Journal profile · Genetics & Heredity
AMERICAN JOURNAL OF HUMAN GENETICS
ISSN 0002-9297 · eISSN 1537-6605 · Cell Press · UNITED STATES · Monthly · Founded 1949
AMERICAN JOURNAL OF HUMAN GENETICS: CAS Zone 1 · Biology (2025 upgraded edition, Top journal); impact factor 7.6; hybrid open access; APC about USD 5,150; median 151 days to acceptance (100 articles, last 24 months); community-reported acceptance: hard; 231 articles in 2025; indexed in SCIE and Scopus.
Scope
Aims, scope and focus
AMERICAN JOURNAL OF HUMAN GENETICS is published by Cell Press and is in Zone 1 of Biology in the CAS Journal Ranking (2025 upgraded edition, Top journal). By OpenAlex counts of its recent articles, its largest topics are Genetic Associations and Epidemiology, Genomic variations and chromosomal abnormalities and Genomics and Rare Diseases, together about 28.4% of its articles. Its main subfields are Genetics and Molecular Biology. (generated from OpenAlex topic counts and CAS ranking data)
AJHG provides a record of research and review relating to heredity in humans and to the application of genetic principles in medicine and public policy, as well as in related areas of molecular and cell biology. Topics explored by AJHG include behavioral genetics, biochemical genetics, clinical genetics, cytogenetics, dysmorphology, gene therapy, genetic counseling, genetic epidemiology, genomics, immunogenetics, molecular genetics, neurogenetics, and population genetics.AJHG welcomes submissions of articles and reports on timely subjects concerning all aspects of human genetics, including studies of model organisms that are of direct relevance to human genetics. Manuscripts should be written in a manner accessible to investigators representing diverse backgrounds in human genetics. Descriptions of new statistical methods of general interest to the genetics community are welcome. New methods should be compared to existing methods with the use of real data and/or simulations with parameters (e.g., haplotype frequencies, effect sizes) that are based on a real data example (e.g., marker or haplotype data from the HapMap project). All novel computer programs must be made publicly available by the time that the manuscript is published, and a URL for the website must be included in the Web Resources section of the manuscript. Letters commenting on material previously published in AJHG are also welcome.AJHG does not publish reports of either single mutations or mutational surveys of previously identified loci unless they have unusual significance and substantial insight. Descriptions of new linkage assignments will be considered only if they are of special interest. Reports of negative data will not normally be considered.
From the journal's Aims & Scope
Research area (LetPub): Genetics & Heredity
Main research topics OpenAlex counts of recent articles; shares are approximate
- Genetic Associations and EpidemiologyBiochemistry, Genetics and Molecular Biology12.5%
- Genomic variations and chromosomal abnormalitiesBiochemistry, Genetics and Molecular Biology8.8%
- Genomics and Rare DiseasesBiochemistry, Genetics and Molecular Biology7.2%
- Genetics and Neurodevelopmental DisordersBiochemistry, Genetics and Molecular Biology6.8%
- Genetic Mapping and Diversity in Plants and AnimalsBiochemistry, Genetics and Molecular Biology5.3%
- RNA modifications and cancerBiochemistry, Genetics and Molecular Biology4.8%
- Mitochondrial Function and PathologyBiochemistry, Genetics and Molecular Biology3.8%
- Epigenetics and DNA MethylationBiochemistry, Genetics and Molecular Biology3.7%
Rankings & indexing
CAS ranking and database indexing
CAS Journal Ranking
CAS Journal Ranking, upgraded edition (March 2025)Biology Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 1 |
| Minor | Genetics & Heredity | Zone 1 |
Top journal: yesReview journal: no
CAS Xinrui Journal Ranking (March 2026)Biology Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 1 |
| Minor | Genetics & Heredity | Zone 1 |
Top journal: yesReview journal: not marked
CAS Journal Ranking, previous upgraded edition (December 2023)Biology Zone 1
| Level | Category | Zone |
|---|---|---|
| Major | Biology | Zone 1 |
| Minor | Genetics & Heredity | Zone 1 |
Top journal: yesReview journal: no
Database indexing
SCIEScopusLetPub
International journal early-warning lists: not listed in any editionLetPub
Editions, and major and minor categories, are shown separately and never merged into one zone; check which edition your institution uses before you submit or report.
Metrics
Impact metrics and publication volume
Impact
- Impact factor
- 7.6LetPub ·
- Impact factor (publisher)
- 7.7Publisher website ·
- CiteScore 2026-06
- 12.5LetPub ·
- CiteScore (publisher)
- 12.5Publisher website ·
- SJR 2026-06
- 4.2LetPub ·
- SNIP 2026-06
- 2.47LetPub ·
- h-index
- 280LetPub ·
- h-index
- 392OpenAlex ·
- i10-index
- 6,557OpenAlex ·
- 2-year mean citedness
- 7.23OpenAlex ·
- Self-citation rate
- 5.2%LetPub ·
- Share of gold OA articles
- 33.9%LetPub ·
Volume
- Articles per year
- 191LetPub ·
Articles by year OpenAlex count · 11,269 in total · the current year is incomplete
| Year | Articles | Open access | Citations |
|---|---|---|---|
| 2026 | 156 | 135 | 118 |
| 2025 | 231 | 230 | 1,275 |
| 2024 | 225 | 224 | 3,031 |
| 2023 | 183 | 183 | 5,279 |
| 2022 | 194 | 194 | 8,096 |
| 2021 | 226 | 206 | 11,972 |
Sources count differently and were observed at different times, so each source's own value is kept; "publisher" marks figures from the journal's website.
Review & acceptance
Review time and acceptance
Review time from article dates manuscript dates registered with PubMed · to
151 daysMedian, submission to acceptance · P25–P75 123 days – 229 days
- Acceptance to online
- median 22 days (87 articles)
- Submission to online
- median 182 days
- Sample
- 100 articles with submission and acceptance dates (407 in the window); the latest was accepted on
Only articles that were accepted and published are counted, not the time spent on rejected manuscripts, so this usually runs longer than a publisher's "time to first decision".
Other sources
- Average review time (community reports)
- 3–6 weeksLetPub ·
- Average acceptance (community reports)
- HardLetPub ·
- Submission to first decision
- 3 daysPublisher website ·
- Submission to acceptance
- 148 daysPublisher website ·
Community reports come from authors' own submissions (confidence 0.5) and are not a promise from the journal; for publisher figures, the journal's own definitions apply.
Fees & open access
APC and open-access policy
Hybrid open accessLetPub
A subscription journal in which authors can pay to publish their article open access.
| Source | APC | Fee waiver | License | Observed |
|---|---|---|---|---|
| OpenAlex | USD 5,150 / EUR 4,770 / GBP 4,120 / JPY 638,750 | — | — | |
| Publisher website | USD 5,150 | — | — |
A hybrid journal charges the APC only when the author chooses open access; publishing under the subscription model is usually free.
The journal's website is authoritative for fees; sources were observed at different times and each keeps its own value, without averaging.
Submission
Article types and submission policies (journal website)
Policy excerpts from the journal's websiteOpen access
- Open access Open Access
Article Publishing Charge (APC): USD 5,150 (excluding taxes). The amount you pay may be reduced during submission if applicable.
Source ↗Publisher website ·
Excerpts are quoted from the journal's website; "model summary" lines are written by Workers AI and checked against the text. The journal's website is authoritative.
Profile
Publication details and official links
- Publisher
- Cell Press
- Country or region
- UNITED STATES
- Language
- English
- Frequency
- Monthly
- Founded
- 1949
- ISSN
- 0002-9297
- Electronic ISSN
- 1537-6605
- Official links
- Journal homepage ↗OpenAlex
- Submission system ↗Publisher website
- Special issues ↗Publisher website
FAQ
Frequently asked questions about AMERICAN JOURNAL OF HUMAN GENETICS
What CAS zone is AMERICAN JOURNAL OF HUMAN GENETICS in?
In the 2025 upgraded edition of the CAS Journal Ranking, AMERICAN JOURNAL OF HUMAN GENETICS is in Zone 1 of Biology, and in Zone 1 of the minor category Genetics & Heredity; it is a Top journal. In the 2026 Xinrui edition it is in Zone 1 of Biology. Zones from different editions, and from major and minor categories, are not interchangeable.
What is the impact factor of AMERICAN JOURNAL OF HUMAN GENETICS?
The latest impact factor listed by LetPub is 7.6; CiteScore 12.5, h-index 392.
How long does peer review take at AMERICAN JOURNAL OF HUMAN GENETICS?
Based on the dates recorded on 100 articles published between October 2024 and October 2026 (the last 24 months), the median time from submission to acceptance is 151 days (interquartile range 123–229 days); authors report an average review time of 3–6 weeks; the community-reported acceptance is “Hard”. Article statistics cover accepted papers only, publisher figures follow the journal's own definitions, and community reports come from authors' own submissions; none is a promise from the journal.
Which databases index AMERICAN JOURNAL OF HUMAN GENETICS?
According to LetPub and DOAJ records, AMERICAN JOURNAL OF HUMAN GENETICS is indexed in SCIE and Scopus.
Is AMERICAN JOURNAL OF HUMAN GENETICS open access, and what is the APC?
AMERICAN JOURNAL OF HUMAN GENETICS is a hybrid journal. For open-access publication: APC about USD 5,150.
Sources and updates
The facts on this page come from LetPub, Publisher website, OpenAlex; every figure is tagged with its source and the date it was observed, and conflicting values are kept per source. LetPub source page: view ↗ (archived 2026-08-24). Last updated: .