Journal profile · Biochemistry & Molecular Biology
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
ISSN 0925-4439 · eISSN 1879-260X · Elsevier · NETHERLANDS · Monthly · Founded 1947
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE: CAS Zone 2 · Biology (2025 upgraded edition); impact factor 5.04; hybrid open access; APC about USD 4,010; median 146 days to acceptance (143 articles, last 24 months); community-reported acceptance: fairly hard; 434 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE is published by Elsevier and is in Zone 2 of Biology in the CAS Journal Ranking (2025 upgraded edition). By OpenAlex counts of its recent articles, its largest topics are Mitochondrial Function and Pathology, Alzheimer's disease research and treatments and Diverse Scientific and Economic Studies, together about 23% of its articles. (generated from OpenAlex topic counts and CAS ranking data)
BBA Molecular Basis of Disease addresses the biochemistry and molecular genetics of disease processes and models of human disease. This journal covers aspects of aging, cancer, metabolic-, neurological-, and immunological-based disease. Manuscripts focused on using animal models to elucidate biochemical and mechanistic insight in each of these conditions, are particularly encouraged. Manuscripts should emphasize the underlying mechanisms of disease pathways and provide novel contributions to the understanding and/or treatment of these disorders. Highly descriptive and method development submissions may be declined without full review. The submission of uninvited reviews to BBA - Molecular Basis of Disease is strongly discouraged, and any such uninvited review should be accompanied by a coverletter outlining the compelling reasons why the review should be considered.
Source: LetPub
Research area (LetPub): Biochemistry & Molecular Biology
Main research topics OpenAlex counts of recent articles; shares are approximate
- Mitochondrial Function and PathologyBiochemistry, Genetics and Molecular Biology11%
- Alzheimer's disease research and treatmentsMedicine6.1%
- Diverse Scientific and Economic StudiesEconomics, Econometrics and Finance5.8%
- Human auditory perception and evaluationEngineering5.5%
- Metabolism and Genetic DisordersBiochemistry, Genetics and Molecular Biology5.5%
- Adipose Tissue and MetabolismMedicine5.4%
- Educational Robotics and EngineeringComputer Science5.1%
- Autophagy in Disease and TherapyMedicine5%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Biology Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 2 |
| Minor | Biophysics | Zone 2 |
| Minor | Biochemistry & Molecular Biology | Zone 3 |
Top journal: noReview journal: no
CAS Xinrui Journal Ranking (March 2026)Biology Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 2 |
| Minor | Biochemistry & Molecular Biology | Zone 2 |
| Minor | Biophysics | Zone 1 |
Top journal: yesReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Biology Zone 2
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 2 |
| Minor | Biochemistry & Molecular Biology | Zone 2 |
| Minor | Biophysics | Zone 2 |
Top journal: noReview journal: no
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 5.04LetPub ·
- CiteScore 2026-06
- 7.1LetPub ·
- SJR 2026-06
- 1.45LetPub ·
- SNIP 2026-06
- 0.97LetPub ·
- h-index
- 128LetPub ·
- h-index
- 229OpenAlex ·
- i10-index
- 5,154OpenAlex ·
- 2-year mean citedness
- 4.92OpenAlex ·
- Self-citation rate
- 0%LetPub ·
- Share of gold OA articles
- 26.81%LetPub ·
Volume
- Articles per year
- 418LetPub ·
Articles by year OpenAlex count · 7,322 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 273 | 64 | 77 |
| 2025 | 434 | 193 | 1,880 |
| 2024 | 574 | 573 | 4,342 |
| 2023 | 308 | 308 | 4,726 |
| 2022 | 213 | 213 | 4,035 |
| 2021 | 202 | 202 | 5,553 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with PubMed · to
146 daysMedian, submission to acceptance · P25–P75 111 days – 191 days
- Acceptance to online
- median 2 days (143 articles)
- Submission to online
- median 148 days
- Sample
- 143 articles with submission and acceptance dates (858 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Average review time (community reports)
- 3–6 weeksLetPub ·
- Average acceptance (community reports)
- Fairly hardLetPub ·
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Hybrid open accessLetPub
A subscription journal in which authors can pay to publish their article open access.
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| OpenAlex | USD 4,010 / EUR 3,750 / GBP 3,210 / JPY 497,360 | — | — |
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Profile
Publication details and official links
- Publisher
- Elsevier
- Country or region
- NETHERLANDS
- Language
- Dutch
- Frequency
- Monthly
- Founded
- 1947
- ISSN
- 0925-4439
- Electronic ISSN
- 1879-260X
- Official links
- Journal homepage ↗OpenAlex
- Submission system ↗LetPub
FAQ
Frequently asked questions about BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
What CAS zone is BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE in?
In the 2025 upgraded edition of the CAS Journal Ranking, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE is in Zone 2 of Biology, and in Zone 2 of the minor category Biophysics / Biochemistry & Molecular Biology. In the 2026 Xinrui edition it is in Zone 2 of Biology. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE?
The latest impact factor listed by LetPub is 5.04; CiteScore 7.1, h-index 229.
How long does peer review take at BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE?
Based on the dates recorded on 143 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 146 days (interquartile range 111–191 days); authors report an average review time of 3–6 weeks; the community-reported acceptance is “Fairly hard”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
Which databases index BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE?
According to LetPub and DOAJ records, BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE is indexed in SCIE and Scopus.
Is BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE open access, and what is the APC?
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE is a hybrid journal. For open-access publication: APC about USD 4,010.
Sources and updates
The facts on this page come from LetPub, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-30). Last updated: .