Journal profile · Toxicology
Cell Biology and Toxicology
ISSN 0742-2091 · eISSN 1573-6822 · Springer Netherlands · UNITED STATES · Bimonthly · Founded 1984
Cell Biology and Toxicology: CAS Zone 3 · Medicine (2025 upgraded edition); impact factor 5.76; hybrid open access; APC about USD 4,190; median 130 days to acceptance (96 articles, last 24 months); community-reported acceptance: fairly easy; 160 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
Cell Biology and Toxicology is published by Springer Netherlands and is in Zone 3 of Medicine in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Carcinogens and Genotoxicity Assessment, RNA modifications and cancer and Cancer-related molecular mechanisms research, together about 20.7% of its articles. Its main subfields are Cancer Research. (generated from OpenAlex topic counts and CAS ranking data)
Cell Biology and Toxicology (CBT) is an international journal focused on clinical and translational research with an emphasis on molecular and cell biology, genetic and epigenetic heterogeneity, drug discovery and development, and molecular pharmacology and toxicology. CBT has a disease-specific scope prioritizing publications on gene and protein-based regulation, intracellular signaling pathway dysfunction, cell type-specific function, and systems in biomedicine in drug discovery and development. CBT publishes original articles with outstanding, innovative and significant findings, important reviews on recent research advances and issues of high current interest, opinion articles of leading edge science, and rapid communication or reports, on molecular mechanisms and therapies in diseases. SUBJECTS COVERED: 1. Gene and protein-based regulations in diseases CBT welcomes submissions in the fields of genomics and proteomic, functional genomics and proteomics, computational biology, and gene expression and function. CBT particularly includes aspects of the multifactorial genetics and epigenetics of diseases, disease-specific biomarkers, developmental biology, systems biology and bioinformatics-based data mining approaches with translational potentials. 2. Molecular pharmacology and toxicology CBT specially focuses on drug target identification and validation, rational drug design, genetic/small molecule (high-throughput) screening, novel therapeutic approaches, combinatorial and parallel synthesis of drugs, pharmacokinetics and pharmacodynamics, pharmacogenomics and toxicogenomics. 3. Pathological mechanisms related with intracellular organelles and cells CBT publishes novel findings on membrane biology and domains, and the associated receptor and non-receptor mediated signaling and transport proteins of the cell membrane, mitochondria, the endoplasmic reticulum, Golgi apparatus, and other organelles in health and disease. On the cellular and organism level, CBT aims to understanding cancer development, maintenance and treatment resistance, immune and inflammatory cell function, neuroscience, stem cell development and differentiation, epithelial biology and endothelial barrier function. 4. Biomedical aspects of organ systems in diseases CBT primarily publishes studies on the immune system, central and autonomic nervous systems, gastrointestinal system, cardiovascular and circulatory system, endocrine system, and pulmonary system, skeletal and muscular system,
From the journal's Aims & Scope
Research area (LetPub): Toxicology
Editor-in-chief Xiangdong WangPublisher website
Editorial board by country: 1 in mainland China (about 4%); most named United States 10, Germany 3, United Kingdom 2, Israel 2, Mainland China 1 (24 members with a country) Editorial board ↗Publisher website ·
Main research topics OpenAlex counts of recent articles; shares are approximate
- Carcinogens and Genotoxicity AssessmentBiochemistry, Genetics and Molecular Biology9.8%
- RNA modifications and cancerBiochemistry, Genetics and Molecular Biology5.9%
- Cancer-related molecular mechanisms researchBiochemistry, Genetics and Molecular Biology4.9%
- Human auditory perception and evaluationEngineering4.5%
- Heavy Metal Exposure and ToxicityEnvironmental Science4.4%
- Autophagy in Disease and TherapyMedicine4.3%
- Pharmacogenetics and Drug MetabolismPharmacology, Toxicology and Pharmaceutics4.3%
- MicroRNA in disease regulationBiochemistry, Genetics and Molecular Biology4.2%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 3
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 3 |
| Minor | Toxicology | Zone 1 |
| Minor | Cell Biology | Zone 3 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Medicine Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 2 |
| Minor | Cell Biology | Zone 3 |
| Minor | Toxicology | Zone 1 |
Top journal: noReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 2 |
| Minor | Toxicology | Zone 1 |
| Minor | Cell Biology | Zone 3 |
Top journal: noReview journal: no
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Indexing the journal's website claims
MEDLINEEmbaseCASCurrent ContentsPublisher website
Other: Google Scholar, EBSCO, ProQuest, Dimensions, CNKI, Baidu, AGRICOLA, Naver, OCLC, Portico, CLOCKSS
As the journal's website lists them, not checked against each database; for Web of Science editions the records above apply.
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 5.76LetPub ·
- Impact factor (publisher) 2025
- 5.7Publisher website ·
- 5-year impact factor (publisher) 2025
- 6.6Publisher website ·
- CiteScore 2026-06
- 10.6LetPub ·
- SJR 2026-06
- 1.66LetPub ·
- SNIP 2026-06
- 1.1LetPub ·
- h-index
- 56LetPub ·
- h-index
- 95OpenAlex ·
- i10-index
- 1,299OpenAlex ·
- 2-year mean citedness
- 5.83OpenAlex ·
- Self-citation rate
- 0%LetPub ·
- Share of gold OA articles
- 87.46%LetPub ·
Volume
- Articles per year
- 156LetPub ·
- Downloads per year (publisher) 2025
- 820,800Publisher website ·
Articles by year OpenAlex count · 2,282 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 151 | 151 | 87 |
| 2025 | 160 | 160 | 967 |
| 2024 | 128 | 128 | 1,506 |
| 2023 | 50 | 12 | 701 |
| 2022 | 109 | 45 | 2,892 |
| 2021 | 106 | 32 | 3,487 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with Crossref · to
130 daysMedian, submission to acceptance · P25–P75 96 days – 160 days
- Acceptance to online
- median 20 days (96 articles)
- Submission to online
- median 152 days
- Sample
- 96 articles with submission and acceptance dates (354 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Average review time (community reports)
- over 12 weeksLetPub ·
- Average acceptance (community reports)
- Fairly easyLetPub ·
- Submission to first decision
- 36 daysPublisher website ·
- Peer review
- Single anonymous peer review, Double anonymous peer reviewPublisher website
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Hybrid open accessLetPub
A subscription journal in which authors can pay to publish their article open access.
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| OpenAlex | USD 4,190 / EUR 3,390 / GBP 2,790 | — | — |
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
What to prepare4 items from the author guidelines
- Abstract
- 150–250 words
- Keywords
- ≥ 4
- Reference style
- Author–date
- Suggested reviewers
- Optional
Article types accepted8, with length limits
- editorialSingle-blind peer review This journal follows a single-blind reviewing procedure. Peer-review policy Peer-review is the system used to assess the quality of a m…Length not stated
- original article• Original Articles describe original research, and should be 3000-6000 words (excluding the abstract, tables, figure legends and references) and contain no mor…main text ≤ 6,000 words
- original articlesOriginal Articles describe original research, and should be 3000-6000 words (excluding the abstract, tables, figure legends and references) and contain no more …Length not stated
- original research• Original Articles describe original research, and should be 3000-6000 words (excluding the abstract, tables, figure legends and references) and contain no mor…Length not stated
- research paper• Original Articles describe original research, and should be 3000-6000 words (excluding the abstract, tables, figure legends and references) and contain no mor…Length not stated
- review• Original Articles describe original research, and should be 3000-6000 words (excluding the abstract, tables, figure legends and references) and contain no mor…Length not stated
- reviewsReviews should be a comprehensive synthesis and/or analysis of specific topics.Length not stated
- short communication• Original Articles describe original research, and should be 3000-6000 words (excluding the abstract, tables, figure legends and references) and contain no mor…Length not stated
Policy excerpts from the journal's websiteAI use, Authorship, Conflicts of interest, Data availability, Publication ethics, License & copyright, Open access, Peer review
- AI use Generative AI Images
Please check Springer’s policy on generative AI images and make sure your work adheres to the principles described therein. Back to top
Source ↗Publisher website ·- Authorship Authorship principles
These guidelines describe authorship principles and good authorship practices to which prospective authors should adhere to. Authorship clarified The Journal and Publisher assume all authors agreed with the content and that all gave explicit consent to submit and that they obtained consent from the responsible authorities at the institute/organization where the work has been carried out, before th…
Source ↗Publisher website ·- Conflicts of interest Disclosures and declarations
All authors are requested to include information regarding sources of funding, financial or non-financial interests, study-specific approval by the appropriate ethics committee for research involving humans and/or animals, informed consent if the research involved human participants, and a statement on welfare of animals if the research involved animals (as appropriate). The decision whether such …
Source ↗Publisher website ·- Data availability Data availability statements
ORCID required for corresponding author at submission. Model summary
All original research must include a data availability statement. This statement should explain how to access data supporting the results and analysis in the article, including links/citations to publicly archived datasets analysed or generated during the study. Please see our full policy here. If it is not possible to share research data publicly, for instance when individual privacy could be com…
Source ↗Publisher website ·- Publication ethics Compliance with Ethical Standards
LLMs cannot be authors; AI use must be documented. Model summary
To ensure objectivity and transparency in research and to ensure that accepted principles of ethical and professional conduct have been followed, authors should include information regarding sources of funding, potential conflicts of interest (financial or non-financial), informed consent if the research involved human participants, and a statement on welfare of animals if the research involved an…
Source ↗Publisher website ·- License & copyright Copyright
Copyright remains with authors (open access). Model summary
Articles in Springer Nature open access journals do not require transfer of copyright as the copyright remains with the author. Details of the OA licences offered to authors can be found on the individual journal website, in the journal's How to publish with us guide. Back to top
Source ↗Publisher website ·- Open access Open access publishing
To find out more about publishing your work Open Access in Cell Biology and Toxicology, including information on fees, funding and licences, visit our Open access publishing page. Back to top
Source ↗Publisher website ·- Peer review Peer-review policy
Single-blind peer review. Model summary
Peer-review is the system used to assess the quality of a manuscript before it is published. Independent researchers in the relevant research area assess submitted manuscripts for originality, validity and significance to help editors determine whether the manuscript should be published in their journal. Cell Biology and Toxicology operates a single-blind peer-review system, where the reviewers ar…
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- Springer Netherlands
- Country or region
- UNITED STATES
- Language
- English
- Frequency
- Bimonthly
- Founded
- 1984
- ISSN
- 0742-2091
- Electronic ISSN
- 1573-6822
- Official links
- Journal homepage ↗OpenAlex
- Submission system ↗LetPub
- Author guidelines ↗LetPub
- Special issues ↗Publisher website
FAQ
Frequently asked questions about Cell Biology and Toxicology
What CAS zone is Cell Biology and Toxicology in?
In the 2025 upgraded edition of the CAS Journal Ranking, Cell Biology and Toxicology is in Zone 3 of Medicine, and in Zone 1 of the minor category Toxicology / Cell Biology. In the 2026 Xinrui edition it is in Zone 2 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Cell Biology and Toxicology?
The latest impact factor listed by LetPub is 5.76; CiteScore 10.6, h-index 95.
How long does peer review take at Cell Biology and Toxicology?
Based on the dates recorded on 96 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 130 days (interquartile range 96–160 days); authors report an average review time of over 12 weeks; the community-reported acceptance is “Fairly easy”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
What are the manuscript requirements of Cell Biology and Toxicology?
According to the journal's author guidelines: Abstract: 150–250 words; Keywords: ≥ 4; Reference style: Author–date; Suggested reviewers: Optional. A model extracted these from the author guidelines and each was checked against the text; check the latest version on the journal's website before submitting.
Where are the editorial board members of Cell Biology and Toxicology based?
Of the 24 board members whose country the journal's board page names, 1 (about 4%) are in mainland China; the countries named most often are United States (10), Germany (3) and United Kingdom (2). Counted from the institutions listed on the board page; for reference only.
Which databases index Cell Biology and Toxicology?
According to LetPub and DOAJ records, Cell Biology and Toxicology is indexed in SCIE and Scopus. The journal's website also lists MEDLINE, Embase, CAS and Current Contents; that list has not been checked against each database.
Is Cell Biology and Toxicology open access, and what is the APC?
Cell Biology and Toxicology is a hybrid journal. For open-access publication: APC about USD 4,190.
Sources and updates
The facts on this page come from LetPub, OpenAlex, Publisher website; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .