Journal profile · Zoology
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
ISSN 1532-0456 · eISSN 1878-1659 · Elsevier Inc. · UNITED STATES · Monthly · Founded 2000
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY: CAS Zone 3 · Environmental Science & Ecology (2025 upgraded edition); impact factor 4.38; hybrid open access; APC about USD 3,220; median 113 days to acceptance (112 articles, last 24 months); community-reported acceptance: fairly easy; 240 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY is published by Elsevier Inc. and is in Zone 3 of Environmental Science & Ecology in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Environmental Toxicology and Ecotoxicology, Aquaculture Nutrition and Growth and Physiological and biochemical adaptations, together about 33.1% of its articles. (generated from OpenAlex topic counts and CAS ranking data)
Comparative Biochemistry & Physiology (CBP) publishes papers in comparative, environmental and evolutionary physiology.Part C: Toxicology and Pharmacology (CBPC), focuses on toxicological mechanisms at different levels of organization, primarily chemical and drug action, biotransformation of xenobiotics, endocrine disruptors, nanoparticles, pharmaceuticals, and natural products chemistry. Most studies employ a molecular approach in combination with observations of higher levels of organization to assess the mechanism by which xenobiotics affect physiology. Analytical verification of exposure concentrations is strongly recommended for manuscripts reporting toxicological studies.All four CBP journals support and follow the editorial direction from all the major societies in the field:Australia & New Zealand Society of Comparative Physiology and Biochemistry (ANZSCPB)American Physiological Society (APS)Canadian Society of Zoologists (CSZ)Deutsche Zoologische Gesellschaft (DZG)European Society of Comparative Physiology and Biochemistry (ESCPB)Japanese Society for Comparative Physiology and Biochemistry (JSCPB)South American Society for Comparative Physiology and Biochemistry (SASCPB)Societe de Physiologie (SDP)Society for Experimental Biology (SEB)Society for Integrative & Comparative Biology (SICB)CBP journals are focused on promoting the authors and the work published in the journal:All articles are carefully evaluated directly by the Editors-in-Chief who are leading experts in their field.Availability: contact the Editor-in-Chief for any questions you may have.The Journal will provide upon request free PDFs to all authors who may not have access to their articles via their institution or library.Publication is free to authors (no color or page charges).Supporting open access: if your funding body or institution requires your article to be open access, CBP offers that option. Please see details here.Reuse figures from any CBP article via "get rights and content" hyperlink available within each article (below author names and affiliations) on ScienceDirect.Please click here for more information on more general author services.Other CBP journals Part A (CBPA): Molecular & Integrative Physiology Part B (CBPB): Biochemistry & Molecular Biology Part D (CBPD): Genomics & Proteomics
From the journal's Aims & Scope
Research area (LetPub): Zoology
Editor-in-chief Martin GrosellPublisher website
Editorial board by country: 13 in mainland China (about 15%); most named Canada 23, United States 22, Mainland China 13, Japan 6, United Kingdom 3 (86 members with a country) Editorial board ↗Publisher website ·
Main research topics OpenAlex counts of recent articles; shares are approximate
- Environmental Toxicology and EcotoxicologyEnvironmental Science20.5%
- Aquaculture Nutrition and GrowthAgricultural and Biological Sciences7.2%
- Physiological and biochemical adaptationsEnvironmental Science5.4%
- Reproductive biology and impacts on aquatic speciesBiochemistry, Genetics and Molecular Biology5.4%
- Aquaculture disease management and microbiotaImmunology and Microbiology5.2%
- Pharmaceutical and Antibiotic Environmental ImpactsEnvironmental Science4.3%
- Human auditory perception and evaluationEngineering4.2%
- Diverse Scientific and Economic StudiesEconomics, Econometrics and Finance4.1%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Environmental Science & Ecology Zone 3
| Level | Category | Zone |
|---|---|---|
| Major | Environmental Science & Ecology | Zone 3 |
| Minor | Toxicology | Zone 2 |
| Minor | Zoology | Zone 2 |
| Minor | Biochemistry & Molecular Biology | Zone 3 |
| Minor | Endocrinology & Metabolism | Zone 3 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Environmental Science & Ecology Zone 3
| Level | Category | Zone |
|---|---|---|
| Major | Environmental Science & Ecology | Zone 3 |
| Minor | Biochemistry & Molecular Biology | Zone 3 |
| Minor | Endocrinology & Metabolism | Zone 3 |
| Minor | Toxicology | Zone 2 |
| Minor | Zoology | Zone 1 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Environmental Science & Ecology Zone 3
| Level | Category | Zone |
|---|---|---|
| Major | Environmental Science & Ecology | Zone 3 |
| Minor | Toxicology | Zone 2 |
| Minor | Zoology | Zone 2 |
| Minor | Biochemistry & Molecular Biology | Zone 3 |
| Minor | Endocrinology & Metabolism | Zone 3 |
Top journal: noReview journal: no
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 4.38LetPub ·
- Impact factor (publisher)
- 4.4Publisher website ·
- CiteScore 2026-06
- 9.2LetPub ·
- CiteScore (publisher)
- 9.2Publisher website ·
- SJR 2026-06
- 1.11LetPub ·
- SNIP 2026-06
- 1.03LetPub ·
- h-index
- 99LetPub ·
- h-index
- 132OpenAlex ·
- i10-index
- 2,525OpenAlex ·
- 2-year mean citedness
- 3.27OpenAlex ·
- Self-citation rate
- 4.5%LetPub ·
- Share of gold OA articles
- 12.88%LetPub ·
Volume
- Articles per year
- 223LetPub ·
Articles by year OpenAlex count · 4,234 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 197 | 36 | 61 |
| 2025 | 240 | 40 | 662 |
| 2024 | 211 | 53 | 1,394 |
| 2023 | 210 | 44 | 2,659 |
| 2022 | 212 | 42 | 3,794 |
| 2021 | 217 | 34 | 4,356 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with PubMed · to
113 daysMedian, submission to acceptance · P25–P75 76 days – 159 days
- Acceptance to online
- median 2 days (112 articles)
- Submission to online
- median 115 days
- Sample
- 112 articles with submission and acceptance dates (510 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Average review time (community reports)
- about 1 monthLetPub ·
- Average acceptance (community reports)
- Fairly easyLetPub ·
- Submission to first decision
- 3 daysPublisher website ·
- First decision after review
- 47 daysPublisher website ·
- Submission to acceptance
- 99 daysPublisher website ·
- Acceptance to publication
- 3 daysPublisher website ·
- Peer review
- Single anonymous peer reviewPublisher website
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Hybrid open accessLetPub
A subscription journal in which authors can pay to publish their article open access.
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| OpenAlex | USD 3,220 / EUR 3,010 / GBP 2,580 / JPY 399,380 | — | — | |
| Publisher website | USD 3,460 | — | — |
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
Other charges and waivers (author guidelines)
- Colour charges
- No colour charges
- Page charges
- No page charges
- Submission fee
- No submission fee
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
What to prepare6 items from the author guidelines
- Abstract
- ≤ 250 words
- Keywords
- 1–7
- Manuscript length
- ≤ 8,000 words
- Reference style
- Numbered, in order of citation
- Highlights
- Required
- Graphical abstract
- Required
Article types accepted8
- brief communicationA research paper is a paper that focuses on an experimental question of broad interest to the comparative physiology community.Word count (excluding references)…Length not stated
- editorialA research paper is a paper that focuses on an experimental question of broad interest to the comparative physiology community.Word count (excluding references)…Length not stated
- methods articleA research paper is a paper that focuses on an experimental question of broad interest to the comparative physiology community.Word count (excluding references)…Length not stated
- regular articleA research paper is a paper that focuses on an experimental question of broad interest to the comparative physiology community.Word count (excluding references)…Length not stated
- research paperA research paper is a paper that focuses on an experimental question of broad interest to the comparative physiology community.Word count (excluding references)…Length not stated
- reviewA research paper is a paper that focuses on an experimental question of broad interest to the comparative physiology community.Word count (excluding references)…Length not stated
- review articleA research paper is a paper that focuses on an experimental question of broad interest to the comparative physiology community.Word count (excluding references)…Length not stated
- short communicationA research paper is a paper that focuses on an experimental question of broad interest to the comparative physiology community.Word count (excluding references)…Length not stated
Policy excerpts from the journal's websiteAI use, Authorship, Conflicts of interest, License & copyright, Open access, Peer review, Preprints
- AI use Declaration of generative AI use
Authors must declare the use of generative AI tools in the manuscript preparation process upon submission of the paper.Generative AI and AI-assisted technologies (“AI tools”) have been rapidly adopted in research and scholarly publishing, offering significant benefits while requiring clear standards for responsible and transparent use.Authors preparing a manuscript for this journal may use AI tool…
Source ↗Publisher website ·- Authorship Group authorship
Group authorship refers to the attribution of an article to a defined and named group of authors whose members have contributed to the work. Examples include research consortia, clinical trial groups, collaborative networks, task forces or working groups, expert panels or consensus groups, and participatory research groups. Group authorship must be declared on the title page at submission. When av…
Source ↗Publisher website ·- Conflicts of interest Declaration of competing interests
All authors must disclose any financial and personal relationships with other people or organizations that could inappropriately influence or bias their work. Examples of potential competing interests include:EmploymentConsultanciesStock ownershipHonorariaPaid expert testimonyPatent applications or registrationsGrants or any other fundingAffiliation with the journal as an Editor or Advisory Board …
Source ↗Publisher website ·- License & copyright License options
Authors will be offered open access user license options which will determine how you, and third parties, can reuse your open access article. We advise that you review these options and any funding body license requirements before selecting a license option.
Source ↗Publisher website ·- Open access Open access
We refer you to our open access information page to learn about open access options for this journal.
Source ↗Publisher website ·- Peer review Peer review
Peer review type: single anonymized review process. Model summary
This journal follows a single anonymized review process. Your submission will initially be assessed by our editors. If your submission is deemed suitable, it will typically be sent to be reviewed by a minimum of one reviewer for an independent expert assessment of the scientific quality. The decision as to whether your article is accepted or rejected for publication will be made by our editors.Rea…
Source ↗Publisher website ·- Preprints Preprints
Preprint sharingAuthors may share preprints in line with Elsevier's article sharing policy. Sharing preprints, such as on a preprint server, will not count as prior publication.We advise you to read our policy on multiple, redundant or concurrent publication. In support of Open Science, this journal offers its authors a free preprint posting service on SSRN, Elsevier’s preprint and early research …
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- Elsevier Inc.
- Country or region
- UNITED STATES
- Language
- English
- Frequency
- Monthly
- Founded
- 2000
- ISSN
- 1532-0456
- Electronic ISSN
- 1878-1659
- Official links
- Journal homepage ↗LetPub
- Submission system ↗Publisher website
- Special issues ↗Publisher website
FAQ
Frequently asked questions about COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
What CAS zone is COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY in?
In the 2025 upgraded edition of the CAS Journal Ranking, COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY is in Zone 3 of Environmental Science & Ecology, and in Zone 2 of the minor category Toxicology / Zoology / Biochemistry & Molecular Biology / Endocrinology & Metabolism. In the 2026 Xinrui edition it is in Zone 3 of Environmental Science & Ecology. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY?
The latest impact factor listed by LetPub is 4.38; CiteScore 9.2, h-index 132.
How long does peer review take at COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY?
Based on the dates recorded on 112 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 113 days (interquartile range 76–159 days); authors report an average review time of about 1 month; the community-reported acceptance is “Fairly easy”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
What are the manuscript requirements of COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY?
According to the journal's author guidelines: Abstract: ≤ 250 words; Keywords: 1–7; Manuscript length: ≤ 8,000 words; Reference style: Numbered, in order of citation; Highlights: Required; Graphical abstract: Required. A model extracted these from the author guidelines and each was checked against the text; check the latest version on the journal's website before submitting.
Where are the editorial board members of COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY based?
Of the 86 board members whose country the journal's board page names, 13 (about 15%) are in mainland China; the countries named most often are Canada (23), United States (22) and Mainland China (13). Counted from the institutions listed on the board page; for reference only.
Which databases index COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY?
According to LetPub and DOAJ records, COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY is indexed in SCIE and Scopus.
Is COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY open access, and what is the APC?
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY is a hybrid journal. For open-access publication: APC about USD 3,220.
Sources and updates
The facts on this page come from LetPub, Publisher website, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-26). Last updated: .