Journal profile · Biochemistry, Genetics and Molecular Biology-Biochemistry
Genes and Diseases
ISSN 2352-3042 · Elsevier · Netherlands
Genes and Diseases: CAS Zone 2 · Medicine (2025 upgraded edition); impact factor 14.6 (journal website); fully open access; APC about USD 2,500; median 157 days to acceptance (113 articles, last 24 months); 453 articles in 2025; indexed in Scopus.
Scope
Aims, scope and focus
Genes and Diseases is published by Elsevier and is in Zone 2 of Medicine in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are RNA modifications and cancer, Cancer-related molecular mechanisms research and Epigenetics and DNA Methylation, together about 26% of its articles. Its main subfields are Molecular Biology and Cancer Research. (generated from OpenAlex topic counts and CAS ranking data)
Genes & Diseases is a journal for molecular and translational medicine. The journal primarily focuses on publishing investigations on the molecular bases and experimental therapeutics of human diseases. Publication formats include full length research article, review article, short communication, correspondence, perspectives, commentary, views on news, and research watch.
From the journal's Aims & Scope
Research area (LetPub): Biochemistry, Genetics and Molecular Biology-Biochemistry
Editor-in-chief Ailong HuangPublisher website
Editorial board by country: 117 in mainland China (about 39%); most named United States 147, Mainland China 117, United Kingdom 6, Hong Kong, China 4, South Korea 3 (300 members with a country) Editorial board ↗Publisher website ·
Main research topics OpenAlex counts of recent articles; shares are approximate
- RNA modifications and cancerBiochemistry, Genetics and Molecular Biology11.8%
- Cancer-related molecular mechanisms researchBiochemistry, Genetics and Molecular Biology8.2%
- Epigenetics and DNA MethylationBiochemistry, Genetics and Molecular Biology6.1%
- Ferroptosis and cancer prognosisMedicine5.6%
- MicroRNA in disease regulationBiochemistry, Genetics and Molecular Biology5.4%
- Cancer, Hypoxia, and MetabolismBiochemistry, Genetics and Molecular Biology5.1%
- Circular RNAs in diseasesBiochemistry, Genetics and Molecular Biology4.9%
- Cancer-related gene regulationBiochemistry, Genetics and Molecular Biology4.5%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 2 |
| Minor | Biochemistry & Molecular Biology | Zone 2 |
| Minor | Genetics & Heredity | Zone 2 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Medicine Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 1 |
| Minor | Biochemistry & Molecular Biology | Zone 1 |
| Minor | Genetics & Heredity | Zone 1 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 2 |
| Minor | Biochemistry & Molecular Biology | Zone 2 |
| Minor | Genetics & Heredity | Zone 2 |
Top journal: noReview journal: no
Database indexing
ScopusDOAJLetPub
International journal early-warning lists: not listed in any editionLetPub
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor (publisher)
- 14.6Publisher website ·
- CiteScore 2026-06
- 10.4LetPub ·
- CiteScore (publisher)
- 10.4Publisher website ·
- SJR 2026-06
- 1.78LetPub ·
- SNIP 2026-06
- 1.44LetPub ·
- h-index
- 92OpenAlex ·
- i10-index
- 741OpenAlex ·
- 2-year mean citedness
- 2.16OpenAlex ·
- Share of gold OA articles
- 0%LetPub ·
Articles by year OpenAlex count · 2,345 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 433 | 433 | 76 |
| 2025 | 453 | 453 | 1,027 |
| 2024 | 242 | 242 | 1,336 |
| 2023 | 385 | 385 | 4,953 |
| 2022 | 268 | 268 | 7,161 |
| 2021 | 105 | 105 | 3,569 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with PubMed · to
157 daysMedian, submission to acceptance · P25–P75 103 days – 250 days
- Acceptance to online
- median 38 days (113 articles)
- Submission to online
- median 206 days
- Sample
- 113 articles with submission and acceptance dates (802 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Average review time (community reports)
- about 35 weeksLetPub ·
- Submission to final decision
- 7 daysPublisher website ·
- Submission to publication (journal-reported)
- about 50 weeksDOAJ ·
- Peer review
- Single anonymous peer reviewDOAJ
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Fully open accessDOAJ
Every article is open access; authors usually pay an article processing charge (APC).
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| DOAJ | USD 2,500 | No | CC BY, CC BY-NC-ND | |
| OpenAlex | USD 2,500 | — | — | |
| LetPub | USD 2,500 | No | — |
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
What to prepare6 items from the author guidelines
- Abstract
- ≤ 250 words
- Keywords
- 5
- Manuscript length
- ≤ 6,000 words
- Reference style
- AMA
- Suggested reviewers
- Required, 3
- Cover letter
- Required
Article types accepted7, with length limits
- commentaryCommentary is a commissioned analysis of recently published paper (published in either Genes & Diseases and/or other top-tier journals) of immediate interest.Ab…main text ≤ 1,000 words · references ≤ 1
- correspondenceCorrespondence may be accepted for publication after a fast-track editorial review. It would be comments or criticisms relevant to a paper published in Genes & …main text ≤ 1,000 words · references ≤ 1
- editorialAll manuscripts received are duly acknowledged. Upon submission, the Editorial Office will check the manuscript's conformity to technical quality and author gui…Length not stated
- letterLetters provide rapid and concise report of a novel finding that is brief in nature but is of general interest to the field. Abstract: None / Start with a salut…main text ≤ 1,200 words · references ≤ 1
- rapid communicationRapid communication documents high impact early findings that are brief in nature and with an urgent dissemination need for the scientific community. Abstract: …main text ≤ 1,200 words · references ≤ 1
- reviewArticle types include: Full Length Article Abstract: Unstructured, max of 250 wordsWord Limit: max of 6,000 words excluding abstract, references, figures and ta…Length not stated
- review articleArticle types include: Full Length Article Abstract: Unstructured, max of 250 wordsWord Limit: max of 6,000 words excluding abstract, references, figures and ta…main text ≤ 250 words · abstract ≤ 250 words · references ≤ 6
Policy excerpts from the journal's websiteAuthorship, Conflicts of interest, Publication ethics, License & copyright, Open access, Peer review, Preprints
- Authorship Author contributions
For transparency, we encourage corresponding authors to provide co-author contributions to the manuscript using the relevant CRediT roles. The CRediT taxonomy includes 14 different roles describing each contributor's specific contribution to the scholarly output. The roles are: Conceptualization; Data curation; Formal analysis; Funding acquisition; Investigation; Methodology; Project administratio…
Source ↗Publisher website ·- Conflicts of interest Declaration of interest
All authors must disclose any financial and personal relationships with other people or organizations that could inappropriately influence (bias) their work. Examples of potential competing interests include employment, consultancies, stock ownership, honoraria, paid expert testimony, patent applications/registrations, and grants or other funding. Authors must disclose any interests in two places:…
Source ↗Publisher website ·- Publication ethics Ethical Approval
For manuscripts reporting studies involving human subjects, statements identifying the committee approving the studies and confirming that informed consent was obtained from all subjects must appear in the Experimental Procedures section. All experiments on live vertebrates or higher invertebrates must be performed in accordance with relevant institutional and national guidelines and regulations. …
Source ↗Publisher website ·- License & copyright Copyright
Exclusive licensing agreement; authors retain copyright alongside scholarly usage rights; KeAi Communications Co., Ltd. granted exclusive publishing and distribution rights. Model summary
Upon acceptance of an article, authors will be asked to complete a 'Journal Publishing Agreement'. An e-mail will be sent to the corresponding author confirming receipt of the manuscript together with a 'Journal Publishing Agreement' form or a link to the online version of this agreement. Author rights For open access publishing, this journal uses an exclusive licensing agreement. Authors will ret…
Source ↗Publisher website ·- Open access Open access
Peer reviewed, open access journal with an APC paid by authors or on their behalf. Model summary
Genes & Diseases is a peer reviewed, open access journal. To provide open access, the journal has an open access fee (also known as article publishing charge, APC) paid by the authors or on their behalf (e.g. by their research funders or institution), either in the US dollar (USD $) or the Chinese currency RMB. The Article Processing Charge (APC) for the accepted manuscripts submitted on and after…
Source ↗Publisher website ·- Peer review Peer Review
This journal operates a single blind review process. All contributions will be initially assessed by the editor for suitability for the journal. Papers deemed suitable are then sent to a minimum of two independent expert reviewers to assess the scientific quality of the paper. The Editor is responsible for the final decision regarding acceptance or rejection of articles. The Editor's decision is f…
Source ↗Publisher website ·- Preprints Preprint references
Where a preprint has subsequently become available as a peer-reviewed publication, the formal publication should be used as the reference. If there are preprints that are central to your work or that cover crucial developments in the topic, but are not yet formally published, these may be referenced. Preprints should be clearly marked as such, for example by including the word preprint, or the nam…
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- Elsevier
- Country or region
- Netherlands
- Language
- English
- ISSN
- 2352-3042
- Print ISSN
- 2352-4820
- Official links
- Journal homepage ↗DOAJ
- Submission system ↗Publisher website
- Author guidelines ↗LetPub
- Aims & Scope ↗LetPub
- Special issues ↗Publisher website
- APC information ↗DOAJ
- Open access statement ↗DOAJ
- License & copyright ↗DOAJ
- Peer review process ↗LetPub
- Editorial board ↗LetPub
FAQ
Frequently asked questions about Genes and Diseases
What CAS zone is Genes and Diseases in?
In the 2025 upgraded edition of the CAS Journal Ranking, Genes and Diseases is in Zone 2 of Medicine, and in Zone 2 of the minor category Biochemistry & Molecular Biology / Genetics & Heredity. In the 2026 Xinrui edition it is in Zone 1 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Genes and Diseases?
The journal's website gives an impact factor of 14.6; this is the journal's own figure, as LetPub lists none for it; CiteScore 10.4, h-index 92.
How long does peer review take at Genes and Diseases?
Based on the dates recorded on 113 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 157 days (interquartile range 103–250 days); authors report an average review time of about 35 weeks. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
What are the manuscript requirements of Genes and Diseases?
According to the journal's author guidelines: Abstract: ≤ 250 words; Keywords: 5; Manuscript length: ≤ 6,000 words; Reference style: AMA; Suggested reviewers: Required, 3; Cover letter: Required. A model extracted these from the author guidelines and each was checked against the text; check the latest version on the journal's website before submitting.
Where are the editorial board members of Genes and Diseases based?
Of the 300 board members whose country the journal's board page names, 117 (about 39%) are in mainland China; the countries named most often are United States (147), Mainland China (117) and United Kingdom (6). Counted from the institutions listed on the board page; for reference only.
Which databases index Genes and Diseases?
According to LetPub and DOAJ records, Genes and Diseases is indexed in Scopus and DOAJ.
Is Genes and Diseases open access, and what is the APC?
Genes and Diseases is a fully open-access journal. APC about USD 2,500.
Sources and updates
The facts on this page come from LetPub, OpenAlex, DOAJ, Publisher website; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-26). Last updated: .