Journal profile · Computer Science, Interdisciplinary Applications
Computational Biology and Chemistry
ISSN 1476-9271 · eISSN 1476-928X · Elsevier Ltd · ENGLAND · Bimonthly · Founded 2003
Computational Biology and Chemistry: CAS Zone 4 · Biology (2025 upgraded edition); impact factor 3.29; hybrid open access; APC about USD 3,320; median 95 days to acceptance (102 articles, last 24 months); community-reported acceptance: fairly easy; 483 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
Computational Biology and Chemistry is published by Elsevier Ltd and is in Zone 4 of Biology in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Computational Drug Discovery Methods, Machine Learning in Bioinformatics and Bioinformatics and Genomic Networks, together about 32.2% of its articles. Its main subfields are Molecular Biology. (generated from OpenAlex topic counts and CAS ranking data)
Computational Biology and Chemistry publishes high quality full-length articles and review articles in all areas of computational life sciences. It covers a very wide range of areas of research, including:Nucleic Acid and Protein Sequence ResearchMolecular EvolutionMolecular Genetics (Functional Genomics and Proteomics)Biology-Specific Modeling Theory and PracticeChemical-Biology-Specific Modeling Theory and PracticeStructural Biology of Nucleic Acids and ProteinsBioinformaticsSystems BiologyEcologyComputational PharmacologyComputational Molecular BiophysicsMetabolismBiomedical EngineeringEpidemiologyStatistical GeneticsInnovative AI methodologies for biological data, biomolecular modelling and machine learning modelsGiven their inherent uncertainty, protein modeling and molecular docking studies should be thoroughly validated. In the absence of experimental results for validation, the use of molecular dynamics simulations along with detailed free energy calculations, for example, should be used as complementary techniques to support the major conclusions. Submissions of premature modeling exercises without additional biological insights will not be considered.
From the journal's Aims & Scope
Research area (LetPub): Computer Science, Interdisciplinary Applications
Editor-in-chief Donald Hamelberg GeorgiaPublisher website
Editorial board by country: 6 in mainland China (about 12%); most named United States 19, Mainland China 6, India 6, United Kingdom 4, Germany 2 (50 members with a country) Editorial board ↗Publisher website ·
Main research topics OpenAlex counts of recent articles; shares are approximate
- Computational Drug Discovery MethodsComputer Science14.5%
- Machine Learning in BioinformaticsBiochemistry, Genetics and Molecular Biology9.7%
- Bioinformatics and Genomic NetworksBiochemistry, Genetics and Molecular Biology8%
- Protein Structure and DynamicsBiochemistry, Genetics and Molecular Biology7.6%
- RNA and protein synthesis mechanismsBiochemistry, Genetics and Molecular Biology7.4%
- Genomics and Phylogenetic StudiesBiochemistry, Genetics and Molecular Biology5.6%
- Gene expression and cancer classificationBiochemistry, Genetics and Molecular Biology4.8%
- Educational Robotics and EngineeringComputer Science3.9%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Biology Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 4 |
| Minor | Biology | Zone 4 |
| Minor | Computer Science, Interdisciplinary Applications | Zone 4 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Biology Zone 3
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 3 |
| Minor | Biology | Zone 3 |
| Minor | Computer Science, Interdisciplinary Applications | Zone 4 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Biology Zone 4
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 4 |
| Minor | Biology | Zone 4 |
| Minor | Computer Science, Interdisciplinary Applications | Zone 4 |
Top journal: noReview journal: no
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 3.29LetPub ·
- Impact factor (publisher)
- 3.4Publisher website ·
- CiteScore 2026-06
- 5.2LetPub ·
- CiteScore (publisher)
- 5.2Publisher website ·
- SJR 2026-06
- 0.56LetPub ·
- SNIP 2026-06
- 0.77LetPub ·
- h-index
- 55LetPub ·
- h-index
- 76OpenAlex ·
- i10-index
- 1,280OpenAlex ·
- 2-year mean citedness
- 2.91OpenAlex ·
- Self-citation rate
- 5.9%LetPub ·
- Share of gold OA articles
- 9.99%LetPub ·
Volume
- Articles per year
- 460LetPub ·
Articles by year OpenAlex count · 3,749 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 526 | 68 | 235 |
| 2025 | 483 | 62 | 1,725 |
| 2024 | 277 | 40 | 1,778 |
| 2023 | 160 | 36 | 1,761 |
| 2022 | 148 | 36 | 1,817 |
| 2021 | 142 | 31 | 1,766 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with PubMed · to
95 daysMedian, submission to acceptance · P25–P75 67 days – 127 days
- Acceptance to online
- median 3 days (102 articles)
- Submission to online
- median 100 days
- Sample
- 102 articles with submission and acceptance dates (1,118 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Average review time (community reports)
- about 15 monthsLetPub ·
- Average acceptance (community reports)
- Fairly easyLetPub ·
- Submission to first decision
- 6 daysPublisher website ·
- First decision after review
- 42 daysPublisher website ·
- Submission to acceptance
- 84 daysPublisher website ·
- Acceptance to publication
- 5 daysPublisher website ·
- Peer review
- Single anonymous peer reviewPublisher website
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Hybrid open accessLetPub
A subscription journal in which authors can pay to publish their article open access.
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| OpenAlex | USD 3,320 / EUR 3,110 / GBP 2,660 / JPY 411,780 | — | — | |
| Publisher website | USD 3,200 | — | — |
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
Open calls for papers1, by deadline
Publisher websiteArticle types accepted3
- full-length articlesFull-length articles are original scientific papers describing research in any of the above areas.Length not stated
- review articleFull-length articles are original scientific papers describing research in any of the above areas. Abstract should succinctly summarize the research, including …Length not stated
- review articlesReview articles will generally be commissioned by the editors and should not be submitted to the journal without explicit invitation.Length not stated
Policy excerpts from the journal's websiteAI use, Authorship, Conflicts of interest, License & copyright, Open access, Peer review, Preprints
- AI use Declaration of generative AI use
Authors must declare the use of generative AI tools in the manuscript preparation process upon submission of the paper.Generative AI and AI-assisted technologies (“AI tools”) have been rapidly adopted in research and scholarly publishing, offering significant benefits while requiring clear standards for responsible and transparent use.Authors preparing a manuscript for this journal may use AI tool…
Source ↗Publisher website ·- Authorship Group authorship
Group authorship refers to the attribution of an article to a defined and named group of authors whose members have contributed to the work. Examples include research consortia, clinical trial groups, collaborative networks, task forces or working groups, expert panels or consensus groups, and participatory research groups. Group authorship must be declared on the title page at submission. When av…
Source ↗Publisher website ·- Conflicts of interest Declaration of competing interests
All authors must disclose any financial and personal relationships with other people or organizations that could inappropriately influence or bias their work. Examples of potential competing interests include:EmploymentConsultanciesStock ownershipHonorariaPaid expert testimonyPatent applications or registrationsGrants or any other fundingAffiliation with the journal as an Editor or Advisory Board …
Source ↗Publisher website ·- License & copyright License options
Authors will be offered open access user license options which will determine how you, and third parties, can reuse your open access article. We advise that you review these options and any funding body license requirements before selecting a license option.
Source ↗Publisher website ·- Open access Open access
We refer you to our open access information page to learn about open access options for this journal.
Source ↗Publisher website ·- Peer review Peer review
Single anonymized review process Model summary
This journal follows a single anonymized review process. Your submission will initially be assessed by our editors. If your submission is deemed suitable, it will typically be sent to be reviewed by a minimum of two reviewers for an independent expert assessment of the scientific quality. The decision as to whether your article is accepted or rejected for publication will be made by our editors.Re…
Source ↗Publisher website ·- Preprints Preprints
Preprint sharing allowed Model summary
Preprint sharingAuthors may share preprints in line with Elsevier's article sharing policy. Sharing preprints, such as on a preprint server, will not count as prior publication.We advise you to read our policy on multiple, redundant or concurrent publication.
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- Elsevier Ltd
- Country or region
- ENGLAND
- Language
- English
- Frequency
- Bimonthly
- Founded
- 2003
- ISSN
- 1476-9271
- Electronic ISSN
- 1476-928X
- Official links
- Journal homepage ↗OpenAlex
- Submission system ↗Publisher website
- Special issues ↗Publisher website
FAQ
Frequently asked questions about Computational Biology and Chemistry
What CAS zone is Computational Biology and Chemistry in?
In the 2025 upgraded edition of the CAS Journal Ranking, Computational Biology and Chemistry is in Zone 4 of Biology, and in Zone 4 of the minor category Biology / Computer Science, Interdisciplinary Applications. In the 2026 Xinrui edition it is in Zone 3 of Biology. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Computational Biology and Chemistry?
The latest impact factor listed by LetPub is 3.29; CiteScore 5.2, h-index 76.
How long does peer review take at Computational Biology and Chemistry?
Based on the dates recorded on 102 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 95 days (interquartile range 67–127 days); authors report an average review time of about 15 months; the community-reported acceptance is “Fairly easy”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
Where are the editorial board members of Computational Biology and Chemistry based?
Of the 50 board members whose country the journal's board page names, 6 (about 12%) are in mainland China; the countries named most often are United States (19), Mainland China (6) and India (6). Counted from the institutions listed on the board page; for reference only.
Which databases index Computational Biology and Chemistry?
According to LetPub and DOAJ records, Computational Biology and Chemistry is indexed in SCIE and Scopus.
Is Computational Biology and Chemistry open access, and what is the APC?
Computational Biology and Chemistry is a hybrid journal. For open-access publication: APC about USD 3,320.
Sources and updates
The facts on this page come from LetPub, Publisher website, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-26). Last updated: .