Journal profile · Medicine, General & Internal
European Journal of Clinical Investigation
ISSN 0014-2972 · eISSN 1365-2362 · Wiley-Blackwell Publishing Ltd · GERMANY · Monthly · Founded 1970
European Journal of Clinical Investigation: CAS Zone 3 · Medicine (2025 upgraded edition); impact factor 4.07; hybrid open access; APC about USD 4,100; median 75 days to acceptance (82 articles, last 24 months); community-reported acceptance: about 50%; 209 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
European Journal of Clinical Investigation is published by Wiley-Blackwell Publishing Ltd and is in Zone 3 of Medicine in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Diabetes, Cardiovascular Risks, and Lipoproteins, Lipoproteins and Cardiovascular Health and Adipokines, Inflammation, and Metabolic Diseases, together about 24.9% of its articles. Its main subfields are Physiology. (generated from OpenAlex topic counts and CAS ranking data)
EJCI considers any original contribution from the most sophisticated basic molecular sciences to applied clinical and translational research and evidence-based medicine across a broad range of subspecialties. The EJCI publishes reports of high-quality research that pertain to the genetic, molecular, cellular, or physiological basis of human biology and disease, as well as research that addresses prevalence, diagnosis, course, treatment, and prevention of disease. We are primarily interested in studies directly pertinent to humans, but submission of robust in vitro and animal work is also encouraged. Interdisciplinary work and research using innovative methods and combinations of laboratory, clinical, and epidemiological methodologies and techniques is of great interest to the journal. Several categories of manuscripts (for detailed description see below) are considered: editorials, original articles (also including randomized clinical trials, systematic reviews and meta-analyses), reviews (narrative reviews), opinion articles (including debates, perspectives and commentaries); and letters to the Editor.
From the journal's Aims & Scope
Research area (LetPub): Medicine, General & Internal
Editor-in-chief Fabrizio Montecucco GenoaPublisher website
Editorial board by country: none in mainland China; most named Italy 11, United States 5, Netherlands 3, Switzerland 3, Portugal 3 (36 members with a country) Editorial board ↗Publisher website ·
Main research topics OpenAlex counts of recent articles; shares are approximate
- Diabetes, Cardiovascular Risks, and LipoproteinsMedicine10.6%
- Lipoproteins and Cardiovascular HealthMedicine7.6%
- Adipokines, Inflammation, and Metabolic DiseasesMedicine6.7%
- Liver Disease Diagnosis and TreatmentMedicine6%
- Cardiovascular Function and Risk FactorsMedicine4.8%
- Nitric Oxide and Endothelin EffectsMedicine4.1%
- Drug Transport and Resistance MechanismsMedicine3.9%
- Diet and metabolism studiesMedicine3.9%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 3
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 3 |
| Minor | Medicine, General & Internal | Zone 2 |
| Minor | Medicine, Research & Experimental | Zone 3 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Medicine Zone 3
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 3 |
| Minor | Medicine, General & Internal | Zone 2 |
| Minor | Medicine, Research & Experimental | Zone 3 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 3
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 3 |
| Minor | Medicine, General & Internal | Zone 3 |
| Minor | Medicine, Research & Experimental | Zone 3 |
Top journal: noReview journal: no
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Indexing the journal's website claims
MEDLINEPubMedEmbaseCAB AbstractsCurrent ContentsPublisher website
Other: EBSCO
As the journal's website lists them, not checked against each database; for Web of Science editions the records above apply.
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 4.07LetPub ·
- Impact factor (publisher)
- 4.1Publisher website ·
- Impact factor (publisher) 2025
- 4.1Publisher website ·
- CiteScore 2026-06
- 7.9LetPub ·
- CiteScore (publisher)
- 7.9Publisher website ·
- CiteScore (publisher) 2025
- 7.9Publisher website ·
- SJR 2026-06
- 1.27LetPub ·
- SNIP 2026-06
- 1.04LetPub ·
- h-index
- 98LetPub ·
- h-index
- 167OpenAlex ·
- i10-index
- 5,176OpenAlex ·
- 2-year mean citedness
- 4.78OpenAlex ·
- Self-citation rate
- 4.9%LetPub ·
- Share of gold OA articles
- 49.9%LetPub ·
Volume
- Articles per year
- 162LetPub ·
- Articles per year (publisher)
- 2Publisher website ·
- Articles per year (publisher) 2025
- 176Publisher website ·
- Downloads per year (publisher) 2025
- 640,673Publisher website ·
Articles by year OpenAlex count · 8,627 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 104 | 59 | 61 |
| 2025 | 209 | 150 | 867 |
| 2024 | 238 | 170 | 1,704 |
| 2023 | 211 | 133 | 2,002 |
| 2022 | 224 | 119 | 3,078 |
| 2021 | 275 | 145 | 5,486 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with Crossref · to
75 daysMedian, submission to acceptance · P25–P75 55 days – 100 days
- Acceptance to online
- median 15 days (85 articles)
- Submission to online
- median 92 days
- Sample
- 82 articles with submission and acceptance dates (351 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Average review time (community reports)
- about 1 monthLetPub ·
- Average acceptance (community reports)
- 50%LetPub ·
- Acceptance rate (publisher)
- 6%Publisher website ·
- Acceptance rate (publisher) 2025
- 6%Publisher website ·
- Submission to first decision
- 2 daysPublisher website ·
- Submission to first decision 2025
- 2 daysPublisher website ·
- Submission to acceptance 2025
- 70 daysPublisher website ·
- Acceptance to publication 2025
- 17 daysPublisher website ·
- Peer review
- Single anonymous peer reviewPublisher website
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Hybrid open accessLetPub
A subscription journal in which authors can pay to publish their article open access.
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| OpenAlex | USD 4,100 / EUR 3,400 / GBP 2,720 | — | — | |
| Publisher website | Yes, amount not published | — | — |
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
What to prepare3 items from the author guidelines
- Manuscript length
- ≤ 3,500 words
- Suggested reviewers
- Required, 4
- Cover letter
- Required
Article types accepted6, with length limits
- clinical trialClinical TrialIn this particular type of original study, individuals are randomly allocated to receive or not receive a preventive, therapeutic, or diagnostic i…Length not stated
- hypothesisSection 4: Article TypesOriginal ArticleThese reports typically include basic research, clinical and translational studies which describe substantial new mechan…Length not stated
- letterpic of your research is clear. Research Letters are generally limited to 2000 words (not including tables, figures, and references), 15 referenmain text ≤ 2,000 words
- protocolSection 4: Article TypesOriginal ArticleThese reports typically include basic research, clinical and translational studies which describe substantial new mechan…Length not stated
- research articleSection 4: Article TypesOriginal ArticleThese reports typically include basic research, clinical and translational studies which describe substantial new mechan…main text ≤ 3,500 words
- research reportSection 4: Article TypesOriginal ArticleThese reports typically include basic research, clinical and translational studies which describe substantial new mechan…Length not stated
Policy excerpts from the journal's websiteAuthorship, Data availability, Publication ethics, Open access, Peer review, Preprints
- Authorship Authorship
All listed authors should have contributed to the manuscript substantially and have agreed to the final submitted version. Review editorial standards and scroll down for a description of authorship criteria.
Source ↗Publisher website ·- Data availability Data Sharing and Data Availability
This journal encourages data sharing. Review Wiley’s Data Sharing policy where you will be able to see and select the data availability statement that is right for your submission.
Source ↗Publisher website ·- Publication ethics Ethical Considerations on Artificial Intelligence, Health and Health Care. All That Glisters Is Not Gold
Piero Portincasa, Mohamad Khalil, Pierfrancesco Novielli, Sabina Tangaro,
Source ↗Publisher website ·- Open access Section 2: Open Access
This journal is a subscription journal that offers an open access option. You’ll have the option to choose to make your article open access after acceptance, which will be subject to an article processing charge (APC), unless a waiver applies. Check with your institution whether an agreement exist with Wiley regarding payment of the APC. Read more about APCs here.
Source ↗Publisher website ·- Peer review 1. Submission and Peer Review Process
Single-blind peer review model Model summary
Section 1: Submissions Once the submission materials have been prepared in accordance with the Author Guidelines, manuscripts should be submitted online at https://authors.wiley.com/journal/ECI At first submissions EJCI requires a pdf including all mandatory material referenced in Section 3. After acceptance, we will request that you provide the separate, high-quality editable tables and high-qual…
Source ↗Publisher website ·- Preprints
Preprint policy Model summary
This journal accepts articles previously published on preprint servers.
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- Wiley-Blackwell Publishing Ltd
- Country or region
- GERMANY
- Language
- English
- Frequency
- Monthly
- Founded
- 1970
- ISSN
- 0014-2972
- Electronic ISSN
- 1365-2362
- Society / sponsor
- European Society for Clinical Investigation
- Latest issue on the website
- Volume 56, Issue 9 (September 2026)
- Official links
- Journal homepage ↗OpenAlex
- Submission system ↗LetPub
- Special issues ↗Publisher website
FAQ
Frequently asked questions about European Journal of Clinical Investigation
What CAS zone is European Journal of Clinical Investigation in?
In the 2025 upgraded edition of the CAS Journal Ranking, European Journal of Clinical Investigation is in Zone 3 of Medicine, and in Zone 2 of the minor category Medicine, General & Internal / Medicine, Research & Experimental. In the 2026 Xinrui edition it is in Zone 3 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of European Journal of Clinical Investigation?
The latest impact factor listed by LetPub is 4.07; CiteScore 7.9, h-index 167.
How long does peer review take at European Journal of Clinical Investigation?
Based on the dates recorded on 82 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 75 days (interquartile range 55–100 days); authors report an average review time of about 1 month; the community-reported acceptance is “about 50%”; the journal's website gives an acceptance rate of 6% (2025). Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
What are the manuscript requirements of European Journal of Clinical Investigation?
According to the journal's author guidelines: Manuscript length: ≤ 3,500 words; Suggested reviewers: Required, 4; Cover letter: Required. A model extracted these from the author guidelines and each was checked against the text; check the latest version on the journal's website before submitting.
Where are the editorial board members of European Journal of Clinical Investigation based?
Of the 36 board members whose country the journal's board page names, none are in mainland China; the countries named most often are Italy (11), United States (5) and Netherlands (3). Counted from the institutions listed on the board page; for reference only.
Which databases index European Journal of Clinical Investigation?
According to LetPub and DOAJ records, European Journal of Clinical Investigation is indexed in SCIE and Scopus. The journal's website also lists MEDLINE, PubMed, Embase, CAB Abstracts and Current Contents; that list has not been checked against each database.
Is European Journal of Clinical Investigation open access, and what is the APC?
European Journal of Clinical Investigation is a hybrid journal. For open-access publication: APC about USD 4,100.
Sources and updates
The facts on this page come from LetPub, Publisher website, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-26). Last updated: .