxicity• Mechanisms of toxicology• Virtual control groupsInternational Journal of Toxicology is seeking papers on the topic of virtual control groups. Are you or your company implementing virtual control groups? Have you performed any analyses of feasibility for endpoints related to histopathology, clinical chemistry, or other nonclinical toxicology endpoints? What statistical considerations are required?IJT also publishes invited reviews, articles based on symposia, book and media reviews, and editorials. IJT publishes sponsored supplemental issues, including four issues each year devoted to contributions from the Cosmetic Ingredient Review Expert Panel.International Journal of Toxicology, the official journal of the American College of Toxicology (ACT), welcomes contributions from authors, reviewers, and Editorial Board members from all backgrounds, and supports aspiring and established toxicology professionals. ACT is committed to diversity, equity, and inclusion (DEI) within our organization. We strive to empower individuals to actively engage, collaborate, and exchange ideas, and we embrace diversity in expression, perspective, and experience.Submit your manuscript today at https://mc.manuscriptcentral.com/uito
From the journal's Aims & Scope
Research area (LetPub): Toxicology
Editorial board by country: 1 in mainland China (about 2%); most named United States 41, Mainland China 1, United Kingdom 1, India 1, Belgium 1 (45 members with a country) Editorial board ↗Publisher website ·
Main research topics OpenAlex counts of recent articles; shares are approximate
- Effects and risks of endocrine disrupting chemicalsEnvironmental Science16.1%
- Carcinogens and Genotoxicity AssessmentBiochemistry, Genetics and Molecular Biology14.3%
- Animal testing and alternativesVeterinary10%
- Pesticide Exposure and ToxicityAgricultural and Biological Sciences9.8%
- Contact Dermatitis and AllergiesMedicine9.2%
- Immunotoxicology and immune responsesImmunology and Microbiology6%
- Toxic Organic Pollutants ImpactEnvironmental Science4%
- Computational Drug Discovery MethodsComputer Science2.2%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 4 |
| Minor | Pharmacology & Pharmacy | Zone 4 |
| Minor | Toxicology | Zone 4 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Medicine Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 4 |
| Minor | Pharmacology & Pharmacy | Zone 4 |
| Minor | Toxicology | Zone 4 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 4 |
| Minor | Pharmacology & Pharmacy | Zone 4 |
| Minor | Toxicology | Zone 4 |
Top journal: noReview journal: no
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 1.31LetPub ·
- Impact factor (publisher)
- 1.3Publisher website ·
- 5-year impact factor (publisher)
- 2Publisher website ·
- CiteScore 2026-06
- 2.5LetPub ·
- SJR 2026-06
- 0.4LetPub ·
- SNIP 2026-06
- 0.55LetPub ·
- h-index
- 51LetPub ·
- h-index
- 87OpenAlex ·
- i10-index
- 1,033OpenAlex ·
- 2-year mean citedness
- 1.63OpenAlex ·
- Self-citation rate
- 0%LetPub ·
- Share of gold OA articles
- 9.31%LetPub ·
Volume
- Articles per year
- 66LetPub ·
- Articles per year (publisher)
- 3Publisher website ·
Articles by year OpenAlex count · 2,458 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 57 | 15 | 4 |
| 2025 | 75 | 26 | 103 |
| 2024 | 55 | 38 | 197 |
| 2023 | 103 | 67 | 312 |
| 2022 | 67 | 11 | 494 |
| 2021 | 60 | 18 | 459 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Publisher-reported review time from the journal's website
59 dayssubmission to acceptance · community reports about 4.5 months
The publisher's own definition applies; dates from this journal's articles in the last 24 months are not available yet, so the publisher's figure is used.
Figures by source
- Average review time (community reports)
- about 4.5 monthsLetPub ·
- Average acceptance (community reports)
- 25%LetPub ·
- Acceptance rate (publisher)
- 11.4%Publisher website ·
- Submission to first decision
- 1 daysPublisher website ·
- Submission to acceptance
- 59 daysPublisher website ·
- Acceptance to publication
- 30 daysPublisher website ·
- Peer review
- Single anonymous peer reviewPublisher website
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
A subscription journal in which authors can pay to publish their article open access.
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| OpenAlex | USD 4,150 / GBP 3,043 | — | — | |
| Publisher website | Yes, amount not published | — | — |
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
Article types accepted4
- case reportPlease visit the Sage Journal Author Gateway for guidance on producing visual and/or video abstracts. International Journal of Toxicology (the Journal) is the o…Length not stated
- case studyPlease visit the Sage Journal Author Gateway for guidance on producing visual and/or video abstracts. International Journal of Toxicology (the Journal) is the o…Length not stated
- original research paperPlease visit the Sage Journal Author Gateway for guidance on producing visual and/or video abstracts. International Journal of Toxicology (the Journal) is the o…Length not stated
- reviewPlease visit the Sage Journal Author Gateway for guidance on producing visual and/or video abstracts. International Journal of Toxicology (the Journal) is the o…Length not stated
Policy excerpts from the journal's websiteAuthorship, Data availability, Publication ethics, Open access, Peer review, Plagiarism, Preprints, Trial registration / reporting guidelines
- Authorship Authorship
Please view our authorship policies, which includes information on criteria for authorship, who should be the corresponding author and more. Please note that AI chatbots, for example ChatGPT, should not be listed as authors. For more information see the policy on Use of ChatGPT and generative AI tools.
Source ↗Publisher website ·- Data availability Data availability
The Journal is committed to facilitating openness, transparency and reproducibility of research, and has the following research data sharing policy. For more information, including FAQs please visit the Sage Research Data policy pages. Subject to appropriate ethical and legal considerations, authors are encouraged to: Share your research data in a relevant public data repository Include a data ava…
Source ↗Publisher website ·- Publication ethics Ethical considerations
Please include your ethics approval statements under this heading, even if you have already included ethics approval information in your methods section. If ethical approval was not required, you need to explicitly state this. All papers reporting studies involving human participants, human data or human tissue must state that the relevant Ethics Committee or Institutional Review Board approved th…
Source ↗Publisher website ·- Open access Publishing fees and open access
There are no fees payable to submit or publish in this journal. Figures submitted in color will be published in color in the online version of the journal at no cost. If you wish to have color figures in the printed version, the first image is $800 and any subsequent images in the same contribution cost $200. Optional open access publishing is available for a fee via the Sage Choice program, and O…
Source ↗Publisher website ·- Peer review Peer review policy
Single anonymized review Model summary
The following summary describes the peer review process for this journal: Identity transparency: Single-anonymized Reviewer interacts with: Editor Review information published: None Your manuscript will undergo an initial evaluation. If it does not conform to the requirements laid out in these guidelines, it will be returned to you for amendments prior to peer review. Manuscripts may be desk rejec…
Source ↗Publisher website ·- Plagiarism Plagiarism
The journal and Sage take issues of copyright infringement, plagiarism or other breaches of best practice in publication very seriously. Please read Sage's complete policy on plagiarism and the actions we may take.
Source ↗Publisher website ·- Preprints Preprints
The journal will consider submissions of manuscripts that have been posted on preprint servers. Please enter the preprint DOI in the designated field when submitting your manuscript. We advise that you inform the Journal Editorial office about your posted preprint at submission. Note that you should not post an updated version of your manuscript on a preprint server while it is being peer reviewed…
Source ↗Publisher website ·- Trial registration / reporting guidelines Clinical trial registration
The journal conforms to the ICMJE requirement that clinical trials are registered in a WHO-approved public trials registry at or before the time of first participant enrollment as a condition of consideration for publication. The trial registry name and URL, and registration number must be included at the end of the abstract.
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- SAGE Publications Inc.
- Country or region
- UNITED STATES
- Language
- English
- Frequency
- Bimonthly
- Founded
- 1997
- ISSN
- 1091-5818
- Electronic ISSN
- 1092-874X
- Official links
- Journal homepage ↗OpenAlex
- Submission system ↗Publisher website
- Special issues ↗Publisher website
FAQ
Frequently asked questions about International Journal of Toxicology
What CAS zone is International Journal of Toxicology in?
In the 2025 upgraded edition of the CAS Journal Ranking, International Journal of Toxicology is in Zone 4 of Medicine, and in Zone 4 of the minor category Pharmacology & Pharmacy / Toxicology. In the 2026 Xinrui edition it is in Zone 4 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of International Journal of Toxicology?
The latest impact factor listed by LetPub is 1.31; CiteScore 2.5, h-index 87.
How long does peer review take at International Journal of Toxicology?
The publisher reports about 59 days (submission to acceptance); authors report an average review time of about 4.5 months; the community-reported acceptance is “about 25%”; the journal's website gives an acceptance rate of 11.4%. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
Where are the editorial board members of International Journal of Toxicology based?
Of the 45 board members whose country the journal's board page names, 1 (about 2%) are in mainland China; the countries named most often are United States (41), Mainland China (1) and United Kingdom (1). Counted from the institutions listed on the board page; for reference only.
Which databases index International Journal of Toxicology?
According to LetPub and DOAJ records, International Journal of Toxicology is indexed in SCIE and Scopus.
Is International Journal of Toxicology open access, and what is the APC?
International Journal of Toxicology is a hybrid journal. For open-access publication: APC about USD 4,150.
Sources and updates
The facts on this page come from LetPub, Publisher website, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-24). Last updated: .