Journal profile · Multiple
In vitro models
ISSN 2731-3433 · eISSN 2731-3441
In vitro models: CAS Zone 4 · Biology (2026 Xinrui edition); impact factor 3 (journal website); hybrid open access; APC about USD 2,490; median 96 days to acceptance (76 articles, last 24 months); 22 articles in 2025; indexed in ESCI.
Scope
Aims, scope and focus
In vitro models is classed under Biology in the CAS Journal Ranking. By OpenAlex counts of its recent articles, its largest topics are 3D Printing in Biomedical Research, Cancer Cells and Metastasis and Tissue Engineering and Regenerative Medicine, together about 39.5% of its articles. Its main subfields are Biomedical Engineering. (generated from OpenAlex topic counts and CAS ranking data)
In vitro models aims to become a leading journal among the top multidisciplinary journals covering all aspects of in vitro models research, which also includes a broad spectrum of topics related to at the interface of biomaterials science, chemistry, physics, engineering, informatics, nanotechnology, pharma, medicine, and biology. The new journal provides a specialized forum for the publication of significant and original work related to experimental and theoretical studies on fundamental and applied inter- and multidisciplinary research dealing with in vitro models, and in particular focusing on 3D cell/tissue culture and enabling technologies. In vitro models will publish peer-reviewed Communications, Reviews, Concepts, Highlights, Essays/Editorials, and full original Research Articles on all aspects of in vitro models research, including, but not limited to, the following topics: In vitro models New Perspectives in in vitro tissue models Research Complementary and Alternative models to animal experimentation Cell culturing Methods (e.g. 2D and 3D cell culture) Ex vivo models Biomaterials as extracellular matrix Drug development Bio 3D printing Cell engineering Dynamic culturing Microfluidics Biofluid mechanics Organ-on-a-chip Bioreactors In silico models Modelling and simulation Nanomedicine Tissue engineering Precision Medicine Cancer research Regenerative Medicine Translational Research
From the journal's Aims & Scope
Research area (LetPub): Multiple
Editor-in-chief Joaquim MiguelPublisher website
Editorial board by country: 3 in mainland China (about 4%); most named United States 14, India 6, United Kingdom 5, Italy 5, Portugal 5 (73 members with a country) Editorial board ↗Publisher website ·
Main research topics OpenAlex counts of recent articles; shares are approximate
- 3D Printing in Biomedical ResearchEngineering21.4%
- Cancer Cells and MetastasisMedicine11.8%
- Tissue Engineering and Regenerative MedicineMedicine6.4%
- Bone Tissue Engineering MaterialsEngineering5.5%
- Cellular Mechanics and InteractionsBiochemistry, Genetics and Molecular Biology5%
- Pluripotent Stem Cells ResearchBiochemistry, Genetics and Molecular Biology4.1%
- Graphene and Nanomaterials ApplicationsEngineering4.1%
- Liver physiology and pathologyMedicine3.2%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Not covered
Not covered by this edition.
CAS Xinrui Journal Ranking (March 2026)Biology Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 4 |
| Minor | Cell & Tissue Engineering | Zone 4 |
| Minor | Materials Science, Biomaterials | Zone 4 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Not covered
Not covered by this edition.
Database indexing
ESCILetPub
International journal early-warning lists: not listed in any editionLetPub
Indexing the journal's website claims
ScopusCASPublisher website
Other: Google Scholar, EBSCO, ProQuest, Dimensions, CNKI, Baidu, Naver, OCLC, Portico, CLOCKSS
As the journal's website lists them, not checked against each database; for Web of Science editions the records above apply.
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor (publisher) 2025
- 3Publisher website ·
- 5-year impact factor (publisher) 2025
- 3Publisher website ·
- h-index
- 15OpenAlex ·
- i10-index
- 26OpenAlex ·
- 2-year mean citedness
- 2.27OpenAlex ·
- Self-citation rate
- 3.3%LetPub ·
- Share of gold OA articles
- 58.93%LetPub ·
Volume
- Articles per year
- 22LetPub ·
- Downloads per year (publisher) 2025
- 90,500Publisher website ·
Articles by year OpenAlex count · 154 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 53 | 23 | 1 |
| 2025 | 22 | 20 | 92 |
| 2024 | 16 | 16 | 114 |
| 2023 | 24 | 24 | 191 |
| 2022 | 33 | 33 | 351 |
| 2021 | 6 | 6 | 49 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with Crossref · to
96 daysMedian, submission to acceptance · P25–P75 63 days – 144 days
- Acceptance to online
- median 20 days (76 articles)
- Submission to online
- median 128 days
- Sample
- 76 articles with submission and acceptance dates (76 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Submission to first decision
- 4 daysPublisher website ·
- Peer review
- Single anonymous peer review, Double anonymous peer reviewPublisher website
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Hybrid open accessLetPub
A subscription journal in which authors can pay to publish their article open access.
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| OpenAlex | USD 2,490 / EUR 3,890 | — | — |
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
Open calls for papers1, by deadline
Publisher websiteWhat to prepare4 items from the author guidelines
- Abstract
- 150–250 words
- Keywords
- ≥ 4
- Reference style
- Numbered, in order of citation
- Suggested reviewers
- Optional
Article types accepted6
- editorialOriginal Articles Authors must provide a full-length account of original research. It should be a comprehensive report of original research presenting a signifi…Length not stated
- opinionOriginal Articles Authors must provide a full-length account of original research. It should be a comprehensive report of original research presenting a signifi…Length not stated
- original articleOriginal Articles Authors must provide a full-length account of original research. It should be a comprehensive report of original research presenting a signifi…Length not stated
- original researchOriginal Articles Authors must provide a full-length account of original research. It should be a comprehensive report of original research presenting a signifi…Length not stated
- rapid communicationOriginal Articles Authors must provide a full-length account of original research. It should be a comprehensive report of original research presenting a signifi…Length not stated
- reviewOriginal Articles Authors must provide a full-length account of original research. It should be a comprehensive report of original research presenting a signifi…Length not stated
Policy excerpts from the journal's websiteAI use, Authorship, Conflicts of interest, Data availability, License & copyright, Open access, Peer review, Trial registration / reporting guidelines
- AI use Generative AI Images
Please check Springer’s policy on generative AI images and make sure your work adheres to the principles described therein. Back to top
Source ↗Publisher website ·- Authorship Authorship principles
These guidelines describe authorship principles and good authorship practices to which prospective authors should adhere to. Authorship clarified The Journal and Publisher assume all authors agreed with the content and that all gave explicit consent to submit and that they obtained consent from the responsible authorities at the institute/organization where the work has been carried out, before th…
Source ↗Publisher website ·- Conflicts of interest Competing Interests
Authors are requested to disclose interests that are directly or indirectly related to the work submitted for publication. Interests within the last 3 years of beginning the work (conducting the research and preparing the work for submission) should be reported. Interests outside the 3-year time frame must be disclosed if they could reasonably be perceived as influencing the submitted work. Disclo…
Source ↗Publisher website ·- Data availability Data availability statements
All original research must include a data availability statement. This statement should explain how to access data supporting the results and analysis in the article, including links/citations to publicly archived datasets analysed or generated during the study. Please see our full policy here. If it is not possible to share research data publicly, for instance when individual privacy could be com…
Source ↗Publisher website ·- License & copyright Copyright
Open Choice articles do not require transfer of copyright as the copyright remains with the author. In opting for open access, the author(s) agree to publish the article under a Creative Commons license. Details of the OA licences offered to authors can be found on the individual journal website, in the journal's How to publish with us guide. Back to top
Source ↗Publisher website ·- Open access Open access publishing
To find out more about publishing your work Open Access in In vitro models, including information on fees, funding and licences, visit our Open access publishing page. Back to top
Source ↗Publisher website ·- Peer review Single-blind peer review
This journal follows a single-blind reviewing procedure. This journal also publishes special/guest-edited issues. The peer review process for these articles is the same as the peer review process of the journal in general. Additionally, if a guest editor authors an article in their issue/collection, they will not handle the peer review process.
Source ↗Publisher website ·- Trial registration / reporting guidelines Clinical Trial Registration
The World Health Organization (WHO) definition of a clinical trial is "any research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes". The WHO defines health interventions as “A health intervention is an act performed for, with or on behalf of a person or population whose purpose is to ass…
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- ISSN
- 2731-3433
- Electronic ISSN
- 2731-3441
- Latest issue on the website
- Volume 5, Issue 2 (August 2026)
- Official links
- Journal homepage ↗OpenAlex
- Submission system ↗Publisher website
- Special issues ↗Publisher website
FAQ
Frequently asked questions about In vitro models
What CAS zone is In vitro models in?
In the 2026 Xinrui edition it is in Zone 4 of Biology. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of In vitro models?
The journal's website gives an impact factor of 3 (2025); this is the journal's own figure, as LetPub lists none for it; h-index 15.
How long does peer review take at In vitro models?
Based on the dates recorded on 76 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 96 days (interquartile range 63–144 days). Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
What are the manuscript requirements of In vitro models?
According to the journal's author guidelines: Abstract: 150–250 words; Keywords: ≥ 4; Reference style: Numbered, in order of citation; Suggested reviewers: Optional. A model extracted these from the author guidelines and each was checked against the text; check the latest version on the journal's website before submitting.
Where are the editorial board members of In vitro models based?
Of the 73 board members whose country the journal's board page names, 3 (about 4%) are in mainland China; the countries named most often are United States (14), India (6) and United Kingdom (5). Counted from the institutions listed on the board page; for reference only.
Which databases index In vitro models?
According to LetPub and DOAJ records, In vitro models is indexed in ESCI. The journal's website also lists Scopus and CAS; that list has not been checked against each database.
Is In vitro models open access, and what is the APC?
In vitro models is a hybrid journal. For open-access publication: APC about USD 2,490.
Sources and updates
The facts on this page come from LetPub, OpenAlex, Publisher website; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-24). Last updated: .