Journal profile · Biotechnology & Applied Microbiology

Biotechnology and Bioengineering

ISSN 0006-3592 · eISSN 1097-0290 · Wiley-VCH Verlag · UNITED STATES · Semimonthly

Biotechnology and Bioengineering: CAS Zone 3 · Biology (2025 upgraded edition); impact factor 3.87; hybrid open access; APC about USD 5,060; median 104 days to acceptance (106 articles, last 24 months); community-reported acceptance: 50%; 293 articles in 2025; indexed in SCIE and Scopus.

Impact factor3.87Latest value listed by LetPub
CAS zoneZone 3 · Biology2025 upgraded edition, major category · 2026 Xinrui edition Zone 3 · Biology
Review time104 daysMedian, submission to acceptance · 106 articles, last 24 months · Crossref
APCUSD 5,060Hybrid journal: charged only for open-access articles
Acceptance50%Community average
Articles per year2932025 · OpenAlex count

Scope

Aims, scope and focus

Biotechnology and Bioengineering is published by Wiley-VCH Verlag and is in Zone 3 of Biology in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Microbial Metabolic Engineering and Bioproduction, Viral Infectious Diseases and Gene Expression in Insects and Biofuel production and bioconversion, together about 35.2% of its articles. Its main subfields are Molecular Biology. (generated from OpenAlex topic counts and CAS ranking data)

Biotechnology & Bioengineering publishes Perspectives, Articles, Reviews, Mini-Reviews, and Communications to the Editor that embrace all aspects of biotechnology. These include: -Enzyme systems and their applications, including enzyme reactors, purification, and applied aspects of protein engineering -Animal-cell biotechnology, including media development -Applied aspects of cellular physiology, metabolism, and energetics -Biocatalysis and applied enzymology, including enzyme reactors, protein engineering, and nanobiotechnology -Biothermodynamics -Biofuels, including biomass and renewable resource engineering -Biomaterials, including delivery systems and materials for tissue engineering -Bioprocess engineering, including kinetics and modeling of biological systems, transport phenomena in bioreactors, bioreactor design, monitoring, and control -Biosensors and instrumentation -Computational and systems biology, including bioinformatics and genomic/proteomic studies -Environmental biotechnology, including biofilms, algal systems, and bioremediation -Metabolic and cellular engineering -Plant-cell biotechnology -Spectroscopic and other analytical techniques for biotechnological applications -Synthetic biology -Tissue engineering, stem-cell bioengineering, regenerative medicine, gene therapy and delivery systems The editors will consider papers for publication based on novelty, their immediate or future impact on biotechnological processes, and their contribution to the advancement of biochemical engineering science. Submission of papers dealing with routine aspects of bioprocessing, description of established equipment, and routine applications of established methodologies (e.g., control strategies, modeling, experimental methods) is discouraged. Theoretical papers will be judged based on the novelty of the approach and their potential impact, or on their novel capability to predict and elucidate experimental observations.

Source: LetPub

Research area (LetPub): Biotechnology & Applied Microbiology

Main research topics OpenAlex counts of recent articles; shares are approximate

  1. Microbial Metabolic Engineering and BioproductionBiochemistry, Genetics and Molecular Biology13.6%
  2. Viral Infectious Diseases and Gene Expression in InsectsBiochemistry, Genetics and Molecular Biology11.6%
  3. Biofuel production and bioconversionEngineering10.1%
  4. Enzyme Catalysis and ImmobilizationBiochemistry, Genetics and Molecular Biology9.1%
  5. Protein purification and stabilityBiochemistry, Genetics and Molecular Biology7.6%
  6. 3D Printing in Biomedical ResearchEngineering4.5%
  7. Enzyme Production and CharacterizationBiochemistry, Genetics and Molecular Biology4%
  8. Monoclonal and Polyclonal Antibodies ResearchMedicine3.5%

Rankings & indexing

CAS ranking and database indexing

CAS Journal Ranking

CAS Journal Ranking, upgraded edition (March 2025)Biology Zone 3
LevelCategoryZone
MajorBiologyZone 3
MinorBiotechnology & Applied MicrobiologyZone 3

Top journal: noReview journal: no

CAS Xinrui Journal Ranking (March 2026)Biology Zone 3
LevelCategoryZone
MajorBiologyZone 3
MinorBiotechnology & Applied MicrobiologyZone 3

Top journal: noReview journal: not marked

CAS Journal Ranking, previous upgraded edition (December 2023)Biology Zone 2
LevelCategoryZone
MajorBiologyZone 2
MinorBiotechnology & Applied MicrobiologyZone 2

Top journal: noReview journal: no

Database indexing

SCIEScopusLetPub

International journal early-warning lists: not listed in any editionLetPub

Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.

Metrics

Impact metrics and publication volume

Impact

Impact factor
3.87LetPub ·
CiteScore 2026-06
7.8LetPub ·
SJR 2026-06
0.88LetPub ·
SNIP 2026-06
0.98LetPub ·
h-index
171LetPub ·
h-index
272OpenAlex ·
i10-index
13,413OpenAlex ·
2-year mean citedness
3.79OpenAlex ·
Self-citation rate
5.1%LetPub ·
Share of gold OA articles
45.41%LetPub ·

Volume

Articles per year
252LetPub ·

Articles by year OpenAlex count · 19,868 in total · the current year is incomplete

YearArticlesOpen accessCitations
2026249169127
2025293183962
20242771812,013
20233242303,840
20223091235,180
20213901577,894

Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.

Review & acceptance

Review time and acceptance

Review time from article dates manuscript dates registered with Crossref · to

104 daysMedian, submission to acceptance · P25–P75 75 days – 141 days

Acceptance to online
median 13 days (106 articles)
Submission to online
median 118 days
Sample
106 articles with submission and acceptance dates (582 in the window); the latest was accepted on

Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".

Other sources

Average review time (community reports)
about 2.3 monthsLetPub ·
Average acceptance (community reports)
50%LetPub ·

Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.

Fees & open access

APC and open-access policy

Hybrid open accessLetPub

A subscription journal in which authors can pay to publish their article open access.

SourceAPCFee waiverLicenseObserved
OpenAlexUSD 5,060 / EUR 4,250 / GBP 3,330——

A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.

The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.

Profile

Publication details and official links

Publisher
Wiley-VCH Verlag
Country or region
UNITED STATES
Language
English
Frequency
Semimonthly
ISSN
0006-3592
Electronic ISSN
1097-0290
Official links

FAQ

Frequently asked questions about Biotechnology and Bioengineering

What CAS zone is Biotechnology and Bioengineering in?

In the 2025 upgraded edition of the CAS Journal Ranking, Biotechnology and Bioengineering is in Zone 3 of Biology, and in Zone 3 of the minor category Biotechnology & Applied Microbiology. In the 2026 Xinrui edition it is in Zone 3 of Biology. Zones from different editions, and from major and minor categories, are not interchangeable.

What is the impact factor of Biotechnology and Bioengineering?

The latest impact factor listed by LetPub is 3.87; CiteScore 7.8, h-index 272.

How long does peer review take at Biotechnology and Bioengineering?

Based on the dates recorded on 106 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 104 days (interquartile range 75–141 days); authors report an average review time of about 2.3 months; the community-reported acceptance is “50%”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.

Which databases index Biotechnology and Bioengineering?

According to LetPub and DOAJ records, Biotechnology and Bioengineering is indexed in SCIE and Scopus.

Is Biotechnology and Bioengineering open access, and what is the APC?

Biotechnology and Bioengineering is a hybrid journal. For open-access publication: APC about USD 5,060.

Sources and updates

The facts on this page come from LetPub, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-25). Last updated: .