Journal profile · Pathology
Annual Review of Pathology-Mechanisms of Disease
ISSN 1553-4006 · eISSN 1553-4014 · Annual Reviews Inc. · UNITED STATES · Annual · Founded 2006
Annual Review of Pathology-Mechanisms of Disease: CAS Zone 1 · Medicine (2025 upgraded edition, Top journal); impact factor 34.36; subscription journal; community-reported acceptance: very hard; 26 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
Annual Review of Pathology-Mechanisms of Disease is published by Annual Reviews Inc. and is in Zone 1 of Medicine in the CAS Journal Ranking (2025 upgraded edition, Top journal). By OpenAlex counts of its recent articles, its largest topics are Epigenetics and DNA Methylation, Cancer Genomics and Diagnostics and Liver Disease Diagnosis and Treatment, together about 22.7% of its articles. (generated from OpenAlex topic counts and CAS ranking data)
AIMS AND SCOPE OF JOURNAL: The Annual Review of Pathology: Mechanisms of Disease covers significant advances in our understanding of the initiation and progression of important human diseases. Emphasis is placed on current and evolving concepts of disease pathogenesis, molecular genetic and morphologic alterations associated with diseases, and clinical significance.  
From the journal's Aims & Scope
Research area (LetPub): Pathology
Main research topics OpenAlex counts of recent articles; shares are approximate
- Epigenetics and DNA MethylationBiochemistry, Genetics and Molecular Biology8.4%
- Cancer Genomics and DiagnosticsBiochemistry, Genetics and Molecular Biology7.5%
- Liver Disease Diagnosis and TreatmentMedicine6.8%
- Cancer Cells and MetastasisMedicine6.5%
- Immune cells in cancerImmunology and Microbiology5%
- Immune Cell Function and InteractionImmunology and Microbiology4.7%
- Lymphoma Diagnosis and TreatmentMedicine4%
- Cancer, Hypoxia, and MetabolismBiochemistry, Genetics and Molecular Biology4%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Medicine Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 1 |
| Minor | Pathology | Zone 1 |
Top journal: yesReview journal: yes
CAS Xinrui Journal Ranking (March 2026)Medicine Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 1 |
| Minor | Pathology | Zone 1 |
Top journal: yesReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Medicine Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Medicine | Zone 1 |
| Minor | Pathology | Zone 1 |
Top journal: noReview journal: yes
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 34.36LetPub ·
- CiteScore 2026-06
- 45.5LetPub ·
- SJR 2026-06
- 12.06LetPub ·
- SNIP 2026-06
- 8.59LetPub ·
- h-index
- 105LetPub ·
- h-index
- 184OpenAlex ·
- i10-index
- 383OpenAlex ·
- 2-year mean citedness
- 22.7OpenAlex ·
- Self-citation rate
- 0.6%LetPub ·
- Share of gold OA articles
- 100%LetPub ·
Volume
- Articles per year
- 20LetPub ·
Articles by year OpenAlex count · 456 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 7 | 1 | 8 |
| 2025 | 26 | 25 | 422 |
| 2024 | 17 | 17 | 705 |
| 2023 | 22 | 21 | 1,313 |
| 2022 | 24 | 23 | 3,749 |
| 2021 | 28 | 19 | 3,726 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
- Average acceptance (community reports)
- Very hardLetPub ·
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Subscription journalLetPub
A subscription journal: articles are read by subscription or purchase, and authors usually pay no publication charge.
No source has fee information yet; check the journal's website.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Profile
Publication details and official links
- Publisher
- Annual Reviews Inc.
- Country or region
- UNITED STATES
- Language
- English
- Frequency
- Annual
- Founded
- 2006
- ISSN
- 1553-4006
- Electronic ISSN
- 1553-4014
- Official links
- Journal homepage ↗LetPub
- Special issues ↗Publisher website
FAQ
Frequently asked questions about Annual Review of Pathology-Mechanisms of Disease
What CAS zone is Annual Review of Pathology-Mechanisms of Disease in?
In the 2025 upgraded edition of the CAS Journal Ranking, Annual Review of Pathology-Mechanisms of Disease is in Zone 1 of Medicine, and in Zone 1 of the minor category Pathology; it is a Top journal. In the 2026 Xinrui edition it is in Zone 1 of Medicine. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of Annual Review of Pathology-Mechanisms of Disease?
The latest impact factor listed by LetPub is 34.36; CiteScore 45.5, h-index 184.
Which databases index Annual Review of Pathology-Mechanisms of Disease?
According to LetPub and DOAJ records, Annual Review of Pathology-Mechanisms of Disease is indexed in SCIE and Scopus.
Is Annual Review of Pathology-Mechanisms of Disease open access, and what is the APC?
Annual Review of Pathology-Mechanisms of Disease is a subscription journal. Fee information is not available yet; check the journal's website.
Sources and updates
The facts on this page come from LetPub, OpenAlex, Publisher website; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-24). Last updated: .