Journal profile · Biochemistry & Molecular Biology

Cell Biochemistry and Biophysics

ISSN 1085-9195 · eISSN 1559-0283 · Springer US · UNITED STATES · Bimonthly · Founded 1979

Cell Biochemistry and Biophysics: CAS Zone 4 · Biology (2025 upgraded edition); impact factor 2.92; hybrid open access; APC about USD 3,990; median 82 days to acceptance (10 articles, last 24 months); community-reported acceptance: about 37.5%; 331 articles in 2025; indexed in SCIE and Scopus.

Impact factor2.92Latest value listed by LetPub
CAS zoneZone 4 · Biology2025 upgraded edition, major category · 2026 Xinrui edition Zone 3 · Biology
Review time82 daysMedian, submission to acceptance · 10 articles, last 24 months · PubMed
APCUSD 3,990Hybrid journal: charged only for open-access articles
Acceptanceabout 37.5%Community average
Articles per year3312025 · OpenAlex count

Scope

Aims, scope and focus

Cell Biochemistry and Biophysics is published by Springer US and is in Zone 4 of Biology in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are MicroRNA in disease regulation, Cancer-related molecular mechanisms research and RNA modifications and cancer, together about 20.9% of its articles. Its main subfields are Molecular Biology and Cancer Research. (generated from OpenAlex topic counts and CAS ranking data)

Cell Biochemistry and Biophysics (CBB) aims to publish papers on the nature of the biochemical and biophysical mechanisms underlying the structure, control and function of cellular systems The reports should be within the framework of modern biochemistry and chemistry, biophysics and cell physiology, physics and engineering, molecular and structural biology. The relationship between molecular structure and function under investigation is emphasized. Examples of subject areas that CBB publishes are:
· biochemical and biophysical aspects of cell structure and function;
· interactions of cells and their molecular/macromolecular constituents;
· innovative developments in genetic and biomolecular engineering;
· computer-based analysis of tissues, cells, cell networks, organelles, and molecular/macromolecular assemblies;
· photometric, spectroscopic, microscopic, mechanical, and electrical methodologies/techniques in analytical cytology, cytometry and innovative instrument design For articles that focus on computational aspects, authors should be clear about which docking and molecular dynamics algorithms or software packages are being used as well as details on the system parameterization, simulations conditions etc. In addition, docking calculations (virtual screening, QSAR, etc.) should be validated either by experimental studies or one or more reliable theoretical cross-validation methods. As to areas that we do not cover, we discourage clinical and epidemiological studies related to human health. We will consider papers on animal cell biology, but not plant species CBB also publishes reviews and minireviews, opinion papers, letters to the editor and proceedings of symposia. Former Editor-in-Chief: Lawrence Berliner, PhD, Department of Chemistry and Biochemistry, University of Denver, Denver, CO, United States of America

From the journal's Aims & Scope

Research area (LetPub): Biochemistry & Molecular Biology

Editor-in-chief Narasimham L. ParinandiPublisher website

Editorial board by country: 1 in mainland China (about 4%); most named United States 15, Japan 3, Mainland China 1, United Kingdom 1, India 1 (27 members with a country) Editorial board ↗Publisher website ·

Main research topics OpenAlex counts of recent articles; shares are approximate

  1. MicroRNA in disease regulationBiochemistry, Genetics and Molecular Biology7.9%
  2. Cancer-related molecular mechanisms researchBiochemistry, Genetics and Molecular Biology6.5%
  3. RNA modifications and cancerBiochemistry, Genetics and Molecular Biology6.5%
  4. Ion channel regulation and functionBiochemistry, Genetics and Molecular Biology5.4%
  5. Pancreatic function and diabetesMedicine5.2%
  6. Lipid Membrane Structure and BehaviorBiochemistry, Genetics and Molecular Biology4.4%
  7. Cancer, Hypoxia, and MetabolismBiochemistry, Genetics and Molecular Biology4.3%
  8. Ubiquitin and proteasome pathwaysBiochemistry, Genetics and Molecular Biology4.1%

Rankings & indexing

CAS ranking and database indexing

CAS Journal Ranking

CAS Journal Ranking, upgraded edition (March 2025)Biology Zone 4
LevelCategoryZone
MajorBiologyZone 4
MinorBiochemistry & Molecular BiologyZone 4
MinorBiophysicsZone 4
MinorCell BiologyZone 4

Top journal: noReview journal: no

CAS Xinrui Journal Ranking (March 2026)Biology Zone 3
LevelCategoryZone
MajorBiologyZone 3
MinorBiochemistry & Molecular BiologyZone 4
MinorBiophysicsZone 4
MinorCell BiologyZone 4

Top journal: noReview journal: not marked

CAS Journal Ranking, previous upgraded edition (December 2023)Biology Zone 4
LevelCategoryZone
MajorBiologyZone 4
MinorBiochemistry & Molecular BiologyZone 4
MinorBiophysicsZone 4
MinorCell BiologyZone 4

Top journal: noReview journal: no

Database indexing

SCIEScopusLetPub

International journal early-warning lists: not listed in any editionLetPub

Indexing the journal's website claims

MEDLINECASPublisher website

Other: Google Scholar, EBSCO, ProQuest, Dimensions, CNKI, Baidu, AGRICOLA, Naver, OCLC, Portico, CLOCKSS

As the journal's website lists them, not checked against each database; for Web of Science editions the records above apply.

Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.

Metrics

Impact metrics and publication volume

Impact

Impact factor
2.92LetPub ·
Impact factor (publisher) 2025
3Publisher website ·
5-year impact factor (publisher) 2025
2.8Publisher website ·
CiteScore 2026-06
3.3LetPub ·
SJR 2026-06
0.71LetPub ·
SNIP 2026-06
0.6LetPub ·
h-index
70LetPub ·
h-index
106OpenAlex ·
i10-index
1,761OpenAlex ·
2-year mean citedness
3.82OpenAlex ·
Self-citation rate
3.3%LetPub ·
Share of gold OA articles
8.94%LetPub ·

Volume

Articles per year
312LetPub ·
Downloads per year (publisher) 2025
662,100Publisher website ·

Articles by year OpenAlex count · 3,699 in total · the current year is incomplete

YearArticlesOpen accessCitations
20262044543
202533141889
2024433532,761
20238221710
20227513613
202189311,100

Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.

Review & acceptance

Review time and acceptance

Review time from article dates manuscript dates registered with PubMed · to

82 daysMedian, submission to acceptance · P25–P75 67 days – 127 days

Acceptance to online
median 23 days (121 articles)
Submission to online
median 113 days
Sample
10 articles with submission and acceptance dates (767 in the window); the latest was accepted on

Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".

Other sources

Average review time (community reports)
about 7.5 monthsLetPub ·
Average acceptance (community reports)
37.5%LetPub ·
Submission to first decision
1 daysPublisher website ·
Peer review
Double anonymous peer reviewPublisher website

Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.

Fees & open access

APC and open-access policy

Hybrid open accessLetPub

A subscription journal in which authors can pay to publish their article open access.

SourceAPCFee waiverLicenseObserved
OpenAlexUSD 3,990 / EUR 2,990 / GBP 2,590——
Publisher websiteNo APC——

A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.

Other charges and waivers (author guidelines)

Page charges
No page charges

The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.

Submission

Article types and submission policies (journal website)

What to prepare5 items from the author guidelines
Keywords
5–10
Reference style
Numbered, in order of citation
First submission
Free format: the journal's layout is not required
Suggested reviewers
Optional, 6
Not considered
alternative or traditional medicine
Publisher website · model-extracted, each line checked against the text
Article types accepted7, with length limits
  1. hypothesesHYPOTHESESLength not stated
  2. hypothesisCONTENT: • Hypotheses must be: (i) logical in the light of current knowledge and (ii) present a unique interpretation of current data not previously considered …Length not stated
  3. position papersDivide technical notes/position papers into: Abstract, Introduction, Discussion and Bibliography followed by the Figures and Tables.Length not stated
  4. research manuscriptsDivide research papers into: Abstract, Introduction, Materials and Methods, Results, DiscussionLength not stated
  5. reviewCONTENT: • Reviews must critically and thoroughly review a particular field and are expected to be as current as possible. • Reviews may contain unpublished dat…main text ≤ 200 words · abstract ≤ 200 words
  6. review manuscriptsReviews must critically and thoroughly review a particular field and are expected to be as current as possible.Length not stated
  7. technical notesDivide technical notes/position papers into: Abstract, Introduction, Discussion and Bibliography followed by the Figures and Tables.Length not stated
Publisher website
Policy excerpts from the journal's websiteAuthorship, Conflicts of interest, Data availability, Publication ethics, Open access, Peer review, Trial registration / reporting guidelines
Authorship Authorship principles

These guidelines describe authorship principles and good authorship practices to which prospective authors should adhere to. Authorship clarified The Journal and Publisher assume all authors agreed with the content and that all gave explicit consent to submit and that they obtained consent from the responsible authorities at the institute/organization where the work has been carried out, before th…

Source ↗Publisher website ·
Conflicts of interest Disclosures and declarations

All authors are requested to include information regarding sources of funding, financial or non-financial interests, study-specific approval by the appropriate ethics committee for research involving humans and/or animals, informed consent if the research involved human participants, and a statement on welfare of animals if the research involved animals (as appropriate). The decision whether such …

Source ↗Publisher website ·
Data availability Data availability statements

Data transparency requested Model summary

All original research must include a data availability statement. This statement should explain how to access data supporting the results and analysis in the article, including links/citations to publicly archived datasets analysed or generated during the study. Please see our full policy here. If it is not possible to share research data publicly, for instance when individual privacy could be com…

Source ↗Publisher website ·
Publication ethics Compliance with Ethical Standards

Simultaneous submission prohibited Model summary

To ensure objectivity and transparency in research and to ensure that accepted principles of ethical and professional conduct have been followed, authors should include information regarding sources of funding, potential conflicts of interest (financial or non-financial), informed consent if the research involved human participants, and a statement on welfare of animals if the research involved an…

Source ↗Publisher website ·
Open access Open access publishing

To find out more about publishing your work Open Access in Cell Biochemistry and Biophysics, including information on fees, funding and licences, visit our Open access publishing page. Back to top

Source ↗Publisher website ·
Peer review

Reviewer suggestions allowed Model summary

Authors are welcome to suggest suitable reviewers and/or request the exclusion of certain individuals when they submit their manuscripts.

Source ↗Publisher website ·
Trial registration / reporting guidelines Clinical Trial Registration

The World Health Organization (WHO) definition of a clinical trial is "any research study that prospectively assigns human participants or groups of humans to one or more health-related interventions to evaluate the effects on health outcomes". The WHO defines health interventions as “A health intervention is an act performed for, with or on behalf of a person or population whose purpose is to ass…

Source ↗Publisher website ·

Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.

Profile

Publication details and official links

Publisher
Springer US
Country or region
UNITED STATES
Language
English
Frequency
Bimonthly
Founded
1979
ISSN
1085-9195
Electronic ISSN
1559-0283
Latest issue on the website
Volume 84, Issue 2 (June 2026)
Official links

FAQ

Frequently asked questions about Cell Biochemistry and Biophysics

What CAS zone is Cell Biochemistry and Biophysics in?

In the 2025 upgraded edition of the CAS Journal Ranking, Cell Biochemistry and Biophysics is in Zone 4 of Biology, and in Zone 4 of the minor category Biochemistry & Molecular Biology / Biophysics / Cell Biology. In the 2026 Xinrui edition it is in Zone 3 of Biology. Zones from different editions, and from major and minor categories, are not interchangeable.

What is the impact factor of Cell Biochemistry and Biophysics?

The latest impact factor listed by LetPub is 2.92; CiteScore 3.3, h-index 106.

How long does peer review take at Cell Biochemistry and Biophysics?

Based on the dates recorded on 10 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 82 days (interquartile range 67–127 days); authors report an average review time of about 7.5 months; the community-reported acceptance is “about 37.5%”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.

What are the manuscript requirements of Cell Biochemistry and Biophysics?

According to the journal's author guidelines: Keywords: 5–10; Reference style: Numbered, in order of citation; First submission: Free format: the journal's layout is not required; Suggested reviewers: Optional, 6. A model extracted these from the author guidelines and each was checked against the text; check the latest version on the journal's website before submitting.

Where are the editorial board members of Cell Biochemistry and Biophysics based?

Of the 27 board members whose country the journal's board page names, 1 (about 4%) are in mainland China; the countries named most often are United States (15), Japan (3) and Mainland China (1). Counted from the institutions listed on the board page; for reference only.

Which databases index Cell Biochemistry and Biophysics?

According to LetPub and DOAJ records, Cell Biochemistry and Biophysics is indexed in SCIE and Scopus. The journal's website also lists MEDLINE and CAS; that list has not been checked against each database.

Is Cell Biochemistry and Biophysics open access, and what is the APC?

Cell Biochemistry and Biophysics is a hybrid journal. For open-access publication: APC about USD 3,990.

Sources and updates

The facts on this page come from LetPub, OpenAlex, Publisher website; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .