Journal profile · GENETICS & HEREDITY
Human Gene
ISSN 2773-0441 · Elsevier
Human Gene: CAS Zone 4 · Biology (2025 upgraded edition); impact factor 0.9 (journal website); hybrid open access; APC about USD 3,090; review about 107 days (submission to acceptance, publisher); 150 articles in 2025; indexed in ESCI and Scopus.
Scope
Aims, scope and focus
Human Gene is published by Elsevier and is in Zone 4 of Biology in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are MicroRNA in disease regulation, Cancer-related molecular mechanisms research and Circular RNAs in diseases, together about 35.2% of its articles. Its main subfields are Molecular Biology. (generated from OpenAlex topic counts and CAS ranking data)
Human Gene publishes high-quality research that advances understanding of human genes and genomes in health and disease. The journal provides a dedicated forum for studies that contribute to the discovery, characterization, and functional interpretation of human genes and genetic variation and their roles in biological mechanisms and clinically relevant phenotypes.The journal publishes original research articles, short communications, resource reports, systematic reviews, and rigorously conducted meta-analyses that integrate genetic variations with functional or mechanistic insights.Topics considered for publication span diverse areas of human molecular biology, genetics, and genomics, including but not limited toHuman genetic variation, populations, and evolution (rare/common variants, population genetics, gene–environment interactions, genetic diversity across human populations)Genetic architecture of human disease (GWAS and post-GWAS analyses; structural variants and CNV; somatic variation, including cancer; genotype–phenotype relationships)Gene regulation and genome organization (transcriptional and post-transcriptional regulation; epigenetics and chromatin biology; 3D genome architecture; RNA biology, including non-coding RNAs)Functional and mechanistic genomics (functional characterization of disease-associated variants, CRISPR and genome editing, systems genetics, experimental validation of computational predictions)Multi-omics and integrative approaches (genomic, epigenomic, transcriptomic, proteomic, and other large-scale data integration with biological or mechanistic insight)Translational and clinical genomics (variant interpretation and genomic diagnostics, pharmacogenomics, biomarker discovery and validation, genomic predictors of therapeutic response and clinical implementation)Computational and data-driven approaches in human genomics (AI and machine learning applications, predictive modeling, large-scale data integration, benchmarking)Submissions may range from studies of individual genes or variants to analyses of pathways, networks, and genome-scale datasets. Computational and data-driven studies are considered when they provide clear biological or clinical insight supported by robust validation and/or benchmarking.Studies limited to purely descriptive association analyses, methodological development without interpretative advancement, or exploratory analyses lacking biological or clinical insight are generally outside the scope of the journal.Human Gene is a companion journal to Gene and a member of the Gene Family of journals, alongside Gene Reports and Plant Gene, providing a coordinated forum for research on genes, genetic variation, and gene function, with Human Gene offering a focused platform for human-centered genomic research.
From the journal's Aims & Scope
Research area (LetPub): GENETICS & HEREDITY
Editor-in-chief Erzsebet KovesdiPublisher website
Editorial board by country: 2 in mainland China (about 4%); most named Türkiye 11, India 9, United States 4, Iran 3, Slovenia 3 (46 members with a country) Editorial board ↗Publisher website ·
Main research topics OpenAlex counts of recent articles; shares are approximate
- MicroRNA in disease regulationBiochemistry, Genetics and Molecular Biology14%
- Cancer-related molecular mechanisms researchBiochemistry, Genetics and Molecular Biology12.9%
- Circular RNAs in diseasesBiochemistry, Genetics and Molecular Biology8.2%
- RNA modifications and cancerBiochemistry, Genetics and Molecular Biology7.9%
- Ferroptosis and cancer prognosisMedicine6%
- Epigenetics and DNA MethylationBiochemistry, Genetics and Molecular Biology3.9%
- Liver Disease Diagnosis and TreatmentMedicine3.8%
- Genetics and Neurodevelopmental DisordersBiochemistry, Genetics and Molecular Biology3.6%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Biology Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 4 |
| Minor | Genetics & Heredity | Zone 4 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Biology Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 4 |
| Minor | Genetics & Heredity | Zone 4 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Not covered
Not covered by this edition.
Database indexing
ESCIScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor (publisher)
- 0.9Publisher website ·
- CiteScore 2026-06
- 1.5LetPub ·
- CiteScore (publisher)
- 1.5Publisher website ·
- SJR 2026-06
- 0.25LetPub ·
- SNIP 2026-06
- 0.26LetPub ·
- h-index
- 10OpenAlex ·
- i10-index
- 11OpenAlex ·
- 2-year mean citedness
- 1.21OpenAlex ·
- Self-citation rate
- 11.1%LetPub ·
- Share of gold OA articles
- 6.58%LetPub ·
Volume
- Articles per year
- 145LetPub ·
Articles by year OpenAlex count · 578 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 78 | 10 | 8 |
| 2025 | 150 | 11 | 134 |
| 2024 | 118 | 10 | 278 |
| 2023 | 113 | 10 | 253 |
| 2022 | 119 | 16 | 344 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Publisher-reported review time from the journal's website
107 dayssubmission to acceptance
The publisher's own definition applies; dates from this journal's articles in the last 24 months are not available yet, so the publisher's figure is used.
Figures by source
- Submission to first decision
- 5 daysPublisher website ·
- First decision after review
- 56 daysPublisher website ·
- Submission to acceptance
- 107 daysPublisher website ·
- Acceptance to publication
- 2 daysPublisher website ·
- Peer review
- Single anonymous peer reviewPublisher website
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Hybrid open accessLetPub
A subscription journal in which authors can pay to publish their article open access.
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| OpenAlex | USD 3,090 / EUR 2,890 / GBP 2,470 / JPY 383,250 | — | — |
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
What to prepare8 items from the author guidelines
- Abstract
- ≤ 250 words
- Keywords
- 1–7
- Reference style
- Vancouver
- First submission
- Free format: the journal's layout is not required
- Suggested reviewers
- Required
- Highlights
- Required
- Graphical abstract
- Required
- Cover letter
- Required
Article types accepted6
- full length articlesFull length articles Organization should be Abstract, Introduction, Materials and Methods, Results, Discussion, Acknowledgments, and References.Length not stated
- minireviewsMinireviews The journal encourages the submission of concise, highly focused review articles summarizing recent progress in very active areas of research involv…Length not stated
- reviewFull length articlesOrganization should be Abstract, Introduction, Materials and Methods, Results, Discussion, Acknowledgments, and References.MinireviewsThe jo…Length not stated
- review articleFull length articlesOrganization should be Abstract, Introduction, Materials and Methods, Results, Discussion, Acknowledgments, and References.MinireviewsThe jo…Length not stated
- short communicationFull length articlesOrganization should be Abstract, Introduction, Materials and Methods, Results, Discussion, Acknowledgments, and References.MinireviewsThe jo…Length not stated
- short communicationsShort Communications are brief papers that make a specific well-documented point. In general, a Communication should include no more than four figures and table…Length not stated
Policy excerpts from the journal's websiteAI use, Authorship, Conflicts of interest, License & copyright, Open access, Peer review, Preprints
- AI use Declaration of generative AI use
Authors must declare the use of generative AI tools in the manuscript preparation process upon submission of the paper.Generative AI and AI-assisted technologies (“AI tools”) have been rapidly adopted in research and scholarly publishing, offering significant benefits while requiring clear standards for responsible and transparent use.Authors preparing a manuscript for this journal may use AI tool…
Source ↗Publisher website ·- Authorship Group authorship
Group authorship refers to the attribution of an article to a defined and named group of authors whose members have contributed to the work. Examples include research consortia, clinical trial groups, collaborative networks, task forces or working groups, expert panels or consensus groups, and participatory research groups. Group authorship must be declared on the title page at submission. When av…
Source ↗Publisher website ·- Conflicts of interest Declaration of competing interests
All authors must disclose any financial and personal relationships with other people or organizations that could inappropriately influence or bias their work. Examples of potential competing interests include:EmploymentConsultanciesStock ownershipHonorariaPaid expert testimonyPatent applications or registrationsGrants or any other fundingAffiliation with the journal as an Editor or Advisory Board …
Source ↗Publisher website ·- License & copyright License options
Authors will be offered open access user license options which will determine how you, and third parties, can reuse your open access article. We advise that you review these options and any funding body license requirements before selecting a license option.
Source ↗Publisher website ·- Open access Open access
Open access options available Model summary
We refer you to our open access information page to learn about open access options for this journal.
Source ↗Publisher website ·- Peer review Peer review
Single anonymized review process Model summary
This journal follows a single anonymized review process. Your submission will initially be assessed by our editors. If your submission is deemed suitable, it will typically be sent to be reviewed by a minimum of two reviewers for an independent expert assessment of the scientific quality. The decision as to whether your article is accepted or rejected for publication will be made by our editors.Re…
Source ↗Publisher website ·- Preprints Preprints
Preprint sharingAuthors may share preprints in line with Elsevier's article sharing policy. Sharing preprints, such as on a preprint server, will not count as prior publication.We advise you to read our policy on multiple, redundant or concurrent publication.
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- Elsevier
- ISSN
- 2773-0441
- Official links
- Journal homepage ↗LetPub
- Submission system ↗Publisher website
- Special issues ↗Publisher website
FAQ
Frequently asked questions about Human Gene
What CAS zone is Human Gene in?
In the 2025 upgraded edition of the CAS Journal Ranking, Human Gene is in Zone 4 of Biology, and in Zone 4 of the minor category Genetics & Heredity. In the 2026 Xinrui edition it is in Zone 4 of Biology. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Human Gene?
The journal's website gives an impact factor of 0.9; this is the journal's own figure, as LetPub lists none for it; CiteScore 1.5, h-index 10.
How long does peer review take at Human Gene?
The publisher reports about 107 days (submission to acceptance). Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
What are the manuscript requirements of Human Gene?
According to the journal's author guidelines: Abstract: ≤ 250 words; Keywords: 1–7; Reference style: Vancouver; First submission: Free format: the journal's layout is not required; Suggested reviewers: Required; Highlights: Required; Graphical abstract: Required; Cover letter: Required. A model extracted these from the author guidelines and each was checked against the text; check the latest version on the journal's website before submitting.
Where are the editorial board members of Human Gene based?
Of the 46 board members whose country the journal's board page names, 2 (about 4%) are in mainland China; the countries named most often are Türkiye (11), India (9) and United States (4). Counted from the institutions listed on the board page; for reference only.
Which databases index Human Gene?
According to LetPub and DOAJ records, Human Gene is indexed in ESCI and Scopus.
Is Human Gene open access, and what is the APC?
Human Gene is a hybrid journal. For open-access publication: APC about USD 3,090.
Sources and updates
The facts on this page come from LetPub, Publisher website, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-26). Last updated: .