Drug Design Development and Therapy

期刊简介

研究范围与定位

Drug Design, Development and Therapy is an international, peer-reviewed, open access journal that spans the spectrum of drug design, discovery and development through to clinical applications.The journal is characterized by the rapid reporting of high-quality original research, reviews, expert opinions, commentary and clinical studies in all therapeutic areas. Specific topics covered by the journal include: Drug target identification and validationPhenotypic screening and target deconvolution Biochemical analyses of drug targets and their pathwaysNew methods or relevant applications in molecular/drug design and computer-aided drug discovery*Design, synthesis, and biological evaluation of novel biologically active compounds (including diagnostics or chemical probes)Structural or molecular biological studies elucidating molecular recognition processesFragment-based drug discoveryPharmaceutical/red biotechnologyIsolation, structural characterization, (bio)synthesis, bioengineering and pharmacological evaluation of natural products**Distribution, pharmacokinetics and metabolic transformations of drugs or biologically active compounds in drug developmentDrug delivery and formulation (design and characterization of dosage forms, release mechanisms and in vivo testing)Preclinical development studiesTranslational animal modelsMechanisms of action and signalling pathwaysToxicologyGene therapy, cell therapy and immunotherapyPersonalized medicine and pharmacogenomicsClinical drug evaluationPatient safety and sustained use of medicines.